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Staphylococcal surf...
Staphylococcal surface display and its applications
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Ståhl, Stefan (författare)
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Robert, A. (författare)
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Gunneriusson, E. (författare)
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- Wernérus, Henrik (författare)
- KTH,Bioteknologi
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Cano, F. (författare)
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Liljeqvist, S. (författare)
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Hansson, M. (författare)
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Nguyen, T. N. (författare)
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- Samuelson, Patrik (författare)
- KTH,Bioteknologi
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(creator_code:org_t)
- Elsevier BV, 2000
- 2000
- Engelska.
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Ingår i: International Journal of Medical Microbiology. - : Elsevier BV. - 1438-4221 .- 1618-0607. ; 290:7, s. 571-577
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Novel surface proteins can be introduced onto the bacterial cell surface by recombinant means. Here, we describe the development of such display systems for two food-grade bacteria, Staphylococcus carnosus and Staphylococcus xylosus, and present how such engineered bacteria can be used in different applications. A study will be described in which such staphylococci were employed as vaccine delivery vehicles to elicit protective antibody responses to respiratory syncytial virus (RSV). The use of surface-engineered staphylococci as novel microbial biocatalysts, as a new type of whole-cell diagnostic devices or for adsorption of metal ions with potential environmental or biosensor applications, will also be discussed.
Nyckelord
- Staphylococcus carnosus
- Staphylococcus xylosus
- vaccine delivery
- diagnostic tools
- environmental applications
- toxin-b subunit
- cell-surface
- combinatorial libraries
- recombinant proteins
- antibody-responses
- vaccine delivery
- binding
- carnosus
- xylosus
- aureus
Publikations- och innehållstyp
- ref (ämneskategori)
- for (ämneskategori)
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