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Träfflista för sökning "WFRF:(Karlsson P) srt2:(1995-1999)"

Search: WFRF:(Karlsson P) > (1995-1999)

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  • Stenman, U H, et al. (author)
  • Summary report of the TD-3 workshop: characterization of 83 antibodies against prostate-specific antigen
  • 1999
  • In: Tumor Biology. - : Springer Science and Business Media LLC. - 1423-0380 .- 1010-4283. ; 20:Suppl. 1, s. 1-12
  • Journal article (peer-reviewed)abstract
    • Twelve research groups participated in the ISOBM TD-3 Workshop in which the reactivity and specificity of 83 antibodies against prostate-specific antigen (PSA) were investigated. Using a variety of techniques including cross-inhibition assays, Western blotting, BIAcore, immunoradiometric assays and immunohistochemistry, the antibodies were categorized into six major groups which formed the basis for mapping onto two- and three-dimensional (2-D and 3-D) models of PSA. The overall findings of the TD-3 Workshop are summarized in this report. In agreement with all participating groups, three main antigenic domains were identified: free PSA-specific epitopes located in or close to amino acids 86-91; discontinuous epitopes specific for PSA without human kallikrein (hK2) cross-reactivity located at or close to amino acids 158-163; and continuous or linear epitopes shared between PSA and hK2 located close to amino acids 3-11. In addition, several minor and partly overlapping domains were also identified. Clearly, the characterization of antibodies from this workshop and the location of their epitopes on the 3-D model of PSA illustrate the importance of selecting appropriate antibody pairs for use in immunoassays. It is hoped that these findings and the epitope nomenclature described in this TD-3 Workshop are used as a standard for future evaluation of anti-PSA antibodies.
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  • Result 1-10 of 213
Type of publication
journal article (171)
conference paper (33)
reports (5)
book chapter (3)
research review (1)
Type of content
peer-reviewed (157)
other academic/artistic (55)
pop. science, debate, etc. (1)
Author/Editor
Karlsson, P (47)
Farde, L (39)
Halldin, C (38)
Karlsson, L (23)
SWAHN, CG (23)
Sedvall, G (18)
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Baltzer, P (16)
Wannberg, B (16)
Kanski, J (13)
Karlsson, B (12)
Karlsson, Ulf O. (12)
Karlsson, E (11)
Karlsson, T (11)
Hall, H (11)
Karlsson, FA (11)
HOLLAND, DMP (10)
Lundqvist, M (9)
Nilsson, P. O. (9)
Ilver, L (8)
Karlsson, A. (8)
Suhara, T (8)
Roos, A. (8)
MACDONALD, MA (8)
Lundkvist, C (8)
Nostell, P (8)
Foged, C (7)
Hakansson, M C (7)
Nyberg, S (7)
Karlsson, H (7)
Nordstrom, AL (7)
Olsson, H. (6)
Laurell, Fredrik (6)
Henriksson, P (6)
Karlsson, S. (6)
Burman, P. (6)
Arvidsson, G (6)
Hayes, MA (6)
Nakashima, Y (6)
Karlsson, MO (5)
Larsson, S. (5)
Herlitz, Johan (5)
Karlsson, K (5)
Hiltunen, J (5)
Albertsson, P (5)
Karlsson, Anna, 1967 (5)
Andersson, C B M (5)
Olsson, L O (5)
Ginovart, N (5)
Karlson, BW (5)
Chou, YH (5)
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University
Karolinska Institutet (84)
Uppsala University (66)
Royal Institute of Technology (23)
University of Gothenburg (11)
Lund University (6)
University of Borås (6)
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Linköping University (5)
Karlstad University (5)
Umeå University (3)
University of Skövde (3)
Linnaeus University (2)
Högskolan Dalarna (2)
Marie Cederschiöld högskola (2)
Luleå University of Technology (1)
Mälardalen University (1)
Örebro University (1)
Mid Sweden University (1)
Chalmers University of Technology (1)
RISE (1)
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Language
English (208)
Swedish (5)
Research subject (UKÄ/SCB)
Medical and Health Sciences (20)
Natural sciences (19)
Engineering and Technology (5)
Social Sciences (1)

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