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Träfflista för sökning "WFRF:(Auricchio Angelo) srt2:(2007-2009)"

Sökning: WFRF:(Auricchio Angelo) > (2007-2009)

  • Resultat 1-5 av 5
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1.
  • Kirchhof, Paulus, et al. (författare)
  • Outcome parameters for trials in atrial fibrillation: executive summary
  • 2007
  • Ingår i: European Heart Journal. - : Oxford University Press. - 1522-9645. ; 28:22, s. 2803-2817
  • Forskningsöversikt (refereegranskat)abstract
    • Atrial fibrillation (AF), the most common atrial arrhythmia, has a complex aetiology and causes relevant morbidity and mortality due to different mechanisms, including but not limited to stroke, heart failure, and tachy- or bradyarrhythmia. Current therapeutic options (rate control, rhythm control, antithrombotic therapy, 'upstream therapy') only prevent a part of this burden of disease. Several new treatment modalities are therefore under evaluation in controlled trials. Given the multifold clinical consequences of AF, trials in AF patients should assess the effect of therapy in each of the main outcome domains. This paper describes an expert consensus of required outcome parameters in seven relevant outcome domains, namely death, stroke, symptoms and quality of life, rhythm, left ventricular function, cost, and emerging outcome parameters. In addition to these 'requirements' for outcome assessment in AF trials, further, more detailed outcome parameters are described. In addition to a careful selection of a relevant primary outcome parameter, coverage of outcomes in all major domains of AF- related morbidity and mortality is desirable for any clinical trial in AF.
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2.
  • Kirchhof, Paulus, et al. (författare)
  • Outcome parameters for trials in atrial fibrillation - Recommendations from a consensus conference organized by the German atrial fibrillation competence NETwork and the European Heart Rhythm Association
  • 2007
  • Ingår i: Europace. - : Oxford University Press. - 1532-2092. ; 9:11, s. 1006-1023
  • Forskningsöversikt (refereegranskat)abstract
    • Atrial fibrillation (AF), the most common atria[ arrhythmia, has a complex aetiology and causes relevant morbidity and mortality due to different mechanisms, including but not limited to stroke, heart failure, and tachy- or bradyarrhythmia. Current therapeutic options (rate control, rhythm control, antithrombotic therapy, 'upstream therapy') only prevent a part of this burden of disease. New treatment modalities are therefore currently under evaluation in clinical trials. Given the multifold clinical consequences of AF, controlled trials in AF patients should assess the effect of therapy in each of the main outcome domains. This paper describes an expert consensus of required outcome parameters in seven relevant outcome domains, namely death, stroke, symptoms and quality of life, rhythm, left ventricular function, cost, and emerging outcome parameters. In addition to these 'requirements' for outcome assessment in AF trials, further outcome parameters are described in each outcome domain. In addition to a careful selection of a relevant primary outcome parameter, coverage of outcomes in all major domains of AF-related morbidity and mortality is desirable for any clinical trial in AF.
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5.
  • Vardas, Panos E., et al. (författare)
  • Orientações para pacing cardíaco e terapia deressincronização cardíaca
  • 2008
  • Ingår i: Revista portuguesa de cardiologia : orgão oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology. - 0870-2551. ; 27:5, s. 639-687
  • Tidskriftsartikel (refereegranskat)
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  • Resultat 1-5 av 5

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