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Underlying reasons ...
Underlying reasons for sex difference in survival following out-of-hospital cardiac arrest: a mediation analysis
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- Miedel, Charlotte (författare)
- Department of Clinical Science and Education, Center for Resuscitation Science, Södersjukhuset, Karolinska Institutet , Sjukhusbacken 10, 118 83, Stockholm , Sweden
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- Jonsson, Martin (författare)
- Karolinska Institutet,Department of Clinical Science and Education, Center for Resuscitation Science, Södersjukhuset, Karolinska Institutet , Sjukhusbacken 10, 118 83, Stockholm , Sweden
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- Dragas, Mariana (författare)
- Department of Clinical Science and Education, Center for Resuscitation Science, Södersjukhuset, Karolinska Institutet , Sjukhusbacken 10, 118 83, Stockholm , Sweden
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- Djärv, Therese (författare)
- Karolinska Institutet,Department of Clinical Science and Education, Center for Resuscitation Science, Södersjukhuset, Karolinska Institutet , Sjukhusbacken 10, 118 83, Stockholm , Sweden;Department of Medicine, Karolinska Institutet , Solna , Sweden
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- Nordberg, Per (författare)
- Karolinska Institutet,Department of Clinical Science and Education, Center for Resuscitation Science, Södersjukhuset, Karolinska Institutet , Sjukhusbacken 10, 118 83, Stockholm , Sweden
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- Rawshani, Araz, 1986 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine,Department of Molecular and Clinical Medicine, Institute of Medicine, University of Gothenburg, Sahlgrenska Academy , Gothenburg , Sweden
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- Claesson, Andreas (författare)
- Karolinska Institutet,Department of Clinical Science and Education, Center for Resuscitation Science, Södersjukhuset, Karolinska Institutet , Sjukhusbacken 10, 118 83, Stockholm , Sweden;Department of Molecular and Clinical Medicine, Institute of Medicine, University of Gothenburg, Sahlgrenska Academy , Gothenburg , Sweden
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- Forsberg, Sune (författare)
- Karolinska Institutet,Department of Clinical Science and Education, Center for Resuscitation Science, Södersjukhuset, Karolinska Institutet , Sjukhusbacken 10, 118 83, Stockholm , Sweden
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- Nord, Anette (författare)
- Department of Clinical Science and Education, Center for Resuscitation Science, Södersjukhuset, Karolinska Institutet , Sjukhusbacken 10, 118 83, Stockholm , Sweden
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- Herlitz, Johan, 1949- (författare)
- Högskolan i Borås,Akademin för vård, arbetsliv och välfärd,Department of Clinical Science and Education, Center for Resuscitation Science, Södersjukhuset, Karolinska Institutet , Sjukhusbacken 10, 118 83, Stockholm , Sweden,PreHospen
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- Riva, Gabriel (författare)
- Karolinska Institutet,Department of Clinical Science and Education, Center for Resuscitation Science, Södersjukhuset, Karolinska Institutet , Sjukhusbacken 10, 118 83, Stockholm , Sweden
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(creator_code:org_t)
- 2024
- 2024
- Engelska.
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Ingår i: Europace. - 1099-5129 .- 1532-2092. ; 26:5
- Relaterad länk:
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https://doi.org/10.1...
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https://hb.diva-port... (primary) (Raw object)
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https://urn.kb.se/re...
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https://doi.org/10.1...
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http://kipublication...
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http://kipublication...
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https://gup.ub.gu.se...
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Abstract
Ämnesord
Stäng
- AimsPrevious studies have indicated a poorer survival among women following out-of-hospital cardiac arrest (OHCA), but the mechanisms explaining this difference remain largely uncertain.This study aimed to assess the survival after OHCA among women and men and explore the role of potential mediators, such as resuscitation characteristics, prior comorbidity, and socioeconomic factors.Methods and resultsThis was a population-based cohort study including emergency medical service-treated OHCA reported to the Swedish Registry for Cardiopulmonary Resuscitation in 2010–2020, linked to nationwide Swedish healthcare registries. The relative risks (RR) of 30-day survival were compared among women and men, and a mediation analysis was performed to investigate the importance of potential mediators. Total of 43 226 OHCAs were included, of which 14 249 (33.0%) were women. Women were older and had a lower proportion of shockable initial rhythm. The crude 30-day survival among women was 6.2% compared to 10.7% for men [RR 0.58, 95% confidence interval (CI) = 0.54–0.62]. Stepwise adjustment for shockable initial rhythm attenuated the association to RR 0.85 (95% CI = 0.79–0.91). Further adjustments for age and resuscitation factors attenuated the survival difference to null (RR 0.98; 95% CI = 0.92–1.05). Mediation analysis showed that shockable initial rhythm explained ∼50% of the negative association of female sex on survival. Older age and lower disposable income were the second and third most important variables, respectively.ConclusionWomen have a lower crude 30-day survival following OHCA compared to men. The poor prognosis is largely explained by a lower proportion of shockable initial rhythm, older age at presentation, and lower income.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
Nyckelord
- OHCA
- SCD
- Sex
- Gender
- Ventricular arrhythmia
- Women’s health
- Människan i vården
- The Human Perspective in Care
- OHCA
- SCD
- Sex
- Gender
- Ventricular arrhythmia
- Women's health
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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Europace
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Till lärosätets databas
- Av författaren/redakt...
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Miedel, Charlott ...
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Jonsson, Martin
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Dragas, Mariana
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Djärv, Therese
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Nordberg, Per
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Rawshani, Araz, ...
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Claesson, Andrea ...
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Forsberg, Sune
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Nord, Anette
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Herlitz, Johan, ...
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Riva, Gabriel
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- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Kardiologi
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Hälsovetenskap
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och Folkhälsovetensk ...
- Artiklar i publikationen
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Europace
- Av lärosätet
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Högskolan i Borås
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Karolinska Institutet
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Göteborgs universitet