| 1. |
- Brohede, J, et al.
(författare)
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Microsatellite evolution: polarity of substitutions within repeats and neutrality of flanking sequences
- 1999
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Ingår i: PROCEEDINGS OF THE ROYAL SOCIETY OF LONDON SERIES B-BIOLOGICAL SCIENCES. - : ROYAL SOC LONDON. - 0962-8452. ; 266:1421, s. 825-833
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- Though extensively used in a variety of disciplines, the evolutionary pattern of microsatellite sequences is still unclear. We addressed several questions relating to microsatellite evolution by analysing historically accumulated mutation events in a larg
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| 2. |
- Ellegren, H, et al.
(författare)
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Flow cytometry for sexing birds - Reply
- 1997
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Ingår i: TRENDS IN ECOLOGY & EVOLUTION. - : ELSEVIER SCI LTD. ; 12:12
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Annan publikation (övrigt vetenskapligt/konstnärligt)
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| 3. |
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| 4. |
- Ellegren, H
(författare)
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Inbreeding and relatedness in Scandinavian grey wolves Canis lupus
- 1999
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Ingår i: HEREDITAS. - : HEREDITAS-DISTRIBUTION. - 0018-0661. ; 130:3, s. 239-244
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- Management of small and threatened populations may require detailed knowledge about the genetic status of individuals and the genetic relatedness between individuals. I show here that individual heterozygosity at a set of 29 microsatellite loci correlates
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| 5. |
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| 6. |
- Ellegren, H, et al.
(författare)
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New tools for sex identification and the study of sex allocation in birds
- 1997
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Ingår i: TRENDS IN ECOLOGY & EVOLUTION. - : ELSEVIER SCI LTD. ; 12:7, s. 255-259
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Recension (övrigt vetenskapligt/konstnärligt)abstract
- The recent development of simple, DNA-based methods for the determination of an individual's sex will make possible large-scale studies of sex allocation and the consequence of gender in birds. Birds provide ideal systems for studying these questions in v
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| 7. |
- Ellegren, H, et al.
(författare)
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Sex ratio adjustment in relation to paternal attractiveness in a wild bird population
- 1996
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Ingår i: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. - : NATL ACAD SCIENCES. - 0027-8424. ; 93:21, s. 11723-11728
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- When the relative fitness of sons and daughters differs, sex-allocation theory predicts that it would be adaptive for individuals to adjust their investment in different sexes of offspring. Sex ratio adjustment by females in response to the sexual attract
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| 8. |
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| 9. |
- Ellegren, H, et al.
(författare)
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The genetical history of an isolated population of the endangered grey wolf Canis lupus : A study of nuclear and mitochondrial polymorphisms
- 1996
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Ingår i: Philosophical Transactions of the Royal Society of London. Biological Sciences. - : The Royal Society. - 0962-8436 .- 1471-2970. ; 351:1348, s. 1661-1669
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Tidskriftsartikel (refereegranskat)abstract
- The grey wolf was thought to have been exterminated in the Scandinavian peninsula when the sudden appearance of a few animals in southern Sweden was reported in 1980. These wolves founded a new Swedish population which currently numbers at least 25 individuals, one of the world's smallest populations of the species. The sudden occurrence of the founder animals caused speculation that these had not appeared by 'natural' means but rather were Swedish zoo animals deliberately released by man. To analyse if this was the case and to elucidate the genetic status bi; this small and isolated population, we assessed nuclear and mitochondrial (mt) genetic variability in wild and captive grey wolves, using microsatellite typing and sequence analysis of the mtDNA D-loop. The new population was found to be monomorphic for a mtDNA haplotype which also was present in the Swedish zoo population. A total of four different mtDNA haplotypes were found among all captive and wild wolves (including two animals from an occasional establishment of a few wolves in northern Sweden in the late 1970s), with a maximum sequence divergence of 3.1 %. Despite the mtDNA congruence, animals from the zoo population could most likely be excluded as founders for the wild population since the latter group of animals displayed several unique microsatellite alleles (i.e. alleles not found in the zoo population). Moreover, a phylogenetic analysis of individual wolves, using microsatellite allele sharing as distance measure, placed all wild animals on a branch separated from that of the captive animals. The average degree of nuclear variability as well as allelic diversity was similar in the wild and the captive populations, respectively, but was lower than that reported for North-American populations of grey wolves. Polymorphism has declined in wild wolves born in recent years suggesting that this small population is currently suffering from a loss of genetic variability due to inbreeding. Inbreeding depression is documented in captive wolves and the long-term survival of the wild Swedish population may therefore depend on immigration of animals from Russia. This study illustrates the usefulness of microsatellites for dissecting close genetic relationships and for addressing the genetic status of individuals.
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| 10. |
- Merilä, Juha, et al.
(författare)
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Antagonistic natural selection revealed by molecular sex identification of nestling collared flycatchers
- 1997
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Ingår i: Molecular Ecology. - 0962-1083 .- 1365-294X. ; 6:12, s. 1167-1175
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Tidskriftsartikel (refereegranskat)abstract
- Natural selection may act in different directions during different life-history stages, or in different directions on different classes of individuals. Antagonistic selection of this kind may be an important mechanism by which additive genetic variation for quantitative traits is maintained, and can prevent populations or species reaching local adaptive peaks. This paper reports the results of a study of viability selection on morphological traits of nestling collared flycatchers Ficedula albicollis. Analyses performed without knowledge of the sex of nestlings suggested that no selection was occurring on these traits. However, using molecular sex identification with the avian CHD gene, it is shown that selection acts in different directions on male and female body size from fledging to breeding, apparently favouring relatively small males and large females. The results suggest that differential selection on male and female nestlings may contribute to purely phenotypic sexual size dimorphism in this species. These findings highlight the potential of newly developed molecular sexing techniques to reveal the consequences of an individual's gender for many aspects of its life history in taxa where gender cannot be determined on the basis of external appearance.
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