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Detectable Vesicular Stomatitis Virus (VSV)-Specific Humoral and Cellular Immune Responses Following VSV-Ebola Virus Vaccination in Humans

Poetsch, JH (author)
Dahlke, C (author)
Zinser, ME (author)
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Kasonta, R (author)
Lunemann, S (author)
Rechtien, A (author)
Ly, ML (author)
Stubbe, HC (author)
Kraehling, V (author)
Biedenkopf, N (author)
Eickmann, M (author)
Fehling, SK (author)
Olearo, F (author)
Strecker, T (author)
Sharma, P (author)
Lang, KS (author)
Lohse, AW (author)
Schmiedel, S (author)
Becker, S (author)
Siegrist, CA (author)
Huttner, A (author)
Addo, MM (author)
Bejon, P (author)
Njuguna, P (author)
Ndungu, F (author)
Karolinska Institutet
Kremsner, PG (author)
Brosnahan, JS (author)
Agnandji, ST (author)
Krishna, S (author)
Kieny, MP (author)
Modjarrad, K (author)
Moorthy, V (author)
Fast, P (author)
Savarese, B (author)
Lapujade, O (author)
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 (creator_code:org_t)
2018-11-17
2019
English.
In: The Journal of infectious diseases. - : Oxford University Press (OUP). - 1537-6613 .- 0022-1899. ; 219:4, s. 556-561
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • This study investigates preexisting and vaccine-induced vector immunity in 30 participants of a Phase-1 VSV-EBOV Ebola vaccine trial. No preexisting immunity was detected, however humoral and cell-mediated immunity against internal VSV proteins was observed in up to 36% of vaccines.

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