SwePub
Sök i SwePub databas

  Utökad sökning

Träfflista för sökning "hsv:(MEDICIN OCH HÄLSOVETENSKAP) hsv:(Medicinska och farmaceutiska grundvetenskaper) hsv:(Fysiologi) ;pers:(Wollmer Per)"

Sökning: hsv:(MEDICIN OCH HÄLSOVETENSKAP) hsv:(Medicinska och farmaceutiska grundvetenskaper) hsv:(Fysiologi) > Wollmer Per

  • Resultat 1-10 av 26
Sortera/gruppera träfflistan
   
NumreringReferensOmslagsbildHitta
1.
  •  
2.
  •  
3.
  • Cereda, Maurizio, et al. (författare)
  • Quantitative imaging of alveolar recruitment with hyperpolarized gas MRI during mechanical ventilation
  • 2011
  • Ingår i: Journal of Applied Physiology. - : American Physiological Society. - 1522-1601 .- 8750-7587. ; 110:2, s. 499-511
  • Tidskriftsartikel (refereegranskat)abstract
    • The aim of this study was to assess the utility of He-3 MRI to noninvasively probe the effects of positive end-expiratory pressure (PEEP) maneuvers on alveolar recruitment and atelectasis buildup in mechanically ventilated animals. Sprague-Dawley rats (n = 13) were anesthetized, intubated, and ventilated in the supine position (He-4-to-O-2 ratio: 4:1; tidal volume: 10 ml/kg, 60 breaths/min, and inspiration-to-expiration ratio: 1:2). Recruitment maneuvers consisted of either a stepwise increase of PEEP to 9 cmH(2)O and back to zero end-expiratory pressure or alternating between these two PEEP levels. Diffusion MRI was performed to image He-3 apparent diffusion coefficient (ADC) maps in the middle coronal slices of lungs (n = 10). ADC was measured immediately before and after two recruitment maneuvers, which were separated from each other with a wait period (8-44 min). We detected a statistically significant decrease in mean ADC after each recruitment maneuver. The relative ADC change was -21.2 +/- 4.1 % after the first maneuver and -9.7 +/- 5.8 % after the second maneuver. A significant relative increase in mean ADC was observed over the wait period between the two recruitment maneuvers. The extent of this ADC buildup was time dependent, as it was significantly related to the duration of the wait period. The two postrecruitment ADC measurements were similar, suggesting that the lungs returned to the same state after the recruitment maneuvers were applied. No significant intrasubject differences in ADC were observed between the corresponding PEEP levels in two rats that underwent three repeat maneuvers. Airway pressure tracings were recorded in separate rats undergoing one PEEP maneuver (n = 3) and showed a significant relative difference in peak inspiratory pressure between pre- and poststates. These observations support the hypothesis of redistribution of alveolar gas due to recruitment of collapsed alveoli in presence of atelectasis, which was also supported by the decrease in peak inspiratory pressure after recruitment maneuvers.
  •  
4.
  • Dencker, Magnus, et al. (författare)
  • BMI and objectively measured body fat and body fat distribution in prepubertal children.
  • 2007
  • Ingår i: Clinical Physiology and Functional Imaging. - 1475-0961. ; 27:1, s. 12-16
  • Tidskriftsartikel (refereegranskat)abstract
    • Background Body Mass Index (BMI) is often used as a surrogate estimate of body fat in epidemiological studies. This study explores the association between BMI, body fat and body fat distribution assessed by Dual-Energy X-Ray Absorptiometry (DXA) in younger children. Methods Cross-sectional study of 246 children (138 boys and 108 girls) aged 8-11 years. DXA was used to quantify abdominal fat mass (AFM), total body fat (TBF) and also total body fat as percentage of total body mass (BF%). Body fat distribution was calculated as AFM/TBF. Results We found close correlations between BMI vs. TBF, BF% and AFM (r = 0.94, r = 0.92 and r = 0.93) for boys and (r = 0.95, r = 0.92 and r = 0.95) for girls, respectively (P < 0.05 for all r-values). However, significantly lower correlation (P < 0.001 for difference between the r-values) existed for body fat distribution (r = 0.64 for boys and 0.73 for girls). Conclusion Percentage body fat, TBF and AFM were all closely associated with BMI, suggesting that BMI serves as a good surrogate marker for obesity in population studies. However, a significantly lower correlation existed for BMI vs. body fat distribution, which may be a limitation when BMI is used to study cardiovascular risk factors in epidemiological studies.
  •  
5.
  • Dencker, Magnus, et al. (författare)
  • Body fat related to daily physical activity and insulin concentrations in non-diabetic children.
  • 2008
  • Ingår i: Clinical Physiology and Functional Imaging. - 1475-0961. ; 28, s. 211-215
  • Tidskriftsartikel (refereegranskat)abstract
    • This study explored the associations between body fat versus daily physical activity and insulin concentrations in non-diabetic young children in a cross-sectional study of 172 children (93 boys and 79 girls) aged 8-11 years. Blood samples were analysed for serum insulin and daily physical activity was measured by accelerometers. Time spent performing vigorous activity was estimated from accelerometer data by using established cut-off points. Dual-energy x-ray absorptiometry (DXA) was used to quantify abdominal fat mass (AFM) and total body fat (TBF), also calculated as percentage of body weight (BF%). Body fat distribution was calculated as AFM/TBF. Body fat distribution was independently linked to both insulin concentrations and physical activity. In contrast, TBF, AFM, and BF% were linked to physical activity only and not to insulin concentrations. In conclusion in this population of non-diabetic children, body fat distribution was independently associated with increased concentrations of insulin and deceased amount of vigorous activity per day. Also, AFM, TBF, and BF% were independently related to minutes of vigorous activity per day.
  •  
6.
  •  
7.
  • Dencker, Magnus, et al. (författare)
  • Daily physical activity and its relation to aerobic fitness in children aged 8-11 years.
  • 2006
  • Ingår i: European Journal of Applied Physiology. - : Springer Science and Business Media LLC. - 1439-6327 .- 1439-6319. ; 96:5, s. 587-592
  • Tidskriftsartikel (refereegranskat)abstract
    • A positive relationship between daily physical activity and aerobic fitness exists in adults. Studies in children have given conflicting results, possibly because of differences in methods used to assess daily physical activity and fitness. No study regarding daily physical activity and fitness in children has been published, where fitness has been assessed by direct measurement of maximum oxygen uptake and related to daily physical activity intensities by accelerometers. We examined 248 children (140 boys and 108 girls), aged 7.9-11.1 years. Maximum workload and maximal oxygen uptake (VO2PEAK) by indirect calorimetry were measured during a maximum bicycle ergometer exercise test. Exercise capacity was adjusted for body mass and (body mass)(2/3). Daily physical activity was evaluated by accelerometers, worn around the waist for 4 days. Mean accelerometer counts and time spent in vigorous physical activity were calculated. VO2PEAK was correlated with mean accelerometer counts (r=0.23 for boys and r=0.23 for girls, both P < 0.05), but somewhat better with time spent in vigorous activity (r=0.32 for boys, r=0.30 for girls, both P < 0.05). All results remained virtually the same regardless of the method used to adjust for differences in body size.
  •  
8.
  • Dencker, Magnus, et al. (författare)
  • Gender differences and determinants of aerobic fitness in children aged 8-11 years.
  • 2007
  • Ingår i: European Journal of Applied Physiology. - : Springer Science and Business Media LLC. - 1439-6327 .- 1439-6319. ; 99, s. 19-26
  • Tidskriftsartikel (refereegranskat)abstract
    • Previous studies of gender differences in maximum oxygen uptake have come to different conclusions. Limited data exists where the determinants of maximum oxygen uptake have been evaluated in a comprehensive manner. Thus, we examined 248 children (140 boys and 108 girls), aged 7.9-11.1 years. Body composition was determined by dual-energy X-ray absorptiometry, measured variables were total body fat (TBF) and lean body mass (LBM). Maximal oxygen uptake (VO2peak) was measured by indirect calorimetry during a maximal cycle exercise test. Daily physical activity was assessed by accelerometers and duration of vigorous activity per day (VPA) was calculated. Left ventricular inner diastolic diameter (LVDD) was measured by echocardiography. Lung function was evaluated with spirometric testing and whole body plethysmography. Boys had between 8 and 18% higher values than girls for VO2peak, dependent upon whether VO2peak was expressed in absolute values or scaled to body mass, LBM or if allometric scaling was used. In multiple regression analysis absolute values of aerobic fitness were independently related to LBM, maximal heart rate (Max HR), gender, LVDD, and VPA. Furthermore, when VO2peak was scaled to body mass it was independently related to In TBF, Max HR, gender, VPA, and LVDD. Lung function had no relation to VO2peak. Our study concludes that body composition is the main predictor for VO2peak, in children aged 8-11 years, whereas VPA or LVDD has only a modest impact. Existing gender differences in VO2peak cannot be explained only by differences in body composition, physical activity, or heart size.
  •  
9.
  •  
10.
  • Ek, Staffan, et al. (författare)
  • Relative Age Effect of Sport Academy Adolescents, a Physiological Evaluation
  • 2020
  • Ingår i: Sports. - Basel : MDPI. - 2075-4663. ; 8:1
  • Tidskriftsartikel (refereegranskat)abstract
    • The relationship between birth quarter distribution and physiological characteristics related to athletic skills, in adolescent sport academy students has not been fully investigated. In a cross-sectional study, we recruited 86 boys and 52 girls aged 12-14 years during their first term at a sport academy school. We measured body size, cardiac size, pulmonary function, body composition, lower body power, cardiorespiratory fitness parameters, and running endurance by standard methods and analyzed these estimates in relation to birth quarter by ANOVA. Birth quarter distribution in our cohort was compared with birth quarter distribution in the same ages in the whole of Sweden and analyzed by logistic regression. The academy had an overrepresentation of students born in the first quartile of the year compared to those born in the last quartile (odds ratio 2.3 (95% CI: 1.1-4.7)). When comparing the physiological characteristics between birth quarters, uniformity is prominent since out of 26 performed physiological and anthropometric tests only four showed statistically significant group differences. We thus believe that the selection process to the sport academy favours athletes with higher chronological age, i.e., a so-called relative age effect is present. © 2020 MDPI (Basel, Switzerland).
  •  
Skapa referenser, mejla, bekava och länka
  • Resultat 1-10 av 26
Typ av publikation
tidskriftsartikel (25)
forskningsöversikt (1)
Typ av innehåll
refereegranskat (26)
Författare/redaktör
Dencker, Magnus (9)
Thorsson, Ola (8)
Greiff, Lennart (6)
Andersson, Morgan (4)
Lindén, Christian (4)
visa fler...
Karlsson, Magnus (3)
Persson, Carl (3)
Engström, Gunnar (2)
Karlsson, Magnus K. (2)
Malinovschi, Andrei, ... (2)
Andersen, Lars (2)
Månsson, Sven (2)
Manthorpe, Rolf (2)
Eiberg, Stig (2)
Johansson, Fredrik (1)
Janson, Christer (1)
Ahren, Bo (1)
Erjefält, Jonas (1)
Groop, Leif (1)
Nylander, Tommy (1)
Jonson, Björn (1)
Torén, Kjell, 1952 (1)
Mandl, Thomas (1)
Lundin, Stefan (1)
Larsson, Bengt (1)
Engvall, Jan (1)
Hagström, Emil (1)
Sundström, Johan, Pr ... (1)
Eriksson, Karl-Fredr ... (1)
Blomberg, Anders, 19 ... (1)
Egesten, Arne (1)
Stenfors, Nikolai (1)
Lindberg, Eva (1)
Apelqvist, Jan (1)
Magnusson, Peter (1)
Olsson, Lars E (1)
Linden, Margareta (1)
Nannmark, Ulf, 1958 (1)
Korsgren, Magnus (1)
Swahn, Eva (1)
Friberg, Peter, 1956 (1)
Vanfleteren, Lowie E ... (1)
Almér, Lars-Olof (1)
Troedsson Almér, Ann ... (1)
Berg, Sören (1)
Emilsson, Össur Ingi (1)
Löfdahl, Claes-Göran (1)
Andersen, Lars B. (1)
Peterson, Tomas (1)
visa färre...
Lärosäte
Lunds universitet (24)
Uppsala universitet (2)
Göteborgs universitet (1)
Högskolan i Halmstad (1)
Malmö universitet (1)
Karolinska Institutet (1)
Språk
Engelska (26)
Forskningsämne (UKÄ/SCB)
Medicin och hälsovetenskap (26)

År

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy