| 1. |
- Aalto, Mikko, et al.
(author)
-
Viskeraalinen leishmaniaasi tunnistamattomana tappavana tautina : [Visceral leishmaniasis as an unrecognized deadly disease]
- 2023
-
In: Duodecim. - : Finnish Medical Society Duodecim. - 0012-7183 .- 2242-3281. ; 139:11, s. 885-891
-
Journal article (peer-reviewed)abstract
- Visceral leishmaniasis is a disease caused by Leishmania parasites and transmitted by Phlebotomine sandflies. It affects primarily children and is fatal without treatment but curable with early treatment. Its clinical features are prolonged fever, wasting, hepatosplenomegaly and pancytopenia. Doctors have limited knowledge about its diagnostics. This leads to incorrect diagnoses and deaths, and the disease remains unrecognized. To break this vicious circle, active search of the disease is needed also where environmental factors are conductive to its presence, but it has never been reported. We describe discovering new foci of visceral leishmaniasis in Northern Somalia, Somaliland and Tanzania.
|
|
| 2. |
- Aikomus, L., et al.
(author)
-
Työn fyysisen kuormittavuuden yhteys fyysiseen toimintakykyyn alle 40-vuotiailla kunta-alan työntekijöillä [Associations between physically demanding work and physical functioning among municipal employees under 40 years of age]
- 2021
-
In: SOSIAALILÄÄKETIETEELLINEN AIKAKAUSLEHTI. - 0355-5097. ; 58, s. 445-456
-
Journal article (peer-reviewed)abstract
- Physically demanding work in middle-aged and ageing employees is associated with poor physical functioning. Also younger employees have limitations in their daily functioning, but there is no research on the associations between physically demanding work and physical functioning during early careers. This study investigated whether physically demanding work is associated with physical functioning in employees aged 18–39 years. The data were collected in autumn 2017 from the City of Helsinki employees born in or after 1978 (n=11,459). Out of them, 5,111 responded online or via a mailed paper survey. We included those 4,585 (40% of all those invited) who had responded to all necessary questions for the present study. Physical functioning was assessed by the SF-36 questionnaire, and poor physical functioning was defined as the lowest quarter of the physical functioning score (PCS ≤48.80, total scale 1-100). Physical workload was determined with a multi-part question about factors related to work and the work environment, and the degree of perceived harm caused by them. The physical workload scores were divided into thirds. Logistic regression analysis was used to examine the associations between physically demanding work and physical functioning, while adjusting for health behaviours, sleep problems, body mass index, education and marital status. Poor physical functioning was associated with physically moderately (OR 1.70, 95%CI 1.43-2.00) and highly (OR 3.56 [2.70-4.70]) demanding work. In addition, frequent sleep problems (OR 1.90 [1.67-2.22]), obesity (OR 1.89 [1.56-2.30]) and low education (OR 1.37 [1.10-1.71]) were associated with poor physical functioning. Tackling physically demanding work may play a role in maintaining physical functioning (and subsequently) working capacity.Keywords: physical functioning, work load, young workers, health behaviour
|
|
| 3. |
|
|
| 4. |
|
|
| 5. |
|
|
| 6. |
|
|
| 7. |
|
|
| 8. |
|
|
| 9. |
- Alerby, Eva, et al.
(author)
-
Lasten hyvinvointi ell – näkökulmia aiheeseen
- 2008
-
In: Psykososiaalisen hyvinvoinnin edistäminen opetustyössä. - Rovaniemi : Lapin yliopistokustannus. - 9789524842280 ; , s. 39-46
-
Book chapter (other academic/artistic)
|
|
| 10. |
- Arokoski, Jari, et al.
(author)
-
Nivelrikon etiopatogeneesi [Etiopathogenesis of osteoarthritis].
- 2001
-
In: Duodecim. - : Duodecim. - 0012-7183 .- 2242-3281. ; 117:16, s. 1617-1626
-
Journal article (peer-reviewed)abstract
- Nivelrikon patofysiologia tunnetaan huonosti. Nykykäsityksen mukaan artroosissa ei olekyse nivelruston passiivisesta kulumisesta vaan biokemiallisesta tapahtumasarjasta, jossasoluväliaineen tuhoutuminen saa ylivallan rustoa korjaavista prosesseista. Nivelrikon alkuvaiheessarustosoluissa eli kondrosyyteissä aktivoituvat sekä ruston aineosien synteesitoimintaettä rustoa hajottavien entsyymien ilmentyminen ja niitä koodaavien geenientoiminta. Nivelrikko on koko nivelen sairaus, joka aiheuttaa muutoksia niin nivelrustossa,luussa kuin pehmytosissakin. Vallitsevan käsityksen mukaan nivelrikko käynnistyynivelruston pinnallisesta vyöhykkeestä. On myös esitetty, että nivelalueen altistuminenliialliselle kuormitukselle aiheuttaisi ensin rustonalaisen luun paksunemisen ja jäykkenemisen,mikä puolestaan altistaisi nivelruston suuremmille kuormittaville voimille. Riskitekijöistätärkeimpiä ovat ikääntyminen, liikapaino, niveleen kohdistuvat vammat ja ruumiillisentyön aiheuttama liikarasitus. Perinnöllisten tekijöiden osuus on myös merkittävä.Ruston kollageenien rakennevirheiden tiedetään altistavan nivelrikolle.
|
|
