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Sökning: onr:"swepub:oai:DiVA.org:kth-210609" > Preliminary study o...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00005043naa a2200601 4500
001oai:DiVA.org:kth-210609
003SwePub
008170703s2017 | |||||||||||000 ||eng|
009oai:DiVA.org:uu-396782
009oai:DiVA.org:liu-137824
009oai:prod.swepub.kib.ki.se:136175590
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-2106092 URI
0247 a https://doi.org/10.1088/1748-0221/12/05/C050092 DOI
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3967822 URI
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-1378242 URI
0247 a http://kipublications.ki.se/Default.aspx?queryparsed=id:1361755902 URI
040 a (SwePub)kthd (SwePub)uud (SwePub)liud (SwePub)ki
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Bennati, Paolou KTH,Medicinsk teknik,KTH, Royal Institute of Technology, Stockholm, Sweden4 aut0 (Swepub:kth)u1ua4ia4
2451 0a Preliminary study of a new gamma imager for on-line proton range monitoring during proton radiotherapy
264 1b Institute of Physics Publishing (IOPP),c 2017
338 a print2 rdacarrier
500 a QC 20170703
520 a We designed and tested new concept imaging devices, based on a thin scintillating crystal, aimed at the online monitoring of the range of protons in tissue during proton radiotherapy. The proposed crystal can guarantee better spatial resolution and lower sensitivity with respect to a thicker one, at the cost of a coarser energy resolution. Two different samples of thin crystals were coupled to a position sensitive photo multiplier tube read out by 64 independent channels electronics. The detector was equipped with a knife-edge Lead collimator that defined a reasonable field of view of about 10 cm in the target. Geant4 Monte Carlo simulations were used to optimize the design of the experimental setup and assess the accuracy of the results. Experimental measurements were carried out at the Skandion Clinic, the recently opened proton beam facility in Uppsala, Sweden. PMMA and water phantoms studies were performed with a first prototype based on a round 6.0 mm thick Cry019 crystal and with a second detector based on a thinner 5 × 5 cm2, 2.0 mm thick LFS crystal. Phantoms were irradiated with mono-energetic proton beams whose energy was in the range between 110 and 160 MeV. According with the simulations and the experimental data, the detector based on LFS crystal seems able to identify the peak of prompt-gamma radiation and its results are in fair agreement with the expected shift of the proton range as a function of energy. The count rate remains one of the most critical limitations of our system, which was able to cope with only about 20% of the clinical dose rate. Nevertheless, we are confident that our study might provide the basis for developing a new full-functional system.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Radiologi och bildbehandling0 (SwePub)302082 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Radiology, Nuclear Medicine and Medical Imaging0 (SwePub)302082 hsv//eng
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng
653 a Gamma detectors
653 a Gamma detectors (scintillators
653 a CZT
653 a HPG
653 a HgI etc)
653 a Instrumentation for hadron therapy
7001 a Dasu, Alexandruu The Skandion Clinic, Uppsala, Sweden4 aut0 (Swepub:liu)aleda92
7001 a Colarieti-Tosti, Massimilianou KTH,Medicinsk bildteknik,KTH, Royal Institute of Technology, Stockholm, Sweden4 aut0 (Swepub:kth)u1byfik5
7001 a Lönn, Gustafu KTH,Medicinsk teknik,KTH, Royal Institute of Technology, Stockholm, Sweden4 aut0 (Swepub:kth)u1hi06ki
7001 a Larsson, Davidu Karolinska Institutet,KTH,Medicinsk bildteknik,KTH, Royal Institute of Technology, Stockholm, Sweden4 aut0 (Swepub:kth)u1klpk46
7001 a Fabbri, A.u INFN, National Institute for Nuclear Physics, Rome, Italy4 aut
7001 a Galasso, M.u INFN, National Institute for Nuclear Physics, Rome, Italy4 aut
7001 a Cinti, M. N.u Sapienza University, Rome, Italy4 aut
7001 a Pellegrini, R.u Sapienza University, Rome, Italy4 aut
7001 a Pani, R.u Sapienza University, Rome, Italy4 aut
7102 a KTHb Medicinsk teknik4 org
7730 t Journal of Instrumentationd : Institute of Physics Publishing (IOPP)g 12:5q 12:5x 1748-0221
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-210609
8564 8u https://doi.org/10.1088/1748-0221/12/05/C05009
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-396782
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-137824
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:136175590

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