Improved properties of gold nanorods coated with thin multilayer of small organic molecules by fast and facile method for surface enhanced Raman scattering

• We introduce a thin multilayer-shell-coated gold nanorods (GNRs) that we have been able to achieve by way of coating them with two thin layers of small organic molecules in a new, efficient, effective, time-saving, and easy-to-control multilayer coating method. Compared to the thick shell, due to the small size of the coating molecules, this new type of GNR, by simply mixed with the sample solution, has shown that it can act as a highly effective and improved surface enhanced Raman scattering (SERS) enhancement agent without the need of any sample connecting or doping. This enhancement is found not only related to the off-resonance surface enhancement, but also to the increased signal-to-noise ratio brought by the low level of fluorescence emission. It showed excellent stability in strong acids, bases and some organic solvents as examined by comparing the longitudinal surface plasmon resonance peak values. A living body experiment on a tumor-bearing nude mouse injected with the Raman reporter dye loaded onto our new GNRs showed strong surface enhanced Raman scattering signal in the tumor, suggesting its high potential use in many related optical applications.

Ämnesord

TEKNIK OCH TEKNOLOGIER  -- Elektroteknik och elektronik (hsv//swe)

ENGINEERING AND TECHNOLOGY  -- Electrical Engineering, Electronic Engineering, Information Engineering (hsv//eng)

Nyckelord

Fluorescence quench

Gold nanorods

Multilayer

Surface enhanced Raman scattering

Surface plasmon resonance

Tumor

Coatings

Fluorescence

Gold

Gold coatings

Molecules

Multilayers

Nanoribbons

Nanorods

Plasmons

Raman scattering

Resonance

Signal to noise ratio

Tumors

Fluorescence emission

Gold nanorod

Gold nanorods (GNRs)

Longitudinal surface plasmon resonances

Multi-layer-coating

Optical applications

Small organic molecules

Surface enhanced Raman Scattering (SERS)

Surface scattering

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