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Search: hsv:(MEDICIN OCH HÄLSOVETENSKAP) hsv:(Klinisk medicin) hsv:(Geriatrik) > Luleå University of Technology > Soininen Hilkka > The effect of adher...

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The effect of adherence on cognition in a multidomain lifestyle intervention (FINGER)

Ngandu, Tiia (author)
Karolinska Institutet
Lehtisalo, Jenni (author)
Department of Public Health and Welfare, Population Health Unit, Finnish Institute for Health and Welfare, Helsinki, Finland; Institute of Clinical Medicine/Neurology, University of Eastern Finland, Kuopio, Finland
Korkki, Saana (author)
Karolinska Institutet
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Solomon, Alina (author)
Karolinska Institutet
Coley, Nicola (author)
Faculté de Médecine, INSERM-University of Toulouse UMR1295 (CERPOP), Toulouse, France; Department of Epidemiology and Public Health, Toulouse University Hospital, Toulouse, France,University Toulouse, FRA; Toulouse University Hospital, FRA
Antikainen, Riitta (author)
Center for Life Course Health Research, University of Oulu, Oulu, Finland; Medical Research Center Oulu, Oulu University Hospital, Oulu, Finland
Bäckman, Lars (author)
Karolinska Institutet
Hänninen, Tuomo (author)
Neurocenter, Department of Neurology, Kuopio University Hospital, Kuopio, Finland,Kuopio University Hospital, FIN
Lindström, Jaana (author)
Department of Public Health and Welfare, Population Health Unit, Finnish Institute for Health and Welfare, Helsinki, Finland
Laatikainen, Tiina (author)
Department of Public Health and Welfare, Population Health Unit, Finnish Institute for Health and Welfare, Helsinki, Finland; Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland; Joint municipal authority for North Karelia social and health services (Siun sote), Joensuu, Finland,Finnish Institute of Heallth & Welfare, FIN; University Eastern Finland, FIN; Joint Municipal Author North Karelia Social & Health, FIN
Paajanen, Teemu (author)
Finnish Institute of Occupational Health, Helsinki, Finland,Finnish Institute of Occupational Health, FIN
Havulinna, Satu (author)
Department of Public Health and Welfare, Functioning and Service Needs Unit, Finnish Institute for Health and Welfare, Helsinki, Finland
Peltonen, Markku (author)
Department of Public Health and Welfare, Population Health Unit, Finnish Institute for Health and Welfare, Helsinki, Finland; Division of Clinical Geriatrics, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Solna, Stockholm, Sweden
Stigsdotter Neely, Anna, 1961- (author)
Karlstads universitet,Luleå tekniska universitet,Hälsa, medicin och rehabilitering,Department of Social Psychological Sciences, Karlstad University, Karlstad, Sweden,Institutionen för sociala och psykologiska studier (from 2013),Luleå universitet
Strandberg, Timo (author)
Center for Life Course Health Research, University of Oulu, Oulu, Finland; Department of Medicine, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland
Tuomilehto, Jaakko (author)
Department of Public Health and Welfare, Population Health Unit, Finnish Institute for Health and Welfare, Helsinki, Finland; Department of Public Health, University of Helsinki, Helsinki, Finland; Diabetes Research Group, King Abdulaziz University, Jeddah, Saudi Arabia; South Ostrobothnia Central Hospital, Seinäjoki, Finland
Soininen, Hilkka (author)
Institute of Clinical Medicine/Neurology, University of Eastern Finland, Kuopio, Finland; Neurocenter, Department of Neurology, Kuopio University Hospital, Kuopio, Finland,University Eastern Finland, FIN; Kuopio University Hospital, FIN
Kivipelto, Miia (author)
Karolinska Institutet
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 (creator_code:org_t)
2021-10-20
2022
English.
In: Alzheimer's & Dementia. - : John Wiley & Sons. - 1552-5260 .- 1552-5279. ; 18:7, s. 1325-1334
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • Introduction: Lifestyle interventions may prevent cognitive decline, but the sufficient dose of intervention activities and lifestyle changes is unknown. We investigated how intervention adherence affects cognition in the FINGER trial (pre-specified subgroup analyses).Methods: FINGER is a multicenter randomized controlled trial examining the efficacy of multidomain lifestyle intervention (ClinicalTrials.gov NCT01041989). A total of 1260 participants aged 60 to 77 with increased dementia risk were randomized to a lifestyle intervention and control groups. Percentage of completed intervention sessions, and change in multidomain lifestyle score (self-reported diet; physical, cognitive, and social activity; vascular risk) were examined in relation to change in Neuropsychological Test Battery (NTB) scores.Results: Active participation was associated with better trajectories in NTB total and all cognitive subdomains. Improvement in lifestyle was associated with improvement in NTB total and executive function.Discussion: Multidomain lifestyle changes are beneficial for cognitive functioning, but future interventions should be intensive enough, and supporting adherence is essential.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Neurologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Neurology (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Geriatrik (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Geriatrics (hsv//eng)

Keyword

cognition
lifestyle
multidomain
prevention
Teknisk psykologi
Engineering Psychology
Psykologi inr. medicinsk psykologi

Publication and Content Type

ref (subject category)
art (subject category)

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