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Search: hsv:(TEKNIK OCH TEKNOLOGIER) hsv:(Maskinteknik) > Medical and Health Sciences

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1.
  • Lo Martire, Riccardo, et al. (author)
  • Construction of a web-based questionnaire for longitudinal investigation of work exposure, musculoskeletal pain and performance impairments in high-performance marine craft populations
  • 2017
  • In: BMJ Open. - : BMJ. - 2044-6055. ; 7:7
  • Journal article (peer-reviewed)abstract
    • OBJECTIVE: High-performance marine craft personnel (HPMCP) are regularly exposed to vibration and repeated shock (VRS) levels exceeding maximum limitations stated by international legislation. Whereas such exposure reportedly is detrimental to health and performance, the epidemiological data necessary to link these adverse effects causally to VRS are not available in the scientific literature, and no suitable tools for acquiring such data exist. This study therefore constructed a questionnaire for longitudinal investigations in HPMCP.METHODS: A consensus panel defined content domains, identified relevant items and outlined a questionnaire. The relevance and simplicity of the questionnaire's content were then systematically assessed by expert raters in three consecutive stages, each followed by revisions. An item-level content validity index (I-CVI) was computed as the proportion of experts rating an item as relevant and simple, and a scale-level content validity index (S-CVI/Ave) as the average I-CVI across items. The thresholds for acceptable content validity were 0.78 and 0.90, respectively. Finally, a dynamic web version of the questionnaire was constructed and pilot tested over a 1-month period during a marine exercise in a study population sample of eight subjects, while accelerometers simultaneously quantified VRS exposure.RESULTS: Content domains were defined as work exposure, musculoskeletal pain and human performance, and items were selected to reflect these constructs. Ratings from nine experts yielded S-CVI/Ave of 0.97 and 1.00 for relevance and simplicity, respectively, and the pilot test suggested that responses were sensitive to change in acceleration and that the questionnaire, following some adjustments, was feasible for its intended purpose.CONCLUSIONS: A dynamic web-based questionnaire for longitudinal survey of key variables in HPMCP was constructed. Expert ratings supported that the questionnaire content is relevant, simple and sufficiently comprehensive, and the pilot test suggested that the questionnaire is feasible for longitudinal measurements in the study population.
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2.
  • Persson, Urban, 1961- (author)
  • Realise the Potential! : Cost Effective and Energy Efficient District Heating in European Urban Areas
  • 2011
  • Licentiate thesis (other academic/artistic)abstract
    • The Member States of EU27 need to accelerate the integration of energy efficient technology solutions to reach the 20% energy efficiency target set for 2020. At current pace, projections indicate that only half of expected primary energy reductions will be reached. To meet the energy demands of growing populations and a vibrant economy, while simultaneously reducing primary energy supplies, the European continent faces a new kind of challenge never previously encountered. The identification and application of feasible, competitive, and comprehensive solutions to this problem are of highest priority if the remaining gap is to be closed in time. How is this multi-dimensional and complex dilemma to be dissolved? In this work, expanded use of district heating technology is conceived as a possible solution to substantially reduce future primary energy demands in Europe. By extended recovery and utilisation of vast volumes of currently disregarded excess heat from energy and industry sector fuel transformation processes, district heating systems and combined generation of heat and power can improve the general efficiency of the European energy balance. To investigate the possible range of this solution, this thesis introduces a set of methodologies, theoretical concepts, and model tools, by which a plausible future excess heat utilisation potential, by means of district heat deliveries to residential and service sectors, is estimated. At current conditions and compared to current levels, this potential correspond to a threefold expansion possibility for directly feasible district heating systems in European urban areas and a fourfold increase of European excess heat utilisation.
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3.
  • Powell, Nelson, et al. (author)
  • Patterns in pharyngeal airflow associated with sleep-disordered breathing
  • 2011
  • In: Sleep Medicine. - : Elsevier. - 1389-9457 .- 1878-5506. ; 12:10, s. 966-974
  • Journal article (peer-reviewed)abstract
    • Objective: To establish the feasibility of a noninvasive method to identify pharyngeal airflow characteristics in sleep-disordered breathing.Methods: Four patients with sleep-disordered breathing who underwent surgery or used positive airway pressure devices and four normal healthy controls were studied. Three-dimensional CT imaging and computational fluid dynamics modeling with standard steady-state numerical formulation were used to characterize pharyngeal airflow behavior in normals and pre-and post-treatment in patients. Dynamic flow simulations using an unsteady approach were performed in one patient.Results: The pre-treatment pharyngeal airway below the minimum cross-sectional area obstruction site showed airflow separation. This generated recirculation airflow regions and enhanced turbulence zones where vortices developed. This interaction induced large fluctuations in airflow variables and increased aerodynamic forces acting on the pharyngeal wall. At post-treatment, for the same volumetric flow rate, airflow field instabilities vanished and airflow characteristics improved. Mean maximum airflow velocity during inspiration reduced from 18.3 ± 5.7 m/s pre-treatment to 6.3 ± 4.5 m/s post-treatment (P = 0.002), leading to a reduction in maximum wall shear stress from 4.8 ± 1.7 Pa pre-treatment to 0.9 ± 1.0 Pa post-treatment (P = 0.01). The airway resistance improved from 4.3 ± 1.4 Pa/L/min at pre-treatment to 0.7 ± 0.7 Pa/L/min at post-treatment (P = 0.004). Post-treatment airflow characteristics were not different from normal controls (all P ⩾ 0.39).Conclusions: This study demonstrates that pharyngeal airflow variables may be derived from CT imaging and computational fluid dynamics modeling, resulting in high quality visualizations of airflow characteristics of axial velocity, static pressure, and wall shear stress in sleep-disordered breathing.
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4.
  • Rizzi, Maria C, et al. (author)
  • The potential of different countermeasures to prevent injuries with high risk of health loss among bicyclists in Sweden
  • 2020
  • In: Traffic Injury Prevention. - : Informa UK Limited. - 1538-9588 .- 1538-957X. ; 21:3, s. 215-221
  • Journal article (peer-reviewed)abstract
    • Objective: As bicyclists account for the largest share of serious injuries in Sweden, focus to improve safety for bicyclists is needed. While knowledge about fatal bicycle crashes is rather extensive, the number of studies that have investigated non-fatal injuries is still rather limited. The aim of this study was to estimate the potential of different countermeasures to reduce crashes resulting in injuries with high risk of health-loss among cyclists in Sweden. A further aim was to describe the residual—that is, crashes that were not considered to be addressed by the analyzed countermeasures. Methods: A sample of individuals with specific injury diagnoses was drawn from the Swedish national crash database Strada. A survey form was used to collect additional information about the crash and the health-related outcomes. The potential of countermeasures currently included in the Swedish Safety Performance Indicators, as well as of countermeasures that could be described as “existing but not fully implemented” was assessed. The overall potential of all countermeasures assessed was calculated, giving a grand total without double counting. Cases that were considered not to be addressed by any of the countermeasures included (i.e., the residual crashes) were described in more detail. Results: The current Swedish Safety Performance Indicators that relate to safe cycling addressed 22% of crashes. Improved maintenance by deicing and removal of snow from bicycle infrastructure was found to have the highest potential (8%), followed by improved crashworthiness of passenger cars (5%) and safer bicycle crossings (4%). The potential for existing but not fully implemented safety improvements was 56%. The greatest potential was found for Autonomous Emergency Braking with cyclist detection for passenger cars (12%), followed by studded winter tyres for bicycles (12%), and improved maintenance on non-bicycle infrastructure (11%). In total, taking double counting into consideration, all safety improvements could address 64% of all crashes. Among the residual crashes, the majority (69%) were single bicycle crashes of which most were related to wheel locking during braking and losing balance at low speed or stationary. Conclusions: Compared with fatal crashes that involve a majority of bicycle-car crashes, the crashes leading to health-loss are mostly single bicycle crashes. Therefore, innovation and development of additional countermeasures to improve safety for bicyclists should focus on single bicycle crashes.
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5.
  • Liu, Yuanhua, 1971, et al. (author)
  • Considering the importance of user profiles in interface design
  • 2009
  • In: User Interfaces. ; , s. 23-
  • Book chapter (other academic/artistic)abstract
    • User profile is a popular term widely employed during product design processes by industrial companies. Such a profile is normally intended to represent real users of a product. The ultimate purpose of a user profile is actually to help designers to recognize or learn about the real user by presenting them with a description of a real user’s attributes, for instance; the user’s gender, age, educational level, attitude, technical needs and skill level. The aim of this chapter is to provide information on the current knowledge and research about user profile issues, as well as to emphasize the importance of considering these issues in interface design. In this chapter, we mainly focus on how users’ difference in expertise affects their performance or activity in various interaction contexts. Considering the complex interaction situations in practice, novice and expert users’ interactions with medical user interfaces of different technical complexity will be analyzed as examples: one focuses on novice and expert users’ difference when interacting with simple medical interfaces, and the other focuses on differences when interacting with complex medical interfaces. Four issues will be analyzed and discussed: (1) how novice and expert users differ in terms of performance during the interaction; (2) how novice and expert users differ in the perspective of cognitive mental models during the interaction; (3) how novice and expert users should be defined in practice; and (4) what are the main differences between novice and expert users’ implications for interface design. Besides describing the effect of users’ expertise difference during the interface design process, we will also pinpoint some potential problems for the research on interface design, as well as some future challenges that academic researchers and industrial engineers should face in practice.
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7.
  • Elcadi, Guilherme H., 1966-, et al. (author)
  • Shoulder and forearm oxygenation and myoelectric activity in patients with work related muscle pain and healthy subjects
  • 2013
  • In: European Journal of Applied Physiology. - New York : Springer. - 1439-6319 .- 1439-6327. ; 113:5, s. 1103-1115
  • Journal article (peer-reviewed)abstract
    • We tested hypotheses of (i) reduced oxygen usage, oxygen recovery, blood flow and oxygen consumption; and (ii) increased muscle activity for patients diagnosed with work related muscle pain in comparison to healthy controls. Oxygenation was measured with near infrared spectroscopy (NIRS), and muscle activity with EMG for the extensor carpi radialis (ECR) and trapezius descendens (TD) muscles. Eighteen patients with diffuse neck-shoulder-arm pain and seventeen controls (matched in age and sex) were equipped with NIRS and EMG probes. After determining an individual’s maximum voluntary contraction (MVC) force, short term (20 sec) isometric contractions for the ECR and TD of 10%, 30%, 50% and 70% MVC generated ∆StO2% and StO2% recovery (Rslope) from NIRS, and RMS%max from EMG signals. In addition, upper arm venous (VO) and arterial (AO) occlusions generated slopes of total hemoglobin (HbTslope) and deoxyhemoglobin (HHbslope) for the resting ECR as surrogates of blood flow and oxygen consumption, respectively. Mixed Model analyses, t-tests, and Mann-Whitney test were used to assess differences between groups. There was no significant difference in MVC between groups for either muscle. Also, ∆StO2%, Rslope for either muscle, and ECR-HbTslope were not different between groups, thus our hypotheses of reduced oxygen use, recovery, and blood flow for patients were not confirmed. However, patients had a significantly lower ECR-HHbslope confirming our hypothesis of reduced consumption. Further, there was no difference in RMS%max during contractions meaning that the hypothesis of increased activity for patients was not confirmed. When taking into account the number of NIRS variables studied, differences we found between our patient group and healthy controls (i.e. in forearm oxygen consumption and shoulder oxygen saturation level) may be considered modest. Overall our findings may have been impacted by the fact that our patients and controls were similar in muscle strength, which is in contrast to previous studies.
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8.
  • Folke, Solgun, 1947-, et al. (author)
  • Views of xerostomia among health care professionals : a qualitative study
  • 2009
  • In: Journal of Clinical Nursing. - Oxford : Blackwell Publishing. - 0962-1067 .- 1365-2702. ; 18:6, s. 791-798
  • Journal article (peer-reviewed)abstract
    • AIM:To explore and describe views of xerostomia among health care professionals.BACKGROUND:Xerostomia (dry mouth) is caused by changes in quality and quantity of saliva due to poor health, certain drugs and radiation therapy. It is a common symptom, particularly among older people and has devastating consequences with regard to oral health and general well-being.METHODS:Data were obtained and categorised by interviewing 16 health care professionals. Qualitative content analysis was chosen as the method of analysis.DESIGN: Qualitative.RESULTS:The latent content was formulated into a theme: xerostomia is a well-known problem, yet there is inadequate management of patients with xerostomia. The findings identified three categories expressing the manifest content: awareness of xerostomia, indifferent attitude and insufficient support.CONCLUSIONS:Although xerostomia was recognised as commonly occurring, it was considered to be an underestimated and an ignored problem. Proper attention to conditions of xerostomia and subsequent patient management were viewed as fragmentary and inadequate. Additional qualitative studies among patients with xerostomia would be desirable to gain further understanding of the problems with xerostomia, its professional recognition and management.RELEVANCE TO CLINICAL PRACTICE:A holistic view, positive professional attitudes and enhanced knowledge of xerostomia seem essential to augment collaboration among health care professionals and to improve compassion for and support of patients with xerostomia.
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9.
  • Ghandour, Salim, et al. (author)
  • Optimization of titanium spinal cages to maximize synthetic graft content in composite implants
  • 2022
  • Conference paper (peer-reviewed)abstract
    • Spinal fusion is the gold standard for treating patients with degenerative disc disease. Titanium alloys and PEEK are the two most common materials used to manufacture cages for spinal fusion, used to maintain disc height while the vertebrae fuse. Other materials, such as morselised bone, may be added to the cage to enhance the bioactivity. A monetite-based calcium phosphate has (as a composite implant in combination with titanium) shown potentially osteoinductive properties and may be a synthetic alternative to bone graft. Maximizing the ratio of calcium phosphate to titanium could be desirable to maximize bone ingrowth and fusion. Further, the calcium phosphate can be incorporated into the cage and stored ahead of surgery. The aim of this study was to topologically optimize cervical spine implants to incorporate a bioactive but mechanically weak material such as calcium phosphate.
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10.
  • Waqas, Muhammad, 1983, et al. (author)
  • In vitro models for simulating swallowing
  • 2017
  • In: Medical radiology. - Cham : Springer International Publishing. - 9783319685717 ; , s. 549-562, s. 549-562
  • Book chapter (other academic/artistic)abstract
    • This chapter gives an overview of the in vitro models that are currently used for studying swallowing. The focus is on the construction, geometry, and performance of mechanical models. Swallowing simulations and mathematical modeling are also considered. The in vitro models that are concerned with the oral, pharyngeal, and esophageal phases of swallowing linked to bolus properties are discussed. The pharyngeal phase is given special consideration, as it is involved in both food transport to the stomach and air transport to the lungs, and therefore constitutes the most critical phase of swallowing.
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