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Affinity ligands fo...
Affinity ligands for industrial protein purification
- Artikel/kapitelEngelska2005
Förlag, utgivningsår, omfång ...
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Bentham Science Publishers Ltd.2005
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printrdacarrier
Nummerbeteckningar
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LIBRIS-ID:oai:DiVA.org:kth-14755
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https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-14755URI
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https://doi.org/10.2174/0929866053765662DOI
Kompletterande språkuppgifter
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Språk:engelska
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Sammanfattning på:engelska
Ingår i deldatabas
Klassifikation
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Ämneskategori:ref swepub-contenttype
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Ämneskategori:for swepub-publicationtype
Anmärkningar
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QC 20100525
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Significant efforts are put into the design of large-scale purification processes of proteins due to great demands regarding cost efficiency and safety. In order to design an effective purification scheme the unit operations need to be reduced to a minimum. In this review we are discussing proteinaceous ligands as well as small synthetic mimics for use in affinity chromatography for large-scale applications. Different advantages as well as drawbacks of the two approaches are outlined.
Ämnesord och genrebeteckningar
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Affinity chromatography
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cleaning-in-place (CIP)
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deamidation
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protein A
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protein G
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protein engineering
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stabilization
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escherichia-coli
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synthetic ligand
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deamidation
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chromatography
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peptides
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residues
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stability
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design
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immobilization
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mutagenesis
Biuppslag (personer, institutioner, konferenser, titlar ...)
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Gulich, S.
(författare)
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Hober, SophiaKTH,Proteomik(Swepub:kth)u11qqzc1
(författare)
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KTHProteomik
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:Protein peptide letters: Bentham Science Publishers Ltd.12:4, s. 305-3100929-86651875-5305
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