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Sökning: WFRF:(Metspalu Mait) > (2010-2014) > (2010)

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1.
  • Behar, Doron M., et al. (författare)
  • The genome-wide structure of the Jewish people
  • 2010
  • Ingår i: Nature. - : Macmilan. - 0028-0836 .- 1476-4687. ; 466:7303, s. 238-242
  • Tidskriftsartikel (refereegranskat)abstract
    • A comparison of genomic data from 14 Jewish communities across the world with data from 69 non-Jewish populations reveals a close relationship between most of today's Jews and non-Jewish populations from the Levant. This fits in with the idea that most contemporary Jews are descended from ancient Hebrew and Israelite residents of the Levant. By contrast, the Ethiopian and Indian Jewish communities cluster with neighbouring non-Jewish populations in Ethiopia and western India, respectively. This may be partly because a greater degree of genetic, religious and cultural crossover took place when the Jewish communities in these areas became established.
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2.
  • Rasmussen, Morten, et al. (författare)
  • Ancient human genome sequence of an extinct Palaeo-Eskimo
  • 2010
  • Ingår i: Nature. - 0028-0836 .- 1476-4687. ; 463:7282, s. 757-762
  • Tidskriftsartikel (refereegranskat)abstract
    • We report here the genome sequence of an ancient human. Obtained from ∼4,000-year-old permafrost-preserved hair, the genome represents a male individual from the first known culture to settle in Greenland. Sequenced to an average depth of 20×, we recover 79% of the diploid genome, an amount close to the practical limit of current sequencing technologies. We identify 353,151 high-confidence single-nucleotide polymorphisms (SNPs), of which 6.8% have not been reported previously. We estimate raw read contamination to be no higher than 0.8%. We use functional SNP assessment to assign possible phenotypic characteristics of the individual that belonged to a culture whose location has yielded only trace human remains. We compare the high-confidence SNPs to those of contemporary populations to find the populations most closely related to the individual. This provides evidence for a migration from Siberia into the New World some 5,500 years ago, independent of that giving rise to the modern Native Americans and Inuit.
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