SwePub
Sök i SwePub databas

  Utökad sökning

Träfflista för sökning "WFRF:(Lester J) srt2:(2020-2021)"

Sökning: WFRF:(Lester J) > (2020-2021)

  • Resultat 1-10 av 16
Sortera/gruppera träfflistan
   
NumreringReferensOmslagsbildHitta
1.
  • 2021
  • swepub:Mat__t
  •  
2.
  • 2021
  • swepub:Mat__t
  •  
3.
  • Glasbey, JC, et al. (författare)
  • 2021
  • swepub:Mat__t
  •  
4.
  •  
5.
  •  
6.
  •  
7.
  •  
8.
  • Coignard, J, et al. (författare)
  • A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers
  • 2021
  • Ingår i: Nature communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 12:1, s. 1078-
  • Tidskriftsartikel (refereegranskat)abstract
    • Breast cancer (BC) risk for BRCA1 and BRCA2 mutation carriers varies by genetic and familial factors. About 50 common variants have been shown to modify BC risk for mutation carriers. All but three, were identified in general population studies. Other mutation carrier-specific susceptibility variants may exist but studies of mutation carriers have so far been underpowered. We conduct a novel case-only genome-wide association study comparing genotype frequencies between 60,212 general population BC cases and 13,007 cases with BRCA1 or BRCA2 mutations. We identify robust novel associations for 2 variants with BC for BRCA1 and 3 for BRCA2 mutation carriers, P < 10−8, at 5 loci, which are not associated with risk in the general population. They include rs60882887 at 11p11.2 where MADD, SP11 and EIF1, genes previously implicated in BC biology, are predicted as potential targets. These findings will contribute towards customising BC polygenic risk scores for BRCA1 and BRCA2 mutation carriers.
  •  
9.
  •  
10.
  • Stergiopoulou, Katerina, et al. (författare)
  • Mars Express Observations of Cold Plasma Structures in the Martian Magnetotail
  • 2020
  • Ingår i: Journal of Geophysical Research - Space Physics. - : American Geophysical Union (AGU). - 2169-9380 .- 2169-9402. ; 125:10
  • Tidskriftsartikel (refereegranskat)abstract
    • We present observations from five Mars Express (MEX) orbits in September 2016 while the spacecraft passed through the Martian induced magnetotail at altitudes up to 3,500 km. On these orbits, the Mars Advanced Radar for Subsurface and Ionosphere Sounding (MARSIS) instrument was operated in Active Ionospheric Sounding (AIS) mode at much higher altitude than normal, acting as a local sounder and detecting cold plasma structures in this region. In this paper we combine MARSIS tail measurements with solar wind data from the Solar Wind Ion Analyzer (SWIA) instrument and the Magnetometer (MAG) from Mars Atmosphere and Volatile EvolutioN (MAVEN) in order to investigate possible factors affecting plasma transport from the dayside and through the terminator. MARSIS observed structured cold ionospheric plasma along its trajectory, at all altitudes and solar zenith angles (SZAs). Isolated regions of cold plasma were also observed on each orbit as the spacecraft crossed the terminator, even at high altitudes. We conclude that the variability of plasma seen in the tail results from a multifactorial transport process, the development of which cannot be attributed to a sole parameter influencing it, despite the availability of simultaneous high quality solar wind measurements.
  •  
Skapa referenser, mejla, bekava och länka
  • Resultat 1-10 av 16

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy