| 1. |
- Magnusson, J, et al.
(författare)
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A kinetic study in adults with food hypersensitivity assessed as eosinophil activation in fecal samples
- 2003
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Ingår i: Clinical and Experimental Allergy. - : Wiley. - 0954-7894 .- 1365-2222. ; 33:8
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: Immune-mediated food hypersensitivity affecting the gut is difficult to evaluate, and objective tools to diagnose local gastrointestinal (GI) inflammatory reactions are lacking. OBJECTIVES: To determine whether allergic manifestations in adults with a history of food-related GI symptoms could be assessed in feces during symptomatic and non-symptomatic periods, using the surrogate markers, eosinophil cationic protein (ECP), eosinophil protein X (EPX) and myeloperoxidase (MPO). METHODS: Thirteen subjects with food hypersensitivity-related GI symptoms, confirmed by a positive double-blind placebo-controlled food challenge (DBPCFC), were subjected to an open kinetic food challenge design for 6 weeks. Symptoms were recorded and scored during the 3-week study period and stool samples were obtained every day. The surrogate markers ECP, EPX and MPO were measured in the supernatants from feces samples. RESULTS: A significant increase in abdominal pain, distension and flatulence was observed during challenge, with a gradual decrease during elimination diet. Both between days and subjects, EPX levels were more frequently increased compared to ECP and MPO. Individuals with a history of a short duration of symptoms had significantly higher mean levels of EPX and MPO than those with a longer duration of symptoms. CONCLUSIONS: An overall increase in levels of eosinophil markers, in particular EPX, was observed in feces from patients with food-related GI symptoms. However, rather than being a tool to differentiate symptomatic from non-symptomatic periods, EPX might be used for detecting an ongoing clinical or subclinical chronic inflammation, that may have an impact on the patient's clinical course of GI symptoms.
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| 2. |
- Berndtsson, Ina
(författare)
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Stoma-related complications after stoma construction in emergency surgery.
- 2009
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Ingår i: 10th European congress for nurses with interest in stomacare. Portugal, Porto, June 14-17, 2009..
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Konferensbidrag (refereegranskat)abstract
- PURPOSE; Prospectively longitudinal study of the frequency and type of stoma-related complications after stoma construction in emergency surgery. METHOD; 153 patients were operated acutely with a colostomy, ileostomy or loop-ileostomy formation between April 2003 and March 2005 at the Sahlgrenska University Hospital in Gothenburg, Sweden. The postoperative follow up took place in the ward and another five times two years after discharge. On these occasions diameter, height and shape of the ostomy were recorded. Peristomal skin problems, necrosis, leakage due to low ostomy, stenosis, granuloma, prolapse and peristomal hernia were evaluated. Use of convexity appliance was also documented. RESULTS were based on 144 patients 85 women and 59 men with a median age of 67 (range 23-98) years. The ostomy diameter size was postoperatively on the ward median 34 (r 22-80) mm but had reduced to 25 (r 22-60) mm in two weeks. Postoperatively on the ward 31% of colostomy was oval, and 24% of the ileostomy. After 12 months was 21% of the colostomy oval. Irrespective of ostomy types the most common complication was skin problems, most frequent in those with loop ileostomy (48%) hernia was most common in patients with colostomy (26%) at 12 months of follow-up. A patient may have developed more complications such as necrosis of stomin as the cause of this even skin problems. The patients with ileostomy used convexity appliance common in 6 month (67%) and the patients with colostomy in one year (29%). CONCLUSION This study shows that while skin problems dominated in ileostomy patients (48% in loop ileostomies) peristomal hernia was the most common complication in colostomy patients (26%). Early stoma nurse assistance in the acute phase and regular postoperative follow-up subsequently is very important.
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| 3. |
- Carlsson, Eva, et al.
(författare)
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Stomibandagering
- 2008. - 1
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Ingår i: Stomi- och tarmopererad : ett helhetsperspektiv - ett helhetsperspektiv. - Lund : Studentlitteratur. - 9789144047478 ; , s. 69-81
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Bokkapitel (övrigt vetenskapligt/konstnärligt)
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