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| 2. |
- Juarez, Sol Pia
(författare)
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Calidad de los datos del Instituto Nacional de Estadística para la elaboración de los indicadores de salud perinatal: pequeño y grande para su edad gestacional
- 2015
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Ingår i: Revista Española de Salud Pública. - 1135-5727. ; 89:1, s. 85-91
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Tidskriftsartikel (refereegranskat)abstract
- Background: Relative measures of birthweight (small and large-for-gestational age, SGA-LGA) are increasingly preferred to absolute measures (low birthweight, macrosomia). In this study we assess whether the national vital statistics provided by the Spanish National Statistical Institute (INE) reliably estimate SGA and LGA. Also, we will assess whether missing data (selection) and misreported information (bias) are systematically associated with parental socioeconomic information. Methods: We linked the information on 6,339 births at the Hospital Clinico San Carlos of Madrid (2005-06) with the vital statistics records (successful for the 95% of the observation). Validity measures and concordance were estimated for low birthweight (LBW, <2500 gr), macrosomia (>4500 gr), SGA (<10th percentile) and LGA (>90 percentile). Logistic regressions were fitted. Results: The prevalence estimated with the hospital data were: LBW (6%), macrosomia (0.5%) SGA (1%) and LGA (15%) and, with the data from INE: 5% 0.5% 2% 12% respectively. Kappa statistics: LBW (83%), macrosomia (79%), PEG (24%) and LGA (82%). Missing and misreported data vary with parental nationality and their situation in the labor market (OR between 1.5 y 2.2). Conclusions: Vital statistics overestimate the prevalence of SGA and underestimate the prevalence of LGA. The concordance between the sources is very good for low birthweight, macrosomia and LGA, and moderately good for SGA. Both missing and misreported birthweight and gestational age are associated with parental socioeconomic characteristics.
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- Källén, Bengt
(författare)
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Maternal use of oral decongestants and delivery outcome
- 2009
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Ingår i: Salud i Ciencia. - 1667-8990. ; 17:1, s. 41-45
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Tidskriftsartikel (refereegranskat)abstract
- The study extends a previous investigation on the use of oral decongestants during pregnancy with another 1 000 women (1 017 infants) who reported the use of such drugs in early pregnancy and 1 125 women (1 145 infants) who had such drugs prescribed later in pregnancy. The results on the beneficial delivery outcome after late use of the drugs with a reduced rate of preterm birth and low birth weight were verified and it was also shown that the rates of large-for-gestational age and heavy infants were increased. After early use of such drugs, no increased risk of congenital malformation was seen and previously published data on an association with certain malformations, thought to be due to vascular disruption, could not be supported. It is suggested that pregnancy rhinitis as an indication for the use of oral decongestants could be associated with a well functioning placenta and a good delivery outcome.
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- Palacios, Cristina, et al.
(författare)
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Asociaciones entre los niveles de vitamina d y los marcadores de glucosa en mujeres embarazadas y sus bebés en puerto rico
- 2021
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Ingår i: Nutrición Hospitalaria. - : ARAN Ediciones. - 0212-1611 .- 1699-5198. ; 38:6, s. 1224-1231
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Tidskriftsartikel (refereegranskat)abstract
- Objectives: low vitamin D during pregnancy is common and could adversely affect health outcomes. This study evaluated vitamin D status during pregnancy and early in life, and its association with glucose metabolism. Methods: maternal serum 25(OH)D, glucose, and insulin levels were measured longitudinally during pregnancy in Hispanic women with overweight/ obesity (n = 31) and their infants at birth and 4 months. Results: insulin and HOMA-IR levels were higher among women with vitamin D below adequate levels compared to those with adequate levels in pregnancy (p < 0.05). Late in pregnancy, as vitamin D increased by one unit (ng/mL), insulin decreased by 0.44 units and HOMA-IR by 0.09 units. Maternal vitamin D late in pregnancy was correlated with infant vitamin D levels at birth (r = 0.89; p < 0.01) and 4 months (r = 0.9; p = 0.04), and with glucose (r = 0.79; p = 0.03) and insulin (r = 0.83; p = 0.04) at 4 months. Conclusion: maternal vitamin D status was associated with maternal and infant glucose metabolism in this sample.
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| 6. |
- Persson, Jan
(författare)
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Fertility preservation in the treatment of early stage cervical cancer
- 2011
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Ingår i: Salud i Ciencia. - 1667-8990. ; 18:6, s. 530-534
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Forskningsöversikt (refereegranskat)abstract
- Radical trachelectomy in conjunction with pelvic lymphadenectomy is an established, safe method to preserve fertility in selected cases of early cervical cancer. The majority of publications encompass radical trachelectomy performed vaginally preceded by a laparoscopic pelvic lymphadenectomy (Dargent's operation). The invasiveness of an open abdominal trachelectomy and the complexity of a traditional laparoscopic abdominal trachelectomy may explain this dual approach. Despite more than 20 years of videolaparoscopy only a few cases of the procedure with the latter approach are available. With the introduction of robot-assisted laparoscopy, complex and rare procedures may be included in the laparoscopic arsenal and the first cases of a robot-assisted total laparoscopic trachelectomy were published in 2008. In the present paper, our further experience of a total laparoscopic trachelectomy is presented together with a stepwise description of the robotic procedure and our view of the pros and cons compared to the traditional dual laparoscopic/vaginal approach. Available publications of robot-assisted trachelectomy are reviewed.
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