Solubility of paracetamol in binary and ternary mixtures of water + acetone + toluene

• The solubility of paracetamol (4-hydroxyacetanilide) in binary mixtures of acetone + water and acetone + toluene and in ternary mixtures of water + acetone + toluene is reported. The temperature range is -5 to +30°C. In acetone + water the solubility increases to a maximum at approximately 25 mass % water before decreasing to a much lower value in pure water as compared to pure acetone. In acetone + toluene the solubility decreases monotonically with increasing toluene concentration. The water content has a strong influence also in ternary mixtures. Activity coefficients in the saturated solutions are estimated.

Subject headings

TEKNIK OCH TEKNOLOGIER  -- Kemiteknik (hsv//swe)

ENGINEERING AND TECHNOLOGY  -- Chemical Engineering (hsv//eng)

Publication and Content Type

ref (subject category)

art (subject category)