SwePub
Sök i SwePub databas

  Utökad sökning

Träfflista för sökning "WFRF:(Kaiser M) srt2:(2005-2009)"

Sökning: WFRF:(Kaiser M) > (2005-2009)

  • Resultat 1-10 av 33
  • [1]234Nästa
Sortera/gruppera träfflistan
   
NumreringReferensOmslagsbildHitta
1.
  • Aad, G., et al. (författare)
  • The ATLAS Experiment at the CERN Large Hadron Collider
  • 2008
  • Ingår i: Journal of Instrumentation. - : IOP Publishing. - 1748-0221. ; 3:S08003:3, s. S08003-
  • Forskningsöversikt (refereegranskat)abstract
    • The ATLAS detector as installed in its experimental cavern at point 1 at CERN is described in this paper. A brief overview of the expected performance of the detector when the Large Hadron Collider begins operation is also presented.
  •  
2.
  • Mattsson, Niklas, 1979, et al. (författare)
  • CSF biomarkers and incipient Alzheimer disease in patients with mild cognitive impairment.
  • 2009
  • Ingår i: JAMA : the journal of the American Medical Association. - : American Medical Association. - 1538-3598 .- 0098-7484. ; 302:4, s. 385-93
  • Tidskriftsartikel (refereegranskat)abstract
    • CONTEXT: Small single-center studies have shown that cerebrospinal fluid (CSF) biomarkers may be useful to identify incipient Alzheimer disease (AD) in patients with mild cognitive impairment (MCI), but large-scale multicenter studies have not been conducted. OBJECTIVE: To determine the diagnostic accuracy of CSF beta-amyloid(1-42) (Abeta42), total tau protein (T-tau), and tau phosphorylated at position threonine 181 (P-tau) for predicting incipient AD in patients with MCI. DESIGN, SETTING, AND PARTICIPANTS: The study had 2 parts: a cross-sectional study involving patients with AD and controls to identify cut points, followed by a prospective cohort study involving patients with MCI, conducted 1990-2007. A total of 750 individuals with MCI, 529 with AD, and 304 controls were recruited by 12 centers in Europe and the United States. Individuals with MCI were followed up for at least 2 years or until symptoms had progressed to clinical dementia. MAIN OUTCOME MEASURES: Sensitivity, specificity, positive and negative likelihood ratios (LRs) of CSF Abeta42, T-tau, and P-tau for identifying incipient AD. RESULTS: During follow-up, 271 participants with MCI were diagnosed with AD and 59 with other dementias. The Abeta42 assay in particular had considerable intersite variability. Patients who developed AD had lower median Abeta42 (356; range, 96-1075 ng/L) and higher P-tau (81; range, 15-183 ng/L) and T-tau (582; range, 83-2174 ng/L) levels than MCI patients who did not develop AD during follow-up (579; range, 121-1420 ng/L for Abeta42; 53; range, 15-163 ng/L for P-tau; and 294; range, 31-2483 ng/L for T-tau, P < .001). The area under the receiver operating characteristic curve was 0.78 (95% confidence interval [CI], 0.75-0.82) for Abeta42, 0.76 (95% CI, 0.72-0.80) for P-tau, and 0.79 (95% CI, 0.76-0.83) for T-tau. Cut-offs with sensitivity set to 85% were defined in the AD and control groups and tested in the MCI group, where the combination of Abeta42/P-tau ratio and T-tau identified incipient AD with a sensitivity of 83% (95% CI, 78%-88%), specificity 72% (95% CI, 68%-76%), positive LR, 3.0 (95% CI, 2.5-3.4), and negative LR, 0.24 (95% CI, 0.21-0.28). The positive predictive value was 62% and the negative predictive value was 88%. CONCLUSIONS: This multicenter study found that CSF Abeta42, T-tau, and P-tau identify incipient AD with good accuracy, but less accurately than reported from single-center studies. Intersite assay variability highlights a need for standardization of analytical techniques and clinical procedures.
  •  
3.
  • Monks, P. S., et al. (författare)
  • Atmospheric composition change : global and regional air quality
  • 2009
  • Ingår i: Atmospheric Environment. - 1352-2310 .- 1873-2844. ; 43:33, s. 5268-5350
  • Forskningsöversikt (refereegranskat)abstract
    • Air quality transcends all scales with in the atmosphere from the local to the global with handovers and feedbacks at each scale interaction. Air quality has manifold effects on health, ecosystems heritage and, climate. In this review the state of scientific understanding in relation to global and regional air quality is outlined. The review discusses air quality, in terms of emissions, processing and transport of trace gases and aerosols. New insights into the characterization of both natural and anthropogenic emissions are reviewed looking at both natural (e.g. dust and lightning) as well as plant emissions. Trends in anthropogenic emissions both by region and globally are discussed as well as biomass burning emissions. In terms of chemical processing the major air quality elements of ozone, non-methane hydrocarbons, nitrogen oxides and aerosols are covered. A number of topics are presented as a way of integrating the process view into the atmospheric context; these include the atmospheric oxidation efficiency, halogen and HOx chemistry, nighttime chemistry, tropical chemistry, heat waves, megacities, biomass burning and the regional hot spot of the Mediterranean. New findings with respect to the transport of pollutants across the scales are discussed, in particular the move to quantify the impact of long-range transport on regional air quality. Gaps and research questions that remain intractable are identified. The review concludes with a focus of research and policy questions for the coming decade. In particular, the policy challenges for concerted air quality and climate change policy (co-benefit) are discussed.
  •  
4.
  • Monks, P.S., et al. (författare)
  • Atmospheric Composition Change - Global and Regional Air Quality
  • 2009
  • Ingår i: Atmospheric Environment. - 1352-2310. ; 43:33, s. 5268-5350
  • Tidskriftsartikel (refereegranskat)abstract
    • Air quality transcends all scales with the atmosphere from the local to the global with handovers and feedbacks at each scale interaction. Air quality has manifold effects on health, ecosystems, heritage and climate. In this review the state of scientific understanding in relation to global and regional air quality is outlined. The review discusses air quality, in terms of emissions, processing and transport of trace gases and aerosols. New insights into the characterization of both natural and anthropogenic emissions are reviewed looking at both natural (e.g. dust and lightning) as well as plant emissions. Trends in anthropogenic emissions both by region and globally are discussed as well as biomass burning emissions. In terms of chemical processing the major air quality elements of ozone, non-methane hydrocarbons, nitrogen oxides and aerosols are covered. A number of topics are presented as a way of integrating the process view into the atmospheric context; these include the atmospheric oxidation efficiency, halogen and HOx chemistry, night-time chemistry, tropical chemistry, heat waves, megacities, biomass burning and the regional hot spot of the Mediterranean. New findings in respect of the transport of pollutants across the scales are discussed, in particular the move to quantify the impact of long-range transport on regional air quality. Gaps and research questions that remain intractable are identified, the review concludes with a focus of research and policy questions for the coming decade. In particular, the policy challenges for concerted air quality and climate change policy (co-benefit) are discussed.
  •  
5.
  • Falconer, D., et al. (författare)
  • New Air-interface Technologies and Deployment Concepts
  • 2006
  • Ingår i: Technologies for the Wireless Future: Wireless World Research Forum (WWRF). - : John Wiley & Sons. - 0470029056 - 9780470029053 ; , s. 131-226
  • Bokkapitel (övrigt vetenskapligt)
  •  
6.
  •  
7.
  • Roila, F., et al. (författare)
  • Prevention of chemotherapy- and radiotherapy-induced emesis : Results of the 2004 Perugia International Antiemetic Consensus Conference
  • 2006
  • Ingår i: Annals of Oncology. - 0923-7534 .- 1569-8041. ; 17:1, s. 20-28
  • Forskningsöversikt (refereegranskat)abstract
    • Background: In the late 1990s, several professional organizations convened antiemetic guideline groups and published the findings of these expert panels. Each of these documents was based on analyses of the available published trials and provided nearly similar recommendations. Nonetheless, small differences in emetic risk categories and treatment recommendations led to confusion in antiemetics selection. With the emergence of new findings and agents since the guidelines were initially published, many of the oncology professional societies have updated the antiemetic guidelines. Materials and methods: A literature review up to March 2004 was carried out using MEDLINE with evaluation of the evidence by an expert panel composed of 23 oncology professionals in clinical medicine, medical oncology, radiation oncology, oncology nursing, statistics, pharmacy, medical policy and decision making, and pharmacology. The experts represented nine oncology professional societies and came from 11 different countries on four continents. Results: Recommendations on antiemetic regimens to prevent emesis induced by high, moderate, low and minimal risk chemotherapy were suggested as well as management of anticipatory emesis. Furthermore, recommendations for refractory emesis, emesis induced by high-dose chemotherapy and radiotherapy and for antiemetics in children receiving chemotherapy were elaborated. Conclusions: Recommendations about antiemetic prophylaxis in patients receiving treatment with chemo- and radiotherapy have been updated by representatives of nine oncological organizations. © 2005 European Society for Medical Oncology.
  •  
8.
  •  
9.
  • Farrell, W. M., et al. (författare)
  • Mass unloading along the inner edge of the Enceladus plasma torus
  • 2008
  • Ingår i: Geophysical Research Letters. - 0094-8276 .- 1944-8007. ; 35:2, s. L02203-
  • Tidskriftsartikel (refereegranskat)abstract
    • A major discovery made by the Cassini spacecraft at Saturn was the substantial mass ejection from the south pole of Enceladus. Previous studies show that this ejected gas can become ionized and subsequently load mass onto the connecting magnetic field lines near the moon. Radial diffusion then allows the mass-loaded field lines to move outward to similar to 15 R-s and inward to similar to 2 R-s, forming a plasma torus. We demonstrate herein that the mass is also '' unloaded '' along the inner edge of this plasma torus the edge incident with the plasma-absorbing A-ring. Interpreting down-drifting z-mode tones from active sites along the inner edge of the ion torus as emission near the local electron plasma frequency, f(pe), we can remotely-monitor this reduction in plasma density along the torus inner edge as a function time. We find that the down-drift of the z-mode tones corresponds typically to a plasma density change dn/dt similar to - 5x10(-4)/cm(3)-s and when integrated over an annulus defined by the outer edge of the A-ring, corresponds to a mass loss of similar to 40 kg/s. Using the z-mode tones, we also find locations where plasma mass from the ring-ionosphere is possibly loaded at 1 - 2 kg/s onto field lines near the Cassini gap.
  •  
10.
  • Kaiser, M. J., et al. (författare)
  • Validation of the Mini Nutritional Assessment short-form (MNAA (R)-SF) : A practical tool for identification of nutritional status
  • 2009
  • Ingår i: The Journal of Nutrition, Health & Aging. - 1279-7707 .- 1760-4788. ; 13:9, s. 782-788
  • Tidskriftsartikel (refereegranskat)abstract
    • To validate a revision of the Mini Nutritional Assessment short-form (MNAA (R)-SF) against the full MNA, a standard tool for nutritional evaluation. A literature search identified studies that used the MNA for nutritional screening in geriatric patients. The contacted authors submitted original datasets that were merged into a single database. Various combinations of the questions on the current MNA-SF were tested using this database through combination analysis and ROC based derivation of classification thresholds. Twenty-seven datasets (n=6257 participants) were initially processed from which twelve were used in the current analysis on a sample of 2032 study participants (mean age 82.3y) with complete information on all MNA items. The original MNA-SF was a combination of six questions from the full MNA. A revised MNA-SF included calf circumference (CC) substituted for BMI performed equally well. A revised three-category scoring classification for this revised MNA-SF, using BMI and/or CC, had good sensitivity compared to the full MNA. The newly revised MNA-SF is a valid nutritional screening tool applicable to geriatric health care professionals with the option of using CC when BMI cannot be calculated. This revised MNA-SF increases the applicability of this rapid screening tool in clinical practice through the inclusion of a "malnourished" category.
  •  
Skapa referenser, mejla, bekava och länka
  • Resultat 1-10 av 33
  • [1]234Nästa
Typ av publikation
tidskriftsartikel (24)
konferensbidrag (4)
forskningsöversikt (3)
rapport (1)
bokkapitel (1)
Typ av innehåll
refereegranskat (29)
övrigt vetenskapligt (4)
Författare/redaktör
Kaiser, R (8)
Sonnerborg, A (6)
Altmann, A (6)
Schulter, E (6)
Zazzi, M (6)
Lengauer, T (6)
visa fler...
Peres, Y (5)
Incardona, F (4)
Rhee, SY (3)
Shafer, RW (3)
Fessel, WJ (3)
Rosen-Zvi, M (3)
Boyd, J. (2)
Kaiser, S. (2)
Zhao, X. (2)
Kulmala, M (2)
Prevot, A. S. H. (2)
von Glasow, R. (2)
Struck, D (2)
Vautard, R. (2)
Hjorth, J. (2)
Guenther, A. (2)
Cederholm, T (2)
Gronlund, H (2)
Vellas, B (2)
Baltensperger, U. (2)
van der Flier, Wiesj ... (2)
Sing, T (2)
Vermeiren, H (2)
Winters, B (2)
Van Craenenbroeck, E (2)
Van der Borght, K (2)
Bacheler, L (2)
Van Vlijmen, H (2)
Prosperi, M (2)
Aharoni, E (2)
Neuvirth, H (2)
Buch, J (2)
Gafvelin, G (2)
Gurnett, D. A. (2)
Wahlund, Jan-Erik (2)
Palmer, P. I. (2)
Laj, P. (2)
Sellegri, K. (2)
Uter, W. (2)
Farrell, W. M. (2)
Kaiser, A. (2)
McFiggans, G. (2)
Maggio, M (2)
Metzger, A. (2)
visa färre...
Lärosäte
Karolinska Institutet (12)
Uppsala universitet (7)
Lunds universitet (4)
Kungliga Tekniska Högskolan (3)
Umeå universitet (2)
Stockholms universitet (2)
visa fler...
Linköpings universitet (2)
Chalmers tekniska högskola (2)
Göteborgs universitet (1)
Jönköping University (1)
Södertörns högskola (1)
visa färre...
Språk
Engelska (32)
Odefinierat språk (1)
Forskningsämne (UKÄ/SCB)
Naturvetenskap (9)
Medicin och hälsovetenskap (2)
Teknik (1)
Samhällsvetenskap (1)

År

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy