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Carbohydrate conjug...
Carbohydrate conjugation through microwave-assisted functionalization of single-walled carbon nanotubes using perfluorophenyl azides
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- Kong, Na (författare)
- KTH,Organisk kemi,KTH—Royal Institute of Technology, Department of Chemistry, Teknikringen 30, S-10044 Stockholm, Sweden
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- Shimpi, Manishkumar R. (författare)
- KTH,Organisk kemi,KTH—Royal Institute of Technology, Department of Chemistry, Teknikringen 30, S-10044 Stockholm, Sweden
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- Park, Jae Hyeung (författare)
- Department of Chemistry, University of Massachusetts Lowell, 1 University Ave., Lowell, MA 01854, United States
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- Ramström, Olof (författare)
- KTH,Organisk kemi,KTH—Royal Institute of Technology, Department of Chemistry, Teknikringen 30, S-10044 Stockholm, Sweden
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- Yan, Mingdi (författare)
- KTH,Organisk kemi,KTH—Royal Institute of Technology, Department of Chemistry, Teknikringen 30, S-10044 Stockholm, Sweden; Department of Chemistry, University of Massachusetts Lowell, 1 University Ave., Lowell, MA 01854, United States
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(creator_code:org_t)
- Elsevier BV, 2015
- 2015
- Engelska.
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Ingår i: Carbohydrate Research. - : Elsevier BV. - 0008-6215 .- 1873-426X. ; 405, s. 33-38
- Relaterad länk:
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https://europepmc.or...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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Abstract
Ämnesord
Stäng
- Carbohydrate-functionalized single-walled carbon nanotubes (SWNTs) were synthesized using microwave-assisted reaction of perfluorophenyl azide with the nanotubes. The results showed that microwave radiation provides a rapid and effective means to covalently attach carbohydrates to SWNTs, producing carbohydrate-SWNT conjugates for biorecognition. The carbohydrate-functionalized SWNTs were furthermore shown to interact specifically with cognate carbohydrate-specific proteins (lectins), resulting in predicted recognition patterns. The carbohydrate-presenting SWNTs constitute a new platform for sensitive protein-or cell recognition, which pave the way for glycoconjugated carbon nanomaterials in biorecognition applications.
Ämnesord
- NATURVETENSKAP -- Kemi (hsv//swe)
- NATURAL SCIENCES -- Chemical Sciences (hsv//eng)
- NATURVETENSKAP -- Kemi -- Fysikalisk kemi (hsv//swe)
- NATURAL SCIENCES -- Chemical Sciences -- Physical Chemistry (hsv//eng)
Nyckelord
- Single-walled carbon nanotubes
- Microwave
- Perfluorophenyl azide
- Covalent functionalization
- Carbohydrate
- Lectin
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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