Effects of training with flow restriction on the exercise pressor reflex

QC 20180914
We hypothesized that 5 weeks of endurance training with blood flow restriction (R-training), providing relative ischemia and stimulation of the muscle chemoreflex, would decrease the exercise pressor reflex (EPR) when compared to training with the same workload in a free-flow condition (NR-training). 10 subjects performed one-leg knee-extension training four times a week during a 5-week period. Both legs were trained with identical workload, with one leg being trained during flow-restriction induced by lower body positive pressure. The EPR was assessed by measuring the increase in heart rate (HR) and mean arterial pressure (MAP) during an isometric knee extension of 35% of max torque for 90 s, this was done before (C), and after training in each leg (R and NR, respectively). At the end of isometric contraction, the increase in mean AP (MAP) in the NR-trained leg and in the control condition were 41 +/- 4 and 38 +/- 4 mmHg, respectively, whereas the increase in the R-trained leg was 30 +/- 4 mmHg (p < 0.05 R vs C and NR), corresponding to a decrease of about 25%. A similar patter was observed with respect to responses in HR, where the increase was 28 +/- 3 and 28 +/- 3 bpm in the NR and C, and 22 +/- 4 in the R condition (p < 0.05 R vs C and NR). Peripheral metabolic changes induced by relative ischemia are important in modifying the EPR in response to exercise training.

Ingår i:European Journal of Applied Physiology: Springer118:9, s. 1903-19091439-63191439-6327

Av författaren/redakt...: Sundblad, Patrik; Kölegård, Roger; Rullman, Eric; Gustafsson, Thom ...

Om ämnet

MEDICIN OCH HÄLSOVETENSKAP: MEDICIN OCH HÄLS ...; och Medicinska och f ...; och Fysiologi

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