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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00005033naa a2200625 4500
001oai:DiVA.org:hkr-21304
003SwePub
008201020s2021 | |||||||||||000 ||eng|
009oai:prod.swepub.kib.ki.se:233426158
009oai:prod.swepub.kib.ki.se:148612900
0247 a urn:nbn:se:hkr:diva-213042 urn
0247 a https://doi.org/10.1002/mdc3.131022 DOI
0247 a http://kipublications.ki.se/Default.aspx?queryparsed=id:2334261582 URI
0247 a http://kipublications.ki.se/Default.aspx?queryparsed=id:1486129002 URI
040 a (SwePub)hkrd (SwePub)ki
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Höglund, Arjau Karolinska institutet & Karolinska universitetssjukhuset4 aut
2451 0a Associations between fluctuations in daytime sleepiness and motor and non-motor symptoms in Parkinson's disease
264 1c 2021
338 a print2 rdacarrier
506 a gratis
520 a Abstract Background Non-motor fluctuations (NMF) are a major concern in Parkinson's disease (PD), and they have been categorised into neuropsychiatric, autonomic and sensory fluctuations. However, this categorisation does not include sleep and sleep-related features, and the association between daytime sleepiness and other motor and/or non-motor fluctuations in PD remains to be elucidated. Objective To investigate the relationship between daytime sleepiness and other non-motor and motor fluctuations in people with PD. Methods A three-day home diary recording daytime sleepiness, mood, anxiety, and motor symptoms was used along with the Karolinska Sleepiness Scale (KSS) and six days of accelerometer (Parkinson's KinetiGraph?; PKG?) registration to detect motor fluctuations among people with a DaTSCAN verified clinical PD diagnosis (32 men; mean PD duration, 8.2?years). Participants were categorised as motor fluctuators or non-fluctuators according to the UPDRS part IV and/or the presence of motor and non-motor fluctuations. Results Fifty-two people with PD participated. Daytime sleepiness correlated significantly with motor symptoms, mood and anxiety among those classified as motor fluctuators (n = 28). Motor fluctuators showed stronger correlations between the individual mean level of all diary variables (daytime sleepiness, anxiety, mood and motor symptoms) when compared to the non-fluctuators (n = 24). Stronger positive within-individual correlations were found among fluctuators in comparison to non-fluctuators. In general, PKG data did not correlate with diary data. Conclusion Episodes of daytime sleepiness, as reported by home diaries, were associated with other self-reported non-motor and motor fluctuations, but were not supported by PKG data.
650 7a MEDICAL AND HEALTH SCIENCESx Health Sciences0 (SwePub)3032 hsv//eng
650 7a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskaper0 (SwePub)3032 hsv//swe
653 a Daytime sleepiness
653 a Parkinson's disease
653 a motor fluctuations and non-motor fluctuations
653 a home diary
653 a PKG
7001 a Hagell, Peteru Högskolan Kristianstad,Forskningsmiljön PRO-CARE, Patient Reported Outcomes - Clinical Assessment Research and Education,Avdelningen för sjuksköterskeutbildningarna och integrerad hälsovetenskap4 aut0 (Swepub:hkr)hape
7001 a Broman, Jan-Eriku Uppsala universitet4 aut
7001 a Pålhagen, Svenu Karolinska institutet & Karolinska universitetssjukhuset4 aut
7001 a Sorjonen, Kimmou Karolinska institutet4 aut
7001 a Fredrikson, Stenu Karolinska institutet & karolinska universitetssjukhuset4 aut
7001 a Svenningsson, Peru Karolinska institutet & Karolinska universitetssjukhuset4 aut
7001 a Fredrikson, Su Karolinska Institutet4 aut
7001 a Hagell, P4 aut
7001 a Broman, JE4 aut
7001 a Höglund, Au Karolinska Institutet4 aut
7001 a Svenningsson, Pu Karolinska Institutet4 aut
7001 a Pålhagen, Su Karolinska Institutet4 aut
7001 a Sorjonen, Ku Karolinska Institutet4 aut
7001 a Palhagen, Su Karolinska Institutet4 aut
7001 a Hoglund, Au Karolinska Institutet4 aut
7102 a Karolinska institutet & Karolinska universitetssjukhusetb Forskningsmiljön PRO-CARE, Patient Reported Outcomes - Clinical Assessment Research and Education4 org
7730 t Movement Disorders Clinical Practiceg 8:1, s. 44-50q 8:1<44-50x 2330-1619
8564 u https://movementdisorders.onlinelibrary.wiley.com/doi/pdfdirect/10.1002/mdc3.13102
8564 u https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/mdc3.13102
8564 8u http://urn.kb.se/resolve?urn=urn:nbn:se:hkr:diva-21304x lärosäteslänky Till lärosätets (hkr) databas
8564 8u https://doi.org/10.1002/mdc3.13102
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:233426158
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:148612900

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