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Träfflista för sökning "WFRF:(Jaffe A. S.) srt2:(2010-2014)"

Sökning: WFRF:(Jaffe A. S.) > (2010-2014)

  • Resultat 1-10 av 16
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1.
  • Abazov, V. M., et al. (författare)
  • Search for neutral Higgs bosons in the multi-b-jet topology in 5.2 fb(-1) of p(p)over-bar collisions at root s=1.96 TeV
  • 2011
  • Ingår i: Physics Letters B. - : Elsevier BV. - 0370-2693 .- 1873-2445. ; 698:2, s. 97-104
  • Tidskriftsartikel (refereegranskat)abstract
    • Data recorded by the DO experiment at the Fermilab Tevatron Collider are analyzed to search for neutral Higgs bosons produced in association with b quarks. The search is performed in the three-b-quark channel using multijet-triggered events corresponding to an integrated luminosity of 5.2 fb(-1). In the absence of any significant excess above background, limits are set on the cross section multiplied by the branching ratio in the Higgs boson mass range 90 to 300 GeV, extending the excluded regions in the parameter space of the minimal supersymmetric standard model. (C) 2011 Elsevier B.V. All rights reserved.
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2.
  • Abazov, V. M., et al. (författare)
  • Search for W' -> tb resonances with left- and right-handed couplings to fermions D0 Collaboration
  • 2011
  • Ingår i: Physics Letters B. - : Elsevier BV. - 0370-2693 .- 1873-2445. ; 699:3, s. 145-150
  • Tidskriftsartikel (refereegranskat)abstract
    • We present a search for the production of a heavy gauge boson, W', that decays to third-generation quarks, by DO Collaboration in p (p) over bar) collisions at root s = 1.96 TeV. We set 95% confidence level upper limits on the production cross section times branching fraction. For the first time, we set limits for arbitrary combinations of left-and right-handed couplings of the W' boson to fermions. For couplings with the same strength as for the standard model W boson, we set the following limits, assuming that there are right-handed neutrinos nu(R) for all three generations with M(W') > m(nu(R)): M(W') > 863 GeV for purely left-handed couplings, M(W') > 885 GeV for purely right-handed couplings, and M(W') > 916 GeV if both left-and right-handed couplings are present. The limit for right-handed couplings improves for M(W') < m(nu(R)) to M(W') > 890 GeV.
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3.
  • Abazov, V. M., et al. (författare)
  • Combination of searches for anomalous top quark couplings with 5.4 fb(-1) of p(p)over-bar collisions
  • 2012
  • Ingår i: Physics Letters B. - : Elsevier BV. - 0370-2693 .- 1873-2445. ; 713:3, s. 165-171
  • Tidskriftsartikel (refereegranskat)abstract
    • We present measurements of the tWb coupling form factors using information from electroweak single top quark production and from the helicity of W bosons from top quark decays in t (t) over bar events. We set upper limits on anomalous tWb coupling form factors using data collected with the DO detector at the Tevatron p (p) over bar collider corresponding to an integrated luminosity of 5.4 fb(-1).
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4.
  • Bradnam, K. R., et al. (författare)
  • Assemblathon 2 : Evaluating de novo methods of genome assembly in three vertebrate species
  • 2013
  • Ingår i: GigaScience. - : BioMed Central (BMC). - 2047-217X. ; 2:1
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: The process of generating raw genome sequence data continues to become cheaper, faster, and more accurate. However, assembly of such data into high-quality, finished genome sequences remains challenging. Many genome assembly tools are available, but they differ greatly in terms of their performance (speed, scalability, hardware requirements, acceptance of newer read technologies) and in their final output (composition of assembled sequence). More importantly, it remains largely unclear how to best assess the quality of assembled genome sequences. The Assemblathon competitions are intended to assess current state-of-the-art methods in genome assembly. Results: In Assemblathon 2, we provided a variety of sequence data to be assembled for three vertebrate species (a bird, a fish, and snake). This resulted in a total of 43 submitted assemblies from 21 participating teams. We evaluated these assemblies using a combination of optical map data, Fosmid sequences, and several statistical methods. From over 100 different metrics, we chose ten key measures by which to assess the overall quality of the assemblies. Conclusions: Many current genome assemblers produced useful assemblies, containing a significant representation of their genes and overall genome structure. However, the high degree of variability between the entries suggests that there is still much room for improvement in the field of genome assembly and that approaches which work well in assembling the genome of one species may not necessarily work well for another.
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6.
  • Thygesen, Kristian, et al. (författare)
  • Third universal definition of myocardial infarction
  • 2012
  • Ingår i: Journal of the American College of Cardiology. - : Elsevier BV. - 0735-1097 .- 1558-3597. ; 60:16, s. 1581-1598
  • Tidskriftsartikel (refereegranskat)
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7.
  • Saenger, A. K., et al. (författare)
  • Multicenter analytical evaluation of a high-sensitivity troponin T assay
  • 2011
  • Ingår i: Clinica Chimica Acta. - : Elsevier BV. - 0009-8981 .- 1873-3492. ; 412:9-10, s. 748-754
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: High-sensitivity cardiac troponin assays are being introduced clinically for earlier diagnosis of acute myocardial infarction (AMI). We evaluated the analytical performance of a high-sensitivity cardiac troponin T assay (hscTnT. Roche Diagnostics) in a multicenter, international trial. Methods: Three US and 5 European sites evaluated hscTnT on the Modular (R) Analytics E170, cobas (R) 6000, Elecsys 2010, and cobas (R) e 411. Precision, accuracy, reportable range, an inter-laboratory comparison trial, and the 99th percentile of a reference population were assessed. Results: Total imprecision (CVs) were 4.6-36.8% between 3.4 and 10.3 ng/L hscTnT. Assay linearity was up to 10,000 ng/L and the limit of blank and detection were 3 and 5 ng/L, respectively. The 99th percentile reference limit was 14.2 ng/L (n = 533). No significant differences between specimen types, assay incubation time, or reagent lots existed. A substantial positive bias (76%) exists between the 4th generation and hscTnT assays at the low end of the measuring range (< 50 ng/L). hscTnT serum pool concentrations were within 2SD limits of the mean of means in the comparison trial, indicating comparable results across multiple platforms and laboratories. Conclusion: The Roche hscTnT assay conforms to guideline precision requirements and will likely identify additional patients with myocardial injury suspicious for AMI.
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9.
  • Brawand, David, et al. (författare)
  • The genomic substrate for adaptive radiation in African cichlid fish
  • 2014
  • Ingår i: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 513:7518, s. 375-381
  • Tidskriftsartikel (refereegranskat)abstract
    • Cichlid fishes are famous for large, diverse and replicated adaptive radiations in the Great Lakes of East Africa. To understand themolecular mechanisms underlying cichlid phenotypic diversity, we sequenced the genomes and transcriptomes of five lineages of African cichlids: the Nile tilapia (Oreochromis niloticus), an ancestral lineage with low diversity; and four members of the East African lineage: Neolamprologus brichardi/pulcher (older radiation, Lake Tanganyika), Metriaclima zebra (recent radiation, Lake Malawi), Pundamilia nyererei (very recent radiation, Lake Victoria), and Astatotilapia burtoni (riverine species around Lake Tanganyika). We found an excess of gene duplications in the East African lineage compared to tilapia and other teleosts, an abundance of non-coding element divergence, accelerated coding sequence evolution, expression divergence associated with transposable element insertions, and regulation by novel microRNAs. In addition, we analysed sequence data from sixty individuals representing six closely related species from Lake Victoria, and show genome-wide diversifying selection on coding and regulatory variants, some of which were recruited from ancient polymorphisms. We conclude that a number of molecular mechanisms shaped East African cichlid genomes, and that amassing of standing variation during periods of relaxed purifying selection may have been important in facilitating subsequent evolutionary diversification.
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10.
  • Alfoeldi, Jessica, et al. (författare)
  • The genome of the green anole lizard and a comparative analysis with birds and mammals
  • 2011
  • Ingår i: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 477:7366, s. 587-591
  • Tidskriftsartikel (refereegranskat)abstract
    • The evolution of the amniotic egg was one of the great evolutionary innovations in the history of life, freeing vertebrates from an obligatory connection to water and thus permitting the conquest of terrestrial environments(1). Among amniotes, genome sequences are available for mammals and birds(2-4), but not for non-avian reptiles. Here we report the genome sequence of the North American green anole lizard, Anolis carolinensis. We find that A. carolinensis microchromosomes are highly syntenic with chicken microchromosomes, yet do not exhibit the high GC and low repeat content that are characteristic of avian microchromosomes(2). Also, A. carolinensis mobile elements are very young and diverse-more so than in any other sequenced amniote genome. The GC content of this lizard genome is also unusual in its homogeneity, unlike the regionally variable GC content found in mammals and birds(5). We describe and assign sequence to the previously unknown A. carolinensis X chromosome. Comparative gene analysis shows that amniote egg proteins have evolved significantly more rapidly than other proteins. An anole phylogeny resolves basal branches to illuminate the history of their repeated adaptive radiations.
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  • Resultat 1-10 av 16
  • [1]2Nästa

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