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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 03950naa a2200697 4500 | |
| 001 | oai:DiVA.org:kth-287138 | |
| 003 | SwePub | |
| 008 | 201203s2020 | |||||||||||000 ||eng| | |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-2871382 URI |
| 024 | 7 | a https://doi.org/10.1002/mabi.2020001032 DOI |
| 040 | a (SwePub)kth | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Eslami, M.4 aut |
| 245 | 1 0 | a A One Step Procedure toward Conductive Suspensions of Liposome-Polyaniline Complexes |
| 264 | c 2020-06-15 | |
| 264 | 1 | b Wiley,c 2020 |
| 338 | a print2 rdacarrier | |
| 500 | a QC 20201203 | |
| 520 | a Interaction of conjugated polymers with liposomes is an attractive approach that benefits from both systems’ characteristics such as electroactivity and enhanced interaction with cells. Conjugated polymer-liposome complexes have been investigated for bioimaging, drug delivery, and photothermal therapy. Their fabrication has largely been achieved by multistep procedures that require first the synthesis and processing of the conjugated polymer. Here, a new one step fabrication approach is reported based on in situ polymerization of a conjugated monomer precursor around liposomes. Polyaniline (PANI) doped with phytic acid is synthesized via oxidative polymerization in the presence of 1,2-dioleoyl-sn-glycero-3-phosphatidylcholine (DOPC) vesicles to produce a conductive aqueous suspension of Liposome-PANI complexes. PANI interacts with liposomes without disrupting the bilayer as shown using differential scanning calorimetry and fluorescence quenching studies of the hydrophobic Nile red probe. The electronic conductivity of the Liposome-PANI complexes, which stems from the doped PANI accessible on the liposome surface, is confirmed using conductive atomic force microscopy and electrochemical impedance spectroscopy. Further, short-term in vitro cell studies show that the complexes colocalize with the cell membrane without reducing cell proliferation. This study presents a novel fabrication route to conductive suspensions of conjugated polymer-liposome complexes suitable for potential applications at the biointerface. | |
| 650 | 7 | a NATURVETENSKAPx Kemix Polymerkemi0 (SwePub)104062 hsv//swe |
| 650 | 7 | a NATURAL SCIENCESx Chemical Sciencesx Polymer Chemistry0 (SwePub)104062 hsv//eng |
| 653 | a complex | |
| 653 | a conductive suspensions | |
| 653 | a conjugated polymers | |
| 653 | a liposomes | |
| 653 | a Cell proliferation | |
| 653 | a Cells | |
| 653 | a Cytology | |
| 653 | a Differential scanning calorimetry | |
| 653 | a Electrochemical impedance spectroscopy | |
| 653 | a Polymerization | |
| 653 | a Quenching | |
| 653 | a Suspensions (fluids) | |
| 653 | a Synthesis (chemical) | |
| 653 | a Conductive atomic force microscopy | |
| 653 | a Electronic conductivity | |
| 653 | a In-situ polymerization | |
| 653 | a Multi-step procedures | |
| 653 | a Oxidative polymerization | |
| 653 | a Photothermal therapy | |
| 653 | a Polyaniline complexes | |
| 653 | a Synthesis and processing | |
| 653 | a Drug delivery | |
| 700 | 1 | a Zeglio, Ericau KTH,Mikro- och nanosystemteknik4 aut0 (Swepub:kth)u140hbga |
| 700 | 1 | a Alosaimi, G.4 aut |
| 700 | 1 | a Yan, Y.4 aut |
| 700 | 1 | a Ruprai, H.4 aut |
| 700 | 1 | a Macmillan, A.4 aut |
| 700 | 1 | a Seidel, J.4 aut |
| 700 | 1 | a Lauto, A.4 aut |
| 700 | 1 | a Joukhdar, H.4 aut |
| 700 | 1 | a Rnjak-Kovacina, J.4 aut |
| 700 | 1 | a Mawad, D.4 aut |
| 710 | 2 | a KTHb Mikro- och nanosystemteknik4 org |
| 773 | 0 | t Macromolecular Bioscienced : Wileyg 20:11q 20:11x 1616-5187x 1616-5195 |
| 856 | 4 | u https://rss.onlinelibrary.wiley.com/doi/am-pdf/10.1002/mabi.202000103 |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-287138 |
| 856 | 4 8 | u https://doi.org/10.1002/mabi.202000103 |
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