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Sökning: hsv:(MEDICIN OCH HÄLSOVETENSKAP) hsv:(Hälsovetenskap) > Annan publikation

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1.
  • Oscarson, Mats, 1939 (författare)
  • Emeriti 23 — Vetenskapens seniorer om forskningen, karriären och livet
  • 2017
  • Annan publikation (övrigt vetenskapligt/konstnärligt)abstract
    • Ny forskning om engelska språket i daglig kommunikation och neonatologins (nyföddhetslärans) makalösa utveckling under senare årtionden. EMERITI, program nr 23, gästas av Karin Aijmer, professor emerita i engelska, samt Ingemar Kjellmer, professor emeritus i pediatrik. Programledare är Mats Oscarson, professor emeritus i pedagogik. /// This Swedish language publication is a video recorded conversation on research and development issues in two academic disciplines at the University of Gothenburg, Sweden, i.e. English and Neonathology. Participants are Dr Karin Aijmer, professor emerita in English, Dr Ingemar Kjellmer, professor emeritus in pediatrics, particularly neonathology, and Dr Mats Oscarson, professor emeritus in education, also chair of the discussion and producer of the video manuscript.
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  • Groglopo, Adrián, 1967 (författare)
  • Integrationens svarta bok och akademins vita murar - Intervju med professor Masoud Kamali
  • 2019
  • Ingår i: Antirasistiska Akademin.
  • Annan publikation (övrigt vetenskapligt/konstnärligt)abstract
    • Masoud Kamali är professor i social arbete vid Mittuniversitetet, och mest känd från att ha lett den statliga utredningen om makt, integration och strukturell diskriminering som pågick 2004-2006 och som publicerade 13 volymer samt slutbetänkandet ”Integrationens svarta bok” (SOU 2006:79). Intervjuserie som finansierades av Myndigheten för ungdoms- och civilsamhällsfrågor. Projektet handlar om 17 djupintervjuer med både forskare som studerar rasism i Sverige och aktivister som arbetar med frågor om rasism och mänskliga rättigheter. Projektansvarig och intervjuare: Adrián Groglopo.
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  • Rejnö, Åsa, 1970-, et al. (författare)
  • Combining Qualitative and Quantitative Content Analysis : A Way to Utilize Different Types of Data in Research of Ethical Problems in Acute Stroke Care
  • 2017
  • Ingår i: Sage Research Methods. - 1 Oliver's Yard, 55 City Road, London EC1Y 1SP United Kingdom  : Sage Publications. - 9781526424877
  • Annan publikation (refereegranskat)abstract
    • Most people who experience an acute stroke survive, but a substantial number die as a result of it. Stroke is, according to the World Health Organization, the second leading cause of death globally. Research in the area of stroke has previously been less focused on situations when patients die due to an acute stroke in favor of research on medical treatments, rehabilitation, and living with the aftermath of stroke. Research focusing on ethical problems in the care of dying patients can be found both in general and in specific care contexts such as palliative, intensive, and non-hospital care, but knowledge concerning ethical problems in the area of stroke, or arising as a result of acute stroke, was lacking. Both these subjects, death due to acute stroke and ethical problems, were combined for the first author's (Å. R.) thesis. Individual interviews with stroke team members were performed guided by their answers in a three-part form filled out before the interviews. This case study provides an account of how qualitative and quantitative content analysis was used in combination to deepen the results from the study utilizing data obtained from both the three-part forms and the interviews performed. The case highlights some challenges faced when combining the two different types of data. It also gives examples of how the analysis was performed when combining qualitative and quantitative content analysis to support and further explore data.
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  • Albrecht, Lisa M, et al. (författare)
  • Cross-Resistance to Antibiotics After Exposure to Qaternary Ammonium Compounds
  • Annan publikation (övrigt vetenskapligt/konstnärligt)abstract
    • Quaternary ammonium compounds (QACs) are common antimicrobials that are used in a variety of consumer products, such as lotions, sunscreen, hair conditioners and hand sanitizers, to inhibit bacterial growth. However, it has been noted that bacteria exposed to QACs can develop resistance, and additionally, resistance to QACs has been observed to provide cross-resistance to antibiotics. In order to identify genetic adaptations for this resistance pattern, we exposed E. coli to three different QACs at sub-MIC and above-MIC concentrations, and identified genetic changes by whole genome sequencing. We found that initial adaptation, at sub-MIC levels, happened through efflux mechanisms, and that subsequent genetic changes, during above-MIC exposure, involved genes associated with the cell membranes and with transcription/translation. We also found that these genetic changes provided cross-resistance to other QACs as well as to several antibiotics.
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  • Albrecht, Lisa M, et al. (författare)
  • Mutation in the Copper-Induced sil Operon Enables High-Level Silver Resistance and Silver Facilitated Co-Selection of Multidrug Resistance Plasmid
  • Annan publikation (övrigt vetenskapligt/konstnärligt)abstract
    • Human activities are responsible for an accumulation of metals in health care and agricultural environments, and plasmid-encoded metal tolerance operons enable bacteria to rapidly adapt to metal exposure under such conditions. While the mechanisms of action of many metal resistance systems have been described, there is still limited understanding of their role in co-selection of antibiotic resistance in metal-containing environments. Whether plasmid-encoded metal resistance genes confer significant selective advantages is of interest as it has implications for plasmid enrichment and the spread of plasmid-borne antibiotic resistance genes. To increase our understanding of plasmid-mediated metal resistance, we studied the sil operon and its phenotypes in E. coli during growth in the absence and presence of silver and copper. We found that the sil operon provides resistance to both silver and copper. However, it is induced by copper only, and constitutive expression due to point mutations in the two-component silS gene provides high-level silver resistance. Furthermore, we showed that a high-level silver resistant mutant could be enriched in the presence of silver. This enrichment entailed co-selection of the multidrug resistance plasmid pUUH239.2. Our results show that a copper resistance operon can provide high-level silver resistance following a single point mutation, and that the silver resistance phenotype subsequently can co-select for antibiotic resistance in the presence of silver. 
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