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Cytokine expression...
Cytokine expression in peri-implant crevicular fluid in relation to bacterial presence
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- Renvert, Stefan (författare)
- Blekinge Tekniska Högskola,Institutionen för hälsa,Oral Health - Public Health - Quality of Life (OHAL),Oral Hälsa - Allmänhälsa - Livskvalitet (OHAL)
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- Widen, Cecilia (författare)
- University of Kristianstad
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- Persson, Gösta Rutger (författare)
- University of Kristianstad,Oral Health - Public Health - Quality of Life (OHAL),Oral Hälsa - Allmänhälsa - Livskvalitet (OHAL)
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(creator_code:org_t)
- 2015-07-17
- 2015
- Engelska.
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Ingår i: Journal of Clinical Periodontology. - : John Wiley & Sons. - 0303-6979 .- 1600-051X. ; 42:7, s. 697-702
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Aim:The aim was to assess clinical inflammatory parameters, cytokine levels and bacterial counts in samples from implant crevicular fluid in cases with untreated peri-implantitis. Material and Methods: Several bacterial species known to up-regulate pro-inflammatory cytokines have been associated with peri-implantitis. The Luminex magnet bead technology was used to study cytokines in crevicular fluid. The checkerboard DNA-DNA hybridization method was used to study bacterial counts in samples from 41 implants (41 individuals). Results: Profuse bleeding and suppuration was found in 25/41 (61.0%) of the implants. The reliability of duplicate cytokine processing was high. In the presence of profuse bleeding, higher pg/ml levels of IL-1 (p=0.02), IL-8 (p=0.04), TNF- (p=0.03) and VEGF (p=0.004) were found. Higher concentrations of IL-1 were found in the presence of suppuration, and if Escherichia coli (p=0.001) or Staphylococcus epidermidis (p=0.05) could be detected. Conclusion: Profuse bleeding and/or suppuration in untreated peri-implantitis can be associated with higher concentrations of IL-1, IL-8, TNF- and VEGF in peri-implant crevicular fluid. A higher concentration of IL-1 in peri-implant crevicular fluid was found in samples that were positive for E.coli or S.epidermidis.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Odontologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Dentistry (hsv//eng)
Nyckelord
- bacteria
- cytokines
- inflammation
- peri-implantitis
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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