| 1. |
- af Klinteberg, Britt, et al.
(författare)
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Smoking habits – Associations with personality/behavior, platelet monoamine oxidase activity and plasma thyroid hormone levels
- 2017
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Ingår i: Personality and Individual Differences. - : Elsevier. - 0191-8869 .- 1873-3549. ; 118, s. 71-76
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Tidskriftsartikel (refereegranskat)abstract
- The objective was to outline results from our scientific studies on the associations among childhood behavior, adult personality, and biochemical factors in smoking habits. The studies consisted of: (1) follow-up of young criminals and controls, subdivided into risk for antisocial behavior groups, based on childhood rating levels of a projective test; and adult smoking habit groups; and (2) a large group of young adults examined on the same inventories. Personality in terms of KSP and EPQ-I scale scores, controlled for intelligence, indicated that the high and very high risk groups displayed significantly higher self-rated impulsiveness, anxiety, and nonconformity, as compared to the low risk group. Further, the very high risk group subjects, found to be overrepresented among subjects with heavy smoking habits, displayed lower mean platelet MAO-B activity and higher thyroid hormone levels than the low risk group. Thus, the higher the childhood risk for antisocial behavior, the clearer the adult personality pattern making subjects more disposed for smoking appeared; and the higher smoking habits, the stronger the relationships with biochemical measures. Results are discussed in terms of possible underlying mechanisms influencing personality and smoking habits.
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| 2. |
- Ahrén-Moonga, Jennie, et al.
(författare)
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Levels of tumour necrosis factor-alpha and interleukin-6 in severely ill patients with eating disorders
- 2011
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Ingår i: Neuropsychobiology. - : S. Karger AG. - 0302-282X .- 1423-0224. ; 63:1, s. 8-14
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Tidskriftsartikel (refereegranskat)abstract
- Background: The underlying pathophysiology of eating disorders (ED) is dependent on complex interactions between psychological, biological and social factors. The purpose of the present study was to examine a possible increase in cytokines indicating inflammation, as measured by tumour necrosis factor-α (TNF-α) and interleukin-6 (IL-6) in ED patients, and to explore possible relationships between cytokines and self-reported personality traits. Methods: Female patients with severe ED (n = 26) were recruited consecutively from an inpatient clinic and were compared to age-matched healthy females (n = 12). Commercial ELISA tests developed for the measurement of serum levels of TNF-α and IL-6 were employed. Personality traits were measured using Karolinska Scales of Personality. Results: The patient group displayed increased levels of the cytokine TNF-α and a tendency towards increased IL-6 levels. Spearman's rank correlation coefficient was used to examine possible relationships between levels of cytokines and personality traits. The results showed that IL-6 levels were positively related to both somatic and psychic anxiety and to aggression scales, such as irritability and suspicion. Increased levels of TNF-α, in turn, were significantly correlated with high scores on the depression-related anxiety scale Inhibition of Aggression. However, increased levels of cytokines in the ED group did not seem to be mainly associated with symptoms of depression. Conclusion: We cannot rule out the possibility that comorbid conditions in the group contribute to the higher cytokine values. Further studies need to explore the possible influence of cytokines on the severity of ED and whether this might be mediated or moderated by specific personality traits.
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| 3. |
- Lloyd, Christina, et al.
(författare)
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Psychological and existential vulnerability among clinical young women : a quantitative comparison of depression-related subgroups
- 2015
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Ingår i: Mental Health, Religion & Culture. - London : Informa UK Limited. - 1367-4676 .- 1469-9737. ; 18:4, s. 259-272
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Tidskriftsartikel (refereegranskat)abstract
- The objective was to explore psychological and existential vulnerability among clinical young women in Sweden. Females (n = 53) with depression as the most common preliminary diagnosis were investigated through an online questionnaire. Included measures were Karolinska Scales of Personality, Self-concept, Strategies to Handle Negative Emotions, Sense of Coherence, and questions pertaining to existential meaning-making, including religious/spiritual belief. The sample was divided into High (n = 35) and Low/Inter (n = 18) groups according to scores on the anxiety- and depression-related personality scale Inhibition of aggression. Using independent samples t-test, the High group showed signs of significantly higher psychological and existential vulnerability than the Low/Inter group. Salutogenic factors being (1) coming from socially and societally engaged families and (2) being in a functional existential meaning-making process. The conclusion is that vulnerabilities in the psychological and existential domains are linked, especially in individuals high on depression-like aspects of personality. However, no significant differences for religion/spirituality were found. Treatment implications were addressed.
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| 4. |
- Ruchkin, Vladislav V., 1969-, et al.
(författare)
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Dopamine-related receptors, substance dependence, behavioral problems and personality among juvenile delinquents
- 2021
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Ingår i: Personality and Individual Differences. - : Elsevier BV. - 0191-8869 .- 1873-3549. ; 169
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Tidskriftsartikel (refereegranskat)abstract
- The objective was two-fold: to examine possible associations between dopamine-related genetic polymorphisms and (1) substance dependence; and (2) self-reported psychiatric disturbances, behavioral problems, and personality. Genotyping of single nucleotide polymorphisms (SNP: s) in COMT, DAT and DRD4 was conducted in 174 Russian male juvenile inmates (14–18 years of age) subdivided into having a diagnosis of substance dependence or not, as assessed by using K-SADS-PL. The inmates completed several self-reports assessing psychiatric symptoms (CPTS-RI, BDI), behavioral problems (YSR), and personality traits (TCI). Results revealed that juveniles meeting the criteria for substance dependence differed significantly from their counterparts in four polymorphisms, namely COMT rs737865, DAT rs6347, DRD4 C_1611535 and DRD4 exon III; and exact binary regression analysis indicated a highly significant association between the DRD4 C_1611535 GG genotype and substance dependence. One-way ANOVA tests further showed this gene polymorphism variant to be significantly associated with higher levels of posttraumatic stress, thought problems, aggressive behavior, and personality traits indicating antisocial personality disturbances, as compared with the other gene polymorphism variants. In conclusion, the results underscore the role of the DRD4 polymorphism C_1611535 GG genotype for substance dependence, and suggest its associations with different self-reported phenotype characteristics.
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| 5. |
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| 6. |
- af Klinteberg, Britt, et al.
(författare)
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Serotonin, personality and smoking
- 2000
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Ingår i: INTERNATIONAL JOURNAL OF PSYCHOLOGY. - 0020-7594. ; 35:3-4, s. 22-22
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Konferensbidrag (refereegranskat)
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| 7. |
- Beijer, Ulla, et al.
(författare)
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Facets of Male Violence Against Women With Substance Abuse Problems : Women With a Residence and Homeless Women
- 2018
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Ingår i: Journal of Interpersonal Violence. - : SAGE Publications. - 0886-2605 .- 1552-6518. ; 33:9, s. 1391-1411
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Tidskriftsartikel (refereegranskat)abstract
- The aims of this study were to investigate the type and extent to which women with substance abuse problems have been exposed to male violence during their lifetime, and to examine possible differences between women with a residence (WR) and homeless women (HW). The total sample included 79 women (WR, n = 35; HW, n = 44; M age = 47.8 years). Of the total sample, 72 women (91%) had experienced different kinds of male violence, 88% from former partners, and 26% from male friends or acquaintances. Of the 72 women, 71% further reported “Countless occasions of violent events,” and 36% had been forced to commit criminal acts. Abused women who had been forced to commit criminal acts were significantly more frequently found to be homeless, have reported parental alcohol and/or drug problems, have witnessed domestic violence in childhood, have been victims of sexual violence, have used illicit drugs as a dominant preparation, and have injected illicit drugs. Almost half of the abused women (46%) met criteria for posttraumatic stress disorder (PTSD), where HW showed an almost 4-time higher risk (RR 3.78) than WR. In conclusion there is a particular vulnerability in women with substance abuse to male violence, which has an important impact on their health status. Thus, from a public health perspective, it is suggested that for those women who have experienced male violence, treatment protocols need to include both assessing and addressing the impact of such experience in relation to substance abuse as well as concomitant health concerns.
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| 8. |
- Birath, Christina Scheffel, et al.
(författare)
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Women with Substance Abuse Problems Exposed to Men's Violence - A Public Mental Health Challenge
- 2013
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Ingår i: Journal of Addiction Research & Therapy. - : OMICS Publishing Group. - 2155-6105. ; 4:2, s. 1-7
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Tidskriftsartikel (refereegranskat)abstract
- Objective: To explore self-rated physical and psychological health in two groups of women with substance misuse problems, subjected to male violence.Methods: An examination of the health situation for women with substance dependence being exposed to male violence during life. The study took place in a Swedish context exploring data from 35 women with housing (WwH) and 44 homeless women (HW), regarding posttraumatic stress disorder symptoms, psychological and physical problems. Mann-Whitney U-test and Pearson’s correlation coefficient were used to calculate differences between groups and correlations.Results: The proportion of women being exposed to male violence during life for the studied group was 91% (72 of 79 women; WwH 29; HW 43). It was found that the WwH had physical health problems but compared to the HW, significantly less frequent. Regarding psychological health problems, both groups were suffering from self-reported problems, most notably in variables measuring stress susceptibility and embitterment, where both WwH and HW had scores markedly above norm mean scores. The HW had overall a poorer mental health profile as compared to the WwH. The WwH still maintained a foundation in the society compared to the HW regarding housing (100/0%), and custody over their children (91/0%).Conclusion: The study indicated that women with substance dependence and those who are victims of male violence have major problems with both their psychological and physical health. Particularly vulnerable are the HW. Past experiences of violence that have not been processed can further aggravate the women’s health. Thus, we suggest initiating the process of asking women if they have experienced violence in order to then be able to provide appropriate treatment interventions. For the WwH, this process may lead to a prevention of serious consequences for both their housing situation and for their health.
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| 9. |
- Isaksson, Johan, et al.
(författare)
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Exploring possible association between D beta H genotype (C1021T), early onset of conduct disorder and psychopathic traits in juvenile delinquents
- 2016
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Ingår i: European Archives of Psychiatry and Clinical Neuroscience. - : Springer Science and Business Media LLC. - 0940-1334 .- 1433-8491. ; 266:8, s. 771-773
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Tidskriftsartikel (refereegranskat)abstract
- Early onset of conduct disorder (CD) with callous-unemotional traits has been linked to low levels of dopamine β-hydroxylase (DβH), an enzyme involved in dopamine turnover. The C1021T polymorphism in the DβH gene is a major quantitative-trait locus, regulating the level of DβH. In this study of juvenile delinquents from Northern Russia (n = 180), the polymorphism at -1021 was associated neither with early-onset CD nor with psychopathic traits. Association was found between psychopathic traits and early-onset CD, ADHD and mania.
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| 10. |
- Isaksson, Johan, et al.
(författare)
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Exploring possible association between DβH genotype (C1021T), early onset of conduct disorder and psychopathic traits in juvenile delinquents.
- 2016
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Ingår i: European Archives of Psychiatry and Clinical Neuroscience. - : Springer Science and Business Media LLC. - 0940-1334 .- 1433-8491. ; 266:8, s. 771-773
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Tidskriftsartikel (refereegranskat)abstract
- Early onset of conduct disorder (CD) with callous-unemotional traits has been linked to low levels of dopamine β-hydroxylase (DβH), an enzyme involved in dopamine turnover. The C1021T polymorphism in the DβH gene is a major quantitative-trait locus, regulating the level of DβH. In this study of juvenile delinquents from Northern Russia (n = 180), the polymorphism at -1021 was associated neither with early-onset CD nor with psychopathic traits. Association was found between psychopathic traits and early-onset CD, ADHD and mania.
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