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Träfflista för sökning "WFRF:(Hollestelle A) ;srt2:(2010-2014)"

Search: WFRF:(Hollestelle A) > (2010-2014)

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  • Orr, Nick, et al. (author)
  • Genome-wide association study identifies a common variant in RAD51B associated with male breast cancer risk
  • 2012
  • In: Nature Genetics. - : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 44:11, s. 1182-1184
  • Journal article (peer-reviewed)abstract
    • We conducted a genome-wide association study of male breast cancer comprising 823 cases and 2,795 controls of European ancestry, with validation in independent sample sets totaling 438 cases and 474 controls. A SNP in RAD51B at 14q24.1 was significantly associated with male breast cancer risk (P = 3.02 x 10(-13); odds ratio (OR) = 1.57). We also refine association at 16q12.1 to a SNP within TOX3 (P = 3.87 x 10(-15); OR = 1.50).
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