| 1. |
- Hultman, Johan, et al.
(författare)
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A Resourcification Manifesto: Understanding the Social Process of Resources Becoming Resources
- 2021
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Ingår i: Research Policy. - : Elsevier BV. - 0048-7333. ; 50:9
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Tidskriftsartikel (refereegranskat)abstract
- In times of major global interconnectedness and environmental change, the pressure to identify, create, and exploit new resources is certain to intensify. Given that there are unavoidable trade-offs, conflicts, and arenas for violence involved when increasingly more material and immaterial things are turned into resources, we call for explicit research on the very process – a process that we label resourcification. The concept of resourcification shifts attention from essentialist queries about the nature of resources to a focus on the social processes through which things are turned into resources. In search of a better understanding of resources in the Anthropocene and, in particular, an understanding about the way resources emerge and are used, resourcification offers a new conceptual framework that allows for a systematic search for knowledge about the diversity of contexts, conditions, modes, and temporalities of resourcification. This Resourcification Manifesto offers a theoretical and empirical framework for a radical and disruptive approach to innovation, sustainability, and management studies and policies.
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| 2. |
- Munthe, Christian, 1962
(författare)
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Mellan genialitet och galenskap: Recension av Benjamin Labatuts roman "MANIAC"
- 2023
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Ingår i: Tidskriften Alba. - 1403-5448.
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Recension (övrigt vetenskapligt/konstnärligt)abstract
- John von Neumann var ett för de allra flesta okänt ungerskt underbarn av judisk härkomst som sedermera flydde undan nazisterna till USA, där han dog 1957. Han var ett matematiskt universalgeni som gav viktiga, för att inte säga avgörande, bidrag till fysikens, biologins, data- och samhällsvetenskapens och meteorologins (och därmed klimatvetenskapens) utveckling under 1900-talet. Vid sidan av den mer allmänt kände Alan Turing föranstaltade han det som vi idag lär känna som A.I. och teoretiserade tidigt om hur man kunde tänka på maskiner som livsformer analogt med biologiska – en idé som idag ingår både i evolutionsbiologiska verktygslådor liksom i visioner och mardrömsscenarier om en teknologisk singularitet bortom vilken generella A.I. dominerar och, i värsta fall, tränger ut människoarten. Det är denne märkliga och skrämmande person Benjamín Labatuts välskrivna roman sätter i centrum för en berättelse om gränslandet mellan genialitet och galenskap, vetenskap och teknik från förra sekelskiftet till nu, logikseminariernas tankelekar och konkret global politisk utveckling på liv och död. Romanen är pärlande klart översatt av Anna Petronella Foultier. Man behöver nog ha ett visst intresse för vetenskap, teknik och/eller global politik för att uppskatta den fullt ut, men mycket sådant förklaras under hand på ett skenbart enkelt vis, så jättestora kunskaper behövs inte.
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| 3. |
- Jagers, Peter, 1941
(författare)
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Branching Processes: A Personal Historical Perspective.
- 2020
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Ingår i: Statistical Modeling for Biological Systems: In Memory of Andrei Yakovlev. - Cham : Springer International Publishing.
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Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
- The chapter, based on an Oberwolfach talk, gives a - personally biased - sketch of the development of branching processes, from the mid 19th Century to recently, emphasizing relations to bioscience and demography, and to society and culture in general.
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| 4. |
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| 5. |
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| 6. |
- Gaskell, George, et al.
(författare)
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Europeans and biotechnology in 2002 - Eurobarometer 58.0 : A report to the EC Directorate General for Research from the project "Life Sciences in European Society"
- 2003
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- This is the fifth in a series of Eurobarometer surveys on biotechnology and the life sciences. The surveys have been conducted in 1991, 1993, 1996, 1999 and in 2002. The survey is based on a representative sample of 16 500 respondents, approximately 1 000 in each EU member state (see report for exceptions). Survey design and analysis was conducted by an international research group ‘Life Sciences in European Society’ supported by DG Research. In a year when many European countries are involved in public discussions on aspects of biotechnology, this survey stands as a contribution to the informed debate.
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| 7. |
- Juras, Anna, et al.
(författare)
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Mitochondrial genomes from Bronze Age Poland reveal genetic continuity from the Late Neolithic and additional genetic affinities with the steppe populations
- 2020
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Ingår i: American Journal of Physical Anthropology. - : Wiley. - 0002-9483 .- 1096-8644. ; 172:2, s. 176-188
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Tidskriftsartikel (refereegranskat)abstract
- Objective: In this work we aim to investigate the origins and genetic affinities of Bronze Age populations (2,400-1,100 BC) from the region of southern Poland and to trace maternal kinship patterns present in the burials of those populations by the use of complete mitochondrial genomes.Materials and methods: We performed ancient DNA analyses for Bronze Age individuals from present-day Poland associated with the Strzy(z) over dotow culture, the Mierzanowice culture, and the Trzciniec Cultural circle. To obtain complete mitochondrial genomes, we sequenced genomic libraries using Illumina platform. Additionally, hybridization capture was used to enrich some of the samples for mitochondrial DNA. AMS C-14-dating was conducted for 51 individuals to verify chronological and cultural attribution of the analyzed samples.Results: Complete ancient mitochondrial genomes were generated for 80 of the Bronze Age individuals from present-day Poland. The results of the population genetic analyses indicate close maternal genetic affinity between Mierzanowice, Trzciniec, and Corded Ware culture-associated populations. This is in contrast to the genetically more distant Strzy(z) over dotow people that displayed closer maternal genetic relation to steppe populations associated with the preceding Yamnaya culture and Catacomb culture, and with later Scythians. Potential maternal kinship relations were identified in burials of Mierzanowice and Trzciniec populations analyzed in this study.Discussion: Results revealed genetic continuity from the Late Neolithic Corded Ware groups to Bronze Age Mierzanowice and Trzciniec-associated populations, and possible additional genetic contribution from the steppe to the formation of the Strzy(z) over dotow-associated group at the end of 3rd millennium BC. Mitochondrial patterns indicated several pairs of potentially maternally related individuals mostly in Trzciniec-associated group.
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| 8. |
- Lindgren, Petter, et al.
(författare)
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A likelihood ratio-based approach for improved source attribution in microbiological forensic investigations
- 2019
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Ingår i: Forensic Science International. - : Elsevier. - 0379-0738 .- 1872-6283. ; 302
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Tidskriftsartikel (refereegranskat)abstract
- A common objective in microbial forensic investigations is to identify the origin of a recovered pathogenic bacterium by DNA sequencing. However, there is currently no consensus about how degrees of belief in such origin hypotheses should be quantified, interpreted, and communicated to wider audiences. To fill this gap, we have developed a concept based on calculating probabilistic evidential values for microbial forensic hypotheses. The likelihood-ratio method underpinning this concept is widely used in other forensic fields, such as human DNA matching, where results are readily interpretable and have been successfully communicated in juridical hearings. The concept was applied to two case scenarios of interest in microbial forensics: (1) identifying source cultures among series of very similar cultures generated by parallel serial passage of the Tier 1 pathogen Francisella tularensis, and (2) finding the production facilities of strains isolated in a real disease outbreak caused by the human pathogen Listeria monocytogenes. Evidence values for the studied hypotheses were computed based on signatures derived from whole genome sequencing data, including deep-sequenced low-frequency variants and structural variants such as duplications and deletions acquired during serial passages. In the F. tularensis case study, we were able to correctly assign fictive evidence samples to the correct culture batches of origin on the basis of structural variant data. By setting up relevant hypotheses and using data on cultivated batch sources to define the reference populations under each hypothesis, evidential values could be calculated. The results show that extremely similar strains can be separated on the basis of amplified mutational patterns identified by high-throughput sequencing. In the L. monocytogenes scenario, analyses of whole genome sequence data conclusively assigned the clinical samples to specific sources of origin, and conclusions were formulated to facilitate communication of the findings. Taken together, these findings demonstrate the potential of using bacterial whole genome sequencing data, including data on both low frequency SNP signatures and structural variants, to calculate evidence values that facilitate interpretation and communication of the results. The concept could be applied in diverse scenarios, including both epidemiological and forensic source tracking of bacterial infectious disease outbreaks.
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| 10. |
- Munthe, Christian, 1962
(författare)
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The Price of Precaution and the Ethics of Risk
- 2011
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Bok (övrigt vetenskapligt/konstnärligt)abstract
- Since a couple of decades, the notion of a precautionary principle plays a central and increasingly influential role in international as well as national policy and regulation regarding the environment and the use of technology. Urging society to take action in the face of potential risks of human activities in these areas, the recent focus on climate change has further sharpened the importance of this idea. However, the idea of a precautionary principle has also been problematised and criticised by scientists, scholars and policy activists, and been accused of almost every intellectual sin imaginable: unclarity, impracticality, arbitrariness and moral as well as political unsoundness. In that light, the very idea of precaution as an ideal for policy making rather comes out as a dead end. On the basis of these contrasting starting points, Christian Munthe undertakes an innovative, in-depth philosophical analysis of what the idea of a precautionary principle is and should be about. A novel theory of the ethics of imposing risks is developed and used as a foundation for defending the idea of precaution in environmental and technological policy making against its critics, while at the same time avoiding a number of identified flaws. The theory is shown to have far-reaching consequences for areas such as bio-, information- and nuclear technology, and global environmental policy in areas such as climate change. The author argues that, while the price we pay for precaution must not be too high, we have to be prepared to pay it in order to act ethically defensible. A number of practical suggestions for precautionary regulation and policy making are made on the basis of this, and some challenges to basic ethical theory as well as consumerist societies, the global political order and liberal democracy are identified
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