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Sökning: onr:"swepub:oai:DiVA.org:du-39397" > Genetically Predict...
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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 03687naa a2200481 4500 | |
| 001 | oai:DiVA.org:du-39397 | |
| 003 | SwePub | |
| 008 | 220207s2022 | |||||||||||000 ||eng| | |
| 009 | oai:prod.swepub.kib.ki.se:148869201 | |
| 009 | oai:DiVA.org:uu-469068 | |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:du-393972 URI |
| 024 | 7 | a https://doi.org/10.3390/nu140305092 DOI |
| 024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1488692012 URI |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4690682 URI |
| 040 | a (SwePub)dud (SwePub)kid (SwePub)uu | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Ahmad, Shafqatu Uppsala universitet,Molekylär epidemiologi,Science for Life Laboratory, SciLifeLab,Harvard Med Sch, Brigham & Womens Hosp, Div Prevent Med, Boston, MA 02115 USA.4 aut0 (Swepub:uu)shaah996 |
| 245 | 1 0 | a Genetically Predicted Circulating Copper and Risk of Chronic Kidney Disease :b A Mendelian Randomization Study |
| 264 | c 2022-01-25 | |
| 264 | 1 | b MDPI,c 2022 |
| 338 | a electronic2 rdacarrier | |
| 520 | a Elevated circulating copper levels have been associated with chronic kidney disease (CKD), kidney damage, and decline in kidney function. Using a two sample Mendelian randomization approach where copper-associated genetic variants were used as instrumental variables, genetically predicted higher circulating copper levels were associated with higher CKD prevalence (odds ratio 1.17; 95% confidence interval 1.04, 1.32; p-value = 0.009). There was suggestive evidence that genetically predicted higher copper was associated with a lower estimated glomerular filtration rate and a more rapid kidney damage decline. In conclusion, we observed that elevated circulating copper levels may be a causal risk factor for CKD. © 2022 by the authors. Licensee MDPI, Basel, Switzerland. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Urologi och njurmedicin0 (SwePub)302142 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Urology and Nephrology0 (SwePub)302142 hsv//eng |
| 653 | a Circulating nutrients | |
| 653 | a Estimated glomerular filtration rate | |
| 653 | a Kidney related disease | |
| 653 | a Mendelian randomization | |
| 700 | 1 | a Ärnlöv, Johan,d 1970-u Högskolan Dalarna,Medicinsk vetenskap,Karolinska Institutet, Stockholm,Karolinska Inst, Div Family Med & Primary Care, Dept Neurobiol Care Sci & Soc NVS, S-14152 Stockholm, Sweden.;Dalarna Univ, Sch Hlth & Social Studies, S-79131 Falun, Sweden.4 aut0 (Swepub:du)jan |
| 700 | 1 | a Larsson, Susanna C.u Uppsala universitet,Karolinska Institutet,Ortopedi,Medicinsk epidemiologi,Karolinska Inst, Inst Environm Med, Unit Cardiovasc & Nutr Epidemiol, S-17177 Stockholm, Sweden.;Uppsala Univ, Dept Surg Sci, Unit Med Epidemiol, S-75185 Uppsala, Sweden.4 aut0 (Swepub:uu)susla720 |
| 710 | 2 | a Uppsala universitetb Molekylär epidemiologi4 org |
| 773 | 0 | t Nutrientsd : MDPIg 14:3q 14:3x 2072-6643 |
| 856 | 4 | u https://doi.org/10.3390/nu14030509y Fulltext |
| 856 | 4 | u https://du.diva-portal.org/smash/get/diva2:1635699/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print |
| 856 | 4 | u https://www.mdpi.com/2072-6643/14/3/509/pdf |
| 856 | 4 | u https://uu.diva-portal.org/smash/get/diva2:1642301/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:du-39397 |
| 856 | 4 8 | u https://doi.org/10.3390/nu14030509 |
| 856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:148869201 |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-469068 |
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