Sökning: onr:"swepub:oai:DiVA.org:du-29863" > Albuminuria as a pr...
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000 | 03925naa a2200517 4500 | |
001 | oai:DiVA.org:du-29863 | |
003 | SwePub | |
008 | 190408s2019 | |||||||||||000 ||eng| | |
009 | oai:prod.swepub.kib.ki.se:141771874 | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:du-298632 URI |
024 | 7 | a https://doi.org/10.1161/JAHA.118.0105462 DOI |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1417718742 URI |
040 | a (SwePub)dud (SwePub)ki | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Mok, Yejin4 aut |
245 | 1 0 | a Albuminuria as a predictor of cardiovascular outcomes in patients with acute myocardial infarction |
264 | 1 | c 2019 |
338 | a electronic2 rdacarrier | |
520 | a Background. In patients with myocardial infarction ( MI ), reduced kidney function is recognized as an important predictor of poor prognosis, but the impact of albuminuria, a representative measure of kidney damage, has not been extensively evaluated.Methods and Results. In the SCREAM (Stockholm Creatinine Measurements) project (2006-2012), we identified 2469 patients with incident MI with dipstick proteinuria measured within a year before MI (427 patients also had urine albumin to creatinine ratio [ ACR ] measured concurrently) and obtained estimates for ACR with multiple imputation in participants with data solely on dipstick proteinuria. We quantified the association of ACR with the post- MI composite and individual outcomes of all-cause mortality, cardiovascular mortality, recurrent MI , ischemic stroke, or heart failure using Cox models and then evaluated the improvement in C statistic. During a median follow-up of 1.0 year after MI , 1607 participants (65.1%) developed the post- MI composite outcome. Higher ACR levels were independently associated with all outcomes except for ischemic stroke. Per 8-fold higher ACR (eg, 40 versus 5 mg/g), the hazard ratio of composite outcome was 1.21 (95% CI , 1.08-1.35). The addition of the ACR improved the C statistic of the post- MI composite by 0.040 (95% CI, 0.030-0.051). Largely similar results were obtained regardless of diabetic status and when ACR or dipstick was separately analyzed without imputation.Conclusions. In patients with MI , albuminuria was a potent predictor of subsequent outcomes, suggesting the importance of paying attention to the information on albuminuria, in addition to kidney function, in this high-risk population. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicin0 (SwePub)3022 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicine0 (SwePub)3022 hsv//eng |
653 | a albuminuria | |
653 | a chronic kidney disease | |
653 | a myocardial infarction | |
653 | a prognosis | |
653 | a Hälsa och välfärd | |
653 | a Health and Welfare | |
700 | 1 | a Ballew, Shoshana H4 aut |
700 | 1 | a Sang, Yingying4 aut |
700 | 1 | a Grams, Morgan Eu Karolinska Institutet4 aut |
700 | 1 | a Coresh, Josef4 aut |
700 | 1 | a Evans, Marie4 aut |
700 | 1 | a Barany, Peteru Karolinska Institutet4 aut |
700 | 1 | a Ärnlöv, Johan,d 1970-u Karolinska Institutet,Högskolan Dalarna,Medicinsk vetenskap,Karolinska institutet4 aut0 (Swepub:du)jan |
700 | 1 | a Carrero, Juan-Jesusu Karolinska Institutet4 aut |
700 | 1 | a Matsushita, Kunihiro4 aut |
710 | 2 | a Karolinska Institutetb Medicinsk vetenskap4 org |
773 | 0 | t Journal of the American Heart Associationg 8:8q 8:8x 2047-9980 |
856 | 4 | u https://doi.org/10.1161/JAHA.118.010546y Fulltext |
856 | 4 | u https://du.diva-portal.org/smash/get/diva2:1302930/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:du-29863 |
856 | 4 8 | u https://doi.org/10.1161/JAHA.118.010546 |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:141771874 |
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