Nanoscale Insights into Ion-Beam Cancer Therapy / edited by Andrey V. Solov’yov.

• Multiscale Physics of Ion-Beam Cancer Therapy / Eugene Surdutovich, Andrey V. Solov’yov -- Propagation of Swift Protons in Liquid Water and Generation of Secondary Electrons in Biomaterials / Pablo de Vera, Rafael Garcia-Molina, Isabel Abril -- Monte Carlo-Based Modeling of Secondary Particle Tracks Generated by Intermediate- and Low-Energy Protons in Water / Alexey Verkhovtsev, Pedro Arce, Antonio Muñoz, Francisco Blanco, Gustavo García -- Ion Collisions with Biomolecules and Biomolecular Clusters / Patrick Rousseau, Bernd A. Huber -- Dissociative Electron Attachment to Biomolecules / Ilko Bald, Roman Čurík, Janina Kopyra, Michal Tarana -- Photoprocesses with Biomolecules in the Gas Phase / Paola Bolognesi, Lorenzo Avaldi -- Irradiation-Induced Processes with Atomic Clusters and Nanoparticles / Alexey Verkhovtsev, Andrei V. Korol, Andrey V. Solov’yov -- On the Quantum Description of Irradiation Dynamics in Systems of Biological Relevance / P.M. Dinh, L. Bouëssel du Bourg, C.-Z. Gao, Bin Gu, L. Lacombe, M. McAllister, M. Smyth, G. Tribello, M. Vincendon, J. Kohanoff, P.-G. Reinhard, L. Sanche and E. Suraud -- Multiscale Modelling of Molecular Processes for Biomedical and Nanotechnology Applications with MBN Explorer / Andrey V. Solov’yov -- Thermo-Mechanical Damage of Biomolecules Under Ion-Beam Radiation / Pablo de Vera, Nigel J. Mason, Eugene Surdutovich, Andrey V. Solov’yov -- Predictive Assessment of Biological Damage Due to Ion Beams / Alexey Verkhovtsev, Eugene Surdutovich, Andrey V. Solov’yov -- New Research in Ionizing Radiation and Nanoparticles: The ARGENT Project / Marta Bolsa Ferruz, Vladimir Ivošev, Kaspar Haume, Lilian Ellis-Gibbings, Ali Traore, Vivek Thakare, Soraia Rosa, Pablo de Vera, Vu-Long Tran, Arkadiusz Mika, Daria Boscolo, Sophie Grellet, Alexey Verkhovtsev, Bernd A. Huber, Karl T. Butterworth, Kevin M. Prise, Frederick J. Currell, Nigel J. Mason, Jon Golding, Emanuele Scifoni, Gustavo García, Frédéric Boschetti, F. Lux, O. Tillement, Cédric Louis, Kurt Stokbro, Andrey V. Solov’yov and Sandrine Lacombe -- Biophysics Modeling to Optimize Ion Beam Cancer Therapy / Michaël Beuve -- Treatment Planning Systems and Hadron Therapy Practice in France / Ludovic De Marzi, Annalisa Patriarca, Alejandro Mazal, Jean-Louis Habrand. 

• This book provides a unique and comprehensive overview of state-of-the-art understanding of the molecular and nano-scale processes that play significant roles in ion-beam cancer therapy. It covers experimental design and methodology, and reviews the theoretical understanding of the processes involved. It offers the reader an opportunity to learn from a coherent approach about the physics, chemistry and biology relevant to ion-beam cancer therapy, a growing field of important medical application worldwide. The book describes phenomena occurring on different time and energy scales relevant to the radiation damage of biological targets and ion-beam cancer therapy from the molecular (nano) scale up to the macroscopic level. It illustrates how ion-beam therapy offers the possibility of excellent dose localization for treatment of malignant tumours, minimizing radiation damage in normal tissue whilst maximizing cell-killing within the tumour, offering a significant development in cancer therapy. The full potential of such therapy can only be realized by better understanding the physical, chemical and biological mechanisms, on a range of time and space scales that lead to cell death under ion irradiation. This book describes how, using a multiscale approach, experimental and theoretical expertise available can lead to greater insight at the nanoscopic and molecular level into radiation damage of biological targets induced by ion impact. The book is intended for advanced students and specialists in the areas of physics, chemistry, biology and medicine related to ion-beam therapy, radiation protection, biophysics, radiation nanophysics and chemistry, atomic and molecular physics, condensed matter physics, and the physics of interaction of charged particles with matter. One of the most important features of the book is the inclusive multiscale approach to the understanding of complex and highly interdisciplinary processes behind ion-beam cancer therapy, which stretches from the atomistic level up to the biological scale and is demonstrated to be in excellent agreement with experimental observations.

Ämnesord

Physics  (LCSH)

Cancer research  (LCSH)

Nanochemistry  (LCSH)

Nuclear physics  (LCSH)

Heavy ions  (LCSH)

Hadrons  (LCSH)

Nanoscale science  (LCSH)

Nanoscience  (LCSH)

Nanostructures  (LCSH)

Medical physics  (LCSH)

Radiation  (LCSH)

Cancer  -- Radiotherapy (LCSH)

Neoplasms  -- radiotherapy (MeSH)

Physics 

Medical and Radiation Physics 

Cancer Research 

Nanoscale Science and Technology 

Nuclear Physics, Heavy Ions, Hadrons 

Nanochemistry 

Biological and Medical Physics, Biophysics 

Publikations- och innehållstyp

615.842 (DDC)

Vmd (kssb/8 (machine generated))