| 1. |
|
|
| 2. |
- Cheng, Jie, et al.
(författare)
-
Guanidimidazole-quanternized and cross-linked alkaline polymer electrolyte membrane for fuel cell application
- 2016
-
Ingår i: Journal of Membrane Science. - : Elsevier BV. - 0376-7388 .- 1873-3123. ; 501, s. 100-108
-
Tidskriftsartikel (refereegranskat)abstract
- A modified imidazole, namely guanidimidazole (GIm) was designed and synthesized as a novel quaternizing- and cross-linking agent for alkaline polymer electrolyte membrane fabrication. The resulting membrane was more alkali tolerant and swelling resistant than that quaternized purely by 1-methylimidazole owing to the enhanced resonance and cross-linking ability of GIm, the former confirmed by a LUMO (lowest unoccupied molecular orbital) energy calculation. The membrane also showed good ionic conductivity, mechanical strength and thermal stability. A H2/O2 fuel cell using the synthesized membrane showed a peak power density of 39 mW cm−2 at 50 °C. This work preliminarily demonstrates the beneficial effect of imidazole modification by both experimental and computational investigation; it provides a new cation design strategy that may potentially achieve simultaneous improvement of alkali-stability and swelling resistance of alkaline electrolyte membranes.
|
|
| 3. |
- Ericson, Åsa, et al.
(författare)
-
Innovations & Industrial Internet
- 2018
-
Rapport (övrigt vetenskapligt/konstnärligt)abstract
- The Innovations and Industrial Internet project was formed with partners from Luleå University of Technology, Sweden, Centria University of Applied Sciences, Finland, and University of Tromsø, campus Narvik, Norway. The work has addressed an increase in small and medium sized enterprises’ competences of applying modern digital technology to benefit product- and service development in the region. Almost 40 companies have been keenly involved in the project’s activities, which have included, for example, case studies, demonstrations, workshops and seminars. The close academia and company collaborations has resulted in SMEs’ test and evaluation of new technologies, in turn leading to the implementation of new methods that were new to 16 of those companies.The project collaborations have resulted in 9 products and services that were new to the companies. A number of cross-border collaborations among companies and universities across the program region have been finalized, for example a case on 3D printing and boat production which involved all partners competences. The cross-border added value does not only encompass the open accessible milieu bringing all partners expertise together to benefit SMEs in the region, but it also identified and mitigated barriers between knowledge domains, like the ones occurring in value chain collaborations where digital solutions often dissolve some aspects of a problem while simultaneously cause new ones.The project has had a fairly good representation of females in leading positions since the project leader and one country’s leader are females, but also the female representation in activities has been good.The project has been nominated to the Regio Stars Award 2017.
|
|
| 4. |
- Moore, John, et al.
(författare)
-
Developing a Toolbox of supports for small and medium sized manufacturing companies
- 2016
-
Ingår i: 2016 International Symposium on Small-scale Intelligent Manufacturing Systems (SIMS). - New york : IEEE. - 9781509030743 ; , s. 101-104
-
Konferensbidrag (refereegranskat)abstract
- TARGET is a collaborative project involving a partnership of universities and institutes of higher education in UK, Ireland, Norway, Finland and Sweden. The project will develop tools to enhance capacity in regional manufacturing companies to adapt and embrace new technologies and innovation. This is to be done in collaboration with small/medium sized manufacturing engineering companies - developing, applying and piloting the tools through individual companies' processes. The Toolbox developed will consist of subsets such as Digital manufacturing (robotics and simulation), New Ideas and Thinking (human centred and environmental thinking, competitiveness), Business Models and modern Product Innovation. On completion of the Project, the Toolbox of supports will be made available for use through open access to manufacturing companies. The initial project phase with development of a Toolbox suitable for use in all the project partners' regions is presented.
|
|
| 5. |
- Nguyen, Hao G., et al.
(författare)
-
Conditional overexpression of transgenes in megakaryocytes and platelets in vivo
- 2005
-
Ingår i: Blood. - : American Society of Hematology. - 0006-4971 .- 1528-0020. ; 106:5, s. 1559-1564
-
Tidskriftsartikel (refereegranskat)abstract
- Megakaryocyte (MK)-specific transgene expression has proved valuable in studying thrombotic and hemostatic processes. Constitutive expression of genes, however, could result in altered phenotypes due to compensatory mechanisms or lethality. To circumvent these limitations, we used the tetracycline/doxycycline (Tet)-off system to conditionally over-express genes in megakaryocytes and platelets in vivo. We generated 3 transactivator transgenic lines expressing the Tet transactivator element (tTA), under the control of the MK-specific platelet factor 4 promoter (PF4-tTA-VP16). Responder lines were simultaneously generated, each with a bidirectional minimal cytomegalovirus (CMV)-tTA responsive promoter driving prokaryotic β-galactosidase gene, as a cellular reporter, and a gene of interest (in this case, the mitotic regulator Aurora-B). A transactivator founder line that strongly expressed PF4-driven tTA-viral protein 16 (VP16) was crossbred to a responder line. The homozygous double-transgenic mouse line exhibited doxycycline-dependent transgene overexpression in MKs and platelets. Using this line, platelets were conveniently indicated at sites of induced stress by β-galactosidase staining. In addition, we confirmed our earlier report on effects of constitutive expression of Aurora-B, indicating a tight regulation at protein level and a modest effect on MK ploidy. Hence, we generated a new line, PF4-tTA-VP16, that is available for conditionally overexpressing genes of interest in the MK/platelet lineage in vivo.
|
|
