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Search: WFRF:(Howell A) > Research review > (2022)

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1.	Vega, J., et al. (author) Disruption prediction with artificial intelligence techniques in tokamak plasmas 2022 In: Nature Physics. - : Springer Science and Business Media LLC. - 1745-2481 .- 1745-2473. ; 18:7, s. 741-750 Research review (peer-reviewed)
2.	Overview of JET results for optimising ITER operation 2022 In: Nuclear Fusion. - : IOP Publishing. - 1741-4326 .- 0029-5515. ; 62:4 Research review (peer-reviewed)
3.	Heindel, Jerrold J., et al. (author) Obesity II : Establishing causal links between chemical exposures and obesity 2022 In: Biochemical Pharmacology. - : Elsevier. - 0006-2952 .- 1356-1839 .- 1873-2968. ; 199 Research review (peer-reviewed)abstract Obesity is a multifactorial disease with both genetic and environmental components. The prevailing view is that obesity results from an imbalance between energy intake and expenditure caused by overeating and insufficient exercise. We describe another environmental element that can alter the balance between energy intake and energy expenditure: obesogens. Obesogens are a subset of environmental chemicals that act as endocrine disruptors affecting metabolic endpoints. The obesogen hypothesis posits that exposure to endocrine disruptors and other chemicals can alter the development and function of the adipose tissue, liver, pancreas, gastrointestinal tract, and brain, thus changing the set point for control of metabolism. Obesogens can determine how much food is needed to maintain homeostasis and thereby increase the susceptibility to obesity. The most sensitive time for obesogen action is in utero and early childhood, in part via epigenetic programming that can be transmitted to future generations. This review explores the evidence supporting the obesogen hypothesis and highlights knowledge gaps that have prevented widespread acceptance as a contributor to the obesity pandemic. Critically, the obesogen hypothesis changes the narrative from curing obesity to preventing obesity.

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Type of publication: research review (3)Undo refine

Type of content: peer-reviewed (3)

Author/Editor: Griffiths, J. (2); Hayashi, T. (2); Jones, G. (2); Li, Y. (2); Nowak, S. (2); Price, D. (2); show more...; Silva, J. (2); Spagnolo, S. (2); Walker, R. (2); Yang, Y. (2); Gao, Y. (2); Martin, A. J. (2); Marshall, R. (2); Burgess, A (2); Kaufman, M (2); Taylor, D (2); Clark, M. (2); Oya, Y. (2); Robinson, S. (2); Nicassio, M. (2); Seo, J. (2); Schneider, M. (2); Foley, S. (2); Garcia, J. (2); Zhang, W. (2); West, A. (2); Wheeler, S. (2); Smith, P. (2); Morris, J. (2); Lee, S (2); Wood, R (2); Bowden, M. (2); Lewis, J (2); Svoboda, J (2); Ali, M (2); Gorini, G (2); Knight, M (2); Davies, A (2); Scott, M (2); Sridhar, S. (2); Rodrigues, P (2); Young, R. (2); Duran, I (2); Mayer, M. (2); Khan, K (2); Lopez, J. M. (2); Thomas, J. (2); Hjalmarsson, A. (2); Buckingham, R. (2); Fowler, C. (2); show less...

University: Royal Institute of Technology (2); Uppsala University (2); Chalmers University of Technology (2); Karolinska Institutet (1)

Language: English (3)

Research subject (UKÄ/SCB): Natural sciences (3); Engineering and Technology (2)

Year: 2022 (3)Undo refine

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