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Träfflista för sökning "WFRF:(Lee W. H.) srt2:(1995-1999)"

Sökning: WFRF:(Lee W. H.) > (1995-1999)

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  • Bower, K. N., et al. (författare)
  • The Great Dun Fell experiment 1995 : An overview
  • 1999
  • Ingår i: Atmospheric Research. - 0169-8095. ; 50:3-4, s. 151-184
  • Tidskriftsartikel (refereegranskat)abstract
    • During March and April of 1995 a major international field project was conducted at the UMIST field station site on Great Dun Fell in Cumbria, Northern England. The hill cap cloud which frequently envelopes this site was used as a natural flow through reactor to examine the sensitivity of the cloud microphysics to the aerosol entering the cloud and also to investigate the effects of the cloud in changing the aerosol size distribution, chemical composition and associated optical properties. To investigate these processes, detailed measurements of the cloud water chemistry (including the chemistry of sulphur compounds, organic and inorganic oxidised nitrogen and ammonia), cloud microphysics and properties of the aerosol and trace gas concentrations upwind and downwind of the cap cloud were undertaken. It was found that the cloud droplet number was generally strongly correlated to aerosol number concentration, with up to 2000 activated droplets cm-3 being observed in the most polluted conditions. In such conditions it was inferred that hygroscopic organic compounds were important in the activation process. Often, the size distribution of the aerosol was substantially modified by the cloud processing, largely due to the aqueous phase oxidation of S(IV) to sulphate by hydrogen peroxide, but also through the uptake and fixing of gas phase nitric acid as nitrate, increasing the calculated optical scattering of the aerosol substantially (by up to 24%). New particle formation was also observed in the ultrafine aerosol mode (at about 5 nm) downwind of the cap cloud, particularly in conditions of low total aerosol surface area and in the presence of ammonia and HCl gases. This was seen to occur at night as well as during the day via a mechanism which is not yet understood. The implications of these results for parameterising aerosol growth in Global Climate Models are explored.
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4.
  • Brinkman, M J, et al. (författare)
  • Decay from a superdeformed band in Pb-194
  • 1996
  • Ingår i: Physical Review C. Nuclear Physics. - 0556-2813 .- 1089-490X. ; 53:4, s. R1461-R1464
  • Tidskriftsartikel (refereegranskat)abstract
    • Three experiments using the (174) Yb(Mg-25,5n)Pb-194 reaction have been undertaken at the Early Implementation of Gammasphere to study the decay of known superdeformed states in Pb-194. A single discrete transition with an energy of 2.746(2) MeV carrying 6(2)% of the full superdeformed band intensity has been identified. A discussion of our results and the assignment of the 2.746-MeV transition as a discrete gamma ray directly connecting the superdeformed 8(+) and low-lying 6(+) levels will be presented.
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5.
  • Campieri, M, et al. (författare)
  • Oral budesonide is as effective as oral prednisolone in active Crohn's disease. The Global Budesonide Study Group
  • 1997
  • Ingår i: Gut. - : BMJ. - 0017-5749 .- 1468-3288. ; 41:2, s. 209-214
  • Tidskriftsartikel (refereegranskat)abstract
    • Background—The use of corticosteroids in active Crohn’s disease often becomes limited by side effects. Budesonide is a potent corticosteroid with low systemic bioavailability due to an extensive first pass liver metabolism.Aims—To compare the efficacy and safety of two dosage regimens of budesonide and prednisolone in patients with active Crohn’s disease affecting the ileum and/or the ascending colon.Patients and methods—One hundred and seventy eight patients were randomised to receive budesonide controlled ileal release (CIR) capsules 9 mg once daily or 4.5 mg twice daily, or prednisolone tablets 40 mg once daily. The treatment period was 12 weeks. The primary efficacy variable was clinical remission, defined as a Crohn’s Disease Activity Index (CDAI) of 150 or less.Results—After eight weeks of treatment, remission occurred in 60% of patients receiving budesonide once daily or prednisolone and in 42% of those receiving budesonide twice daily (p=0.062). The presence of glucocorticoid associated side effects was similar in all groups; however, moon face was more common in the prednisolone group (p=0.0005). The highest frequency of impaired adrenal function, as measured by a short ACTH test, was found in the prednisolone group (p=0.0023).Conclusions—Budesonide CIR, administered at 9 mg once daily or 4.5 mg twice daily, is comparable to prednisolone in inducing remission in active Crohn’s disease. The single dose administration is as promptly effective as prednisolone and represents a simpler and safer therapeutic approach, with a considerable reduction in side effects.
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  • Hjelle, B, et al. (författare)
  • Rapid and specific detection of Sin Nombre virus antibodies in patients with hantavirus pulmonary syndrome by a strip immunoblot assay suitable for field diagnosis.
  • 1997
  • Ingår i: Journal of Clinical Microbiology. - 0095-1137 .- 1098-660X. ; 35:3, s. 600-8
  • Tidskriftsartikel (refereegranskat)abstract
    • To develop a rapid antibody test for Sin Nombre hantavirus (SNV) infection for diagnosis of hantavirus pulmonary syndrome (HPS) in field settings where advanced instrumentation is not available, a strip immunoblot assay bearing four immobilized antigens for SNV and a recombinant nucleocapsid protein antigen of Seoul hantavirus (SEOV) was prepared. The SNV antigens included a full-length recombinant-expressed nucleocapsid (N) protein (rN), a recombinant-expressed G1 protein (residues 35 to 117), and synthetic peptides derived from N (residues 17 to 59) and G1 (residues 55 to 88). On the basis of the observed reactivities of hantavirus-infected patient and control sera, we determined that a positive assay requires reactivity with SNV or SEOV rN antigen and at least one other antigen. Isolated reactivity to either viral rN antigen is indeterminate, and any pattern of reactivity that does not include reactivity to an rN antigen is considered indeterminate but is unlikely to represent hantavirus infection. Fifty-eight of 59 samples from patients with acute SNV-associated HPS were positive according to these criteria, and one was initially indeterminate. Four of four samples from patients with HPS due to other hantaviruses were positive, as were most samples from patients with SEOV and Puumala virus infections. Of 192 control serum samples, 2 (1%) were positive and 2 were indeterminate. Acute SNV infection was distinguishable from remote SNV infection or infection with hantaviruses other than SNV by the presence of G1 peptide antigen reactivities in the former. The strip immunoblot assay shows promise for the detection of SNV antibodies early in the course of HPS.
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8.
  • LaFosse, D R, et al. (författare)
  • Search for hyperdeformation in Gd-146,Gd-147
  • 1996
  • Ingår i: Physical Review C. Nuclear Physics. - 0556-2813 .- 1089-490X. ; 54:4, s. 1585-1588
  • Tidskriftsartikel (refereegranskat)abstract
    • A search was undertaken to look for evidence of hyperdeformation in Gd-146,Gd-147. Three experiments employing Gammasphere for gamma-ray detection coupled with the Microball for channel selection via charged particle detection were carried out with increasing detection sensitivity and statistics. No definitive evidence for band structures that could be assigned to hyperdeformation could be found. Candidates previously reported are shown not to have properties consistent with a band structure.
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9.
  • McNabb, D P, et al. (författare)
  • Superdeformation in Po-198
  • 1996
  • Ingår i: Physical Review C. Nuclear Physics. - 0556-2813 .- 1089-490X. ; 53:2, s. R541-R543
  • Tidskriftsartikel (refereegranskat)abstract
    • The Yb-174(Si-29,5n) reaction at 148 MeV with thin targets was used to populate high-angular momentum states in Po-198. Resulting gamma rays were observed with Gammasphere. A weakly populated superdeformed band of 10 gamma-ray transitions was found and has been assigned to Po-198. This is the first observation of an SD band in the A approximate to 190 region in a nucleus with Z > 83. The J((2))) of the new band is very similar to those of the yrast SD bands in Hg-194 and Pb-196. The intensity profile suggests that this band is populated through states close to where the SD band crosses the yrast line and the angular momentum at which the fission process dominates.
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10.
  • Svensson, C. E., et al. (författare)
  • Decay Out of the Doubly Magic Superdeformed Band in the N=Z Nucleus 60Zn
  • 1999
  • Ingår i: Physical Review Letters. - 1079-7114. ; 82:17, s. 3400-3403
  • Tidskriftsartikel (refereegranskat)abstract
    • The doubly magic superdeformed band in the N = Z nucleus Zn-60 has been identified. Linking transitions connecting this band to the yrast line provide the first spin, parity, and excitation energy measurements for superdeformed states in the A similar to 60 region. The stretched-E2 character and relatively large B(E2) values of these transitions suggest a nonstatistical decay-out process.
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