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Träfflista för sökning "WFRF:(Shaw P) ;lar1:(liu);srt2:(2007-2009)"

Search: WFRF:(Shaw P) > Linköping University > (2007-2009)

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1.	Murphy, Shaun P, et al. (author) Evidence for participation of uterine natural killer cells in the mechanisms responsible for spontaneous preterm labor and delivery 2009 In: AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY. - : Elsevier BV. - 0002-9378. ; 200:3, s. 308.e1-308.e9 Journal article (peer-reviewed)abstract OBJECTIVE: The purpose of this study was to determine in a mouse model whether uterine natural killer (uNK) cell cytotoxic activation induces infection/inflammation-associated preterm labor and delivery. STUDY DESIGN: Wild type or interleukin (IL)-10(-/-) mice were injected intraperitoneally with lipopolysaccharide on gestational day 14. Mice were either killed for collection of uteroplacental tissue, spleen, and serum or allowed to deliver. Uteroplacental tissue was used for histology and characterization of uNK cells. RESULTS: Low-dose lipopolysaccharide treatment triggered preterm labor and delivery in IL-10(-/-), but not wild type mice, in a manner independent of progesterone levels. Preterm labor and delivery in IL-10(-/-) mice was associated with an increased number and placental infiltration of cytotoxic uNK cells and placental cell death. Depletion of NK cells or tumor necrosis factor (TNF)-alpha neutralization in these mice restored term delivery. Furthermore, TNF-alpha neutralization prevented uNK cell infiltration and placental cell apoptosis. CONCLUSION: The uNK cell-TNF-alpha-IL-10 axis plays an important role in the genesis of infection/inflammation-induced pretermlabor/delivery.
2.	Pearce, Ruth, 1982-, et al. (author) The effect of temperature on the gas sensing properties of CVD grown MWCNTs 2007 In: The 2nd Conference onf Sensing Technology ICST, 2007. - Palmerston North, New Zeeland : Palmerston Inst. of Information Sciences and Techn., Massey University.. - 9780473124328 ; , s. 455-460 Conference paper (peer-reviewed)

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Type of publication: journal article (1); conference paper (1)

Type of content: peer-reviewed (2)

Author/Editor: Berg, Göran (1); Sharma, Surendra (1); Andersson, Mike, 197 ... (1); Lloyd Spetz, Anita, ... (1); Romero, Roberto (1); Shaw, J (1); show more...; Buchholt, Kristina, ... (1); Murphy, Shaun P (1); Hanna, Nazeeh N (1); Fast, Loren D (1); Shaw, Sunil K (1); Padbury, James F (1); Pearce, Ruth, 1982- (1); Belmonte, Judith (1); Schaffer, M S P (1); show less...

University: Linköping University (2)Undo refine

Language: English (2)

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