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Pressure and flow p...
Pressure and flow properties of dual-lumen cannulae for extracorporeal membrane oxygenation
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- Broman, L. M. (författare)
- Karolinska Institutet
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Westlund, C. J. (författare)
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Gilbers, M. (författare)
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Perry da Câmara, L. (författare)
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- Prahl Wittberg, Lisa, Docent, 1978- (författare)
- KTH,Linné Flow Center, FLOW,BioMEx,Mekanik
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Taccone, F. S. (författare)
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Malfertheiner, M. V. (författare)
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Di Nardo, M. (författare)
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Swol, J. (författare)
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Vercaemst, L. (författare)
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Barrett, N. A. (författare)
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Pappalardo, F. (författare)
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Belohlavek, J. (författare)
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Belliato, M. (författare)
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Lorusso, R. (författare)
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(creator_code:org_t)
- 2020-06-05
- 2020
- Engelska.
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Ingår i: Perfusion. - : SAGE Publications Ltd. - 0267-6591 .- 1477-111X.
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- Introduction: In the last decade, dual-lumen cannulae have been increasingly applied in patients undergoing extracorporeal life support. Well-performing vascular access is crucial for efficient extracorporeal membrane oxygenation support; thus, guidance for proper cannulae size is required. Pressure–flow charts provided by manufacturers are often based on tests performed using water, rarely blood. However, blood is a shear-thinning and viscoelastic fluid characterized by different flow properties than water. Methods: We performed a study evaluating pressure–flow curves during standardized conditions using human whole blood in two commonly available dual-lumen cannulae used in neonates, pediatric, and adult patients. Results were merged and compared with the manufacturer’s corresponding curves obtained from the public domain. Results: The results showed that using blood as compared with water predominantly influenced drainage flow. A 10-80% higher pressure-drop was needed to obtain same drainage flow (hematocrit of 26%) compared with manufacturer’s water charts in 13-31 Fr bi-caval dual-lumen cannulae. The same net difference was found in cavo-atrial cannulae (16-32 Fr), where a lower drainage pressure was required (Hct of 26%) compared with the manufacturer’s test using blood with an Hct of 33%. Return pressure–flow data were similar, independent whether pumping blood or water, to the data reported by manufacturers. Conclusion: Non-standardized testing of pressure–flow properties of extracorporeal membrane oxygenation dual-lumen cannulae prevents an adequate prediction of pressure–flow results when these cannulae are used in patients. Properties of dual-lumen cannulae may vary between sizes within same cannula family, in particular concerning the drainage flow.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Nyckelord
- blood
- cannula
- dual lumen
- extracorporeal membrane oxygenation
- pressure–flow
- venous
- water
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas
- Av författaren/redakt...
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Broman, L. M.
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Westlund, C. J.
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Gilbers, M.
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Perry da Câmara, ...
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Prahl Wittberg, ...
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Taccone, F. S.
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visa fler...
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Malfertheiner, M ...
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Di Nardo, M.
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Swol, J.
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Vercaemst, L.
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Barrett, N. A.
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Pappalardo, F.
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Belohlavek, J.
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Belliato, M.
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Lorusso, R.
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visa färre...
- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Kardiologi
- Artiklar i publikationen
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Perfusion
- Av lärosätet
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Kungliga Tekniska Högskolan
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Karolinska Institutet