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Träfflista för sökning "WFRF:(Holmberg Eva) srt2:(2000-2004)"

Search: WFRF:(Holmberg Eva) > (2000-2004)

  • Result 1-10 of 18
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  • Holmberg, Johan, et al. (author)
  • Old Moving Groups
  • 2002
  • In: Modes of Star Formation and the Origin of Field Populations, ASP Conference Proceedings.. - 1583811281 ; 285, s. 188-194
  • Conference paper (peer-reviewed)
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  • Holmberg, Sara, et al. (author)
  • Psychosocial factors and low back pain, consultations, and sick leave among farmers and rural referents : A population-based study
  • 2004
  • In: Journal of Occupational and Environmental Medicine. - : Ovid Technologies (Wolters Kluwer Health). - 1076-2752 .- 1536-5948. ; 46:9, s. 993-998
  • Journal article (peer-reviewed)abstract
    • Farmers have more low back pain (LBP) than nonfarmers. In a previous report, we found that differences between farmers and nonfarmers in physical work exposure did not explain the LBP differences. In this report, we tested the hypothesis that psychosocial factors might explain the differences in LBP reporting, medical consultation, and sick leave. A cross-sectional population-based survey of 1,013 middle-aged farmers and 769 matched referents was performed. Data on LBP, consultations, and sick leave during lifetime was obtained along with information on psychosocial, social network, and lifestyle variables. Several of the psychosocial variables were associated with LBP but the difference in LBP prevalence between farmers and nonfarmers could be explained only marginally. Farmers and self-employed referents tended to have lower odds of sick leave because of LBP than employed referents after adjustment for psychosocial factors.
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  • Kainu, T, et al. (author)
  • Somatic deletions in hereditary breast cancers implicate 13q21 as a putative novel breast cancer susceptibility locus
  • 2000
  • In: Proceedings of the National Academy of Sciences. - 1091-6490. ; 97:17, s. 9603-9608
  • Journal article (peer-reviewed)abstract
    • A significant proportion of familial breast cancers cannot be explained by mutations in the BRCA1 or BRCA2 genes. We applied a strategy to identify predisposition loci for breast cancer by using mathematical models to identify early somatic genetic deletions in tumor tissues followed by targeted linkage analysis. Comparative genomic hybridization was used to study 61 breast tumors from 37 breast cancer families with no identified BRCA1 or BRCA2 mutations. Branching and phylogenetic tree models predicted that loss of 13q was one of the earliest genetic events in hereditary cancers. In a Swedish family with five breast cancer cases, all analyzed tumors showed distinct 13q deletions, with the minimal region of loss at 13q21-q22. Genotyping revealed segregation of a shared 13q21 germ-line haplotype in the family. Targeted linkage analysis was carried out in a set of 77 Finnish, Icelandic, and Swedish breast cancer families with no detected BRCA1 and BRCA2 mutations. A maximum parametric two-point logarithm of odds score of 2.76 was obtained for a marker at 13q21 (D13S1308, theta = 0.10). The multipoint logarithm of odds score under heterogeneity was 3.46. The results were further evaluated by simulation to assess the probability of obtaining significant evidence in favor of linkage by chance as well as to take into account the possible influence of the BRCA2 locus, located at a recombination fraction of 0.25 from the new locus. The simulation substantiated the evidence of linkage at D13S1308 (P < 0.0017). The results warrant studies of this putative breast cancer predisposition locus in other populations.
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  • Result 1-10 of 18
Type of publication
journal article (15)
reports (1)
conference paper (1)
book chapter (1)
Type of content
peer-reviewed (16)
other academic/artistic (2)
Author/Editor
Thelin, Anders (6)
Holmberg, Sara (6)
Svärdsudd, Kurt (5)
Hagfeldt, Anders (3)
Holmberg, Anna (3)
Boschloo, Gerrit (2)
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Holmberg, Eva (2)
Olsson, Håkan (1)
Eerola, Hannaleena (1)
Nevanlinna, Heli (1)
Heikkilä, Päivi (1)
Welinder-Olsson, Chr ... (1)
Holmberg, L (1)
Lenhoff, Stig (1)
Turesson, Ingemar (1)
Karlsson, M (1)
Holmberg, Johan (1)
Wahlström, Jan, 1939 (1)
Grönberg, Henrik (1)
Weaver, D. (1)
Carlson, Kristina (1)
Feltzing, Sofia (1)
Johannsson, Oskar (1)
Holmberg, Erik (1)
Björck-Åkesson, Eva (1)
Holm, M. (1)
Westbom, L (1)
Borg, Åke (1)
Kaijser, Bertil, 194 ... (1)
Holli, K (1)
Nygren, Anders (1)
Holmberg, Martin (1)
Eliasson, A C (1)
Risberg, Jan (1)
Hedling, Erik (1)
Holmberg, Claes-Göra ... (1)
Wesslén, Lars (1)
Friman, Göran (1)
Westin, Jan (1)
Syrjakoski, K (1)
Kallioniemi, O P (1)
Nordling, Margareta, ... (1)
Aranyos, Viviane (1)
Lindquist, Sten-Eric (1)
Figgemeier, Egbert (1)
Lanng Nielsen, Johan (1)
Vehmanen, Paula (1)
Egilsson, Valgardur (1)
Arason, A (1)
Gimsing, Peter (1)
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University
Uppsala University (11)
Lund University (3)
University of Gothenburg (2)
Umeå University (1)
Linköping University (1)
Jönköping University (1)
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Karolinska Institutet (1)
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Language
English (12)
Swedish (3)
Undefined language (3)
Research subject (UKÄ/SCB)
Natural sciences (3)
Medical and Health Sciences (3)
Humanities (2)

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