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Evaluation of in vi...
Evaluation of in vitro corrosion resistance and in vivo osseointegration properties of a FeMnSiCa alloy as potential degradable implant biomaterial
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- Trinca, Lucia Carmen (författare)
- Ion Ionescu de la Brad Univ Agr Sci & Vet Med, Exact Sci Dept, Fac Hort, Str Aleea M Sadoveanu 3, Iasi 700490, Romania.
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- Burtan, Liviu (författare)
- Ion Ionescu de la Brad Univ Agr Sci & Vet Med, Clin Dept, Fac Vet Med, Str Aleea M Sadoveanu 8, Iasi 700489, Romania.
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- Mareci, Daniel (författare)
- Tech Univ Gheorghe Asachi Iasi, Dept Chem Engn, Fac Chem Engn & Environm Protect, Iasi 700050, Romania.
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- Fernandez-Perez, Bibiana M. (författare)
- KTH,Skolan för kemi, bioteknologi och hälsa (CBH),Univ La Laguna, Dept Chem, Avda Astrofis Francisco Sanchez S-N, E-38200 Tenerife, Canary Islands, Spain.
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- Stoleriu, Iulian (författare)
- Alexandru Ioan Cuza Univ, Fac Math, Bd Carol I 11, Iasi 700506, Romania.
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- Stanciu, Teodor (författare)
- Gheorghe Asachi Tech Univ Iasi, Fac Mat Sci & Engn, Str Prof Dr Doc Dimitrie Mangeron 67, Iasi 70005, Romania.
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- Stanciu, Sergiu (författare)
- Gheorghe Asachi Tech Univ Iasi, Fac Mat Sci & Engn, Str Prof Dr Doc Dimitrie Mangeron 67, Iasi 70005, Romania.
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- Solcan, Carmen (författare)
- Ion Ionescu de la Brad Univ Agr Sci & Vet Med, Preclin Dept, Fac Vet Med, Str Aleea M Sadoveanu 8, Iasi 700489, Romania.
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- Izquierdo, Javier (författare)
- Univ La Laguna, Dept Chem, Avda Astrofis Francisco Sanchez S-N, E-38200 Tenerife, Canary Islands, Spain.;Univ La Laguna, Inst Mat Sci & Nanotechnol, POB 456, E-38200 Tenerife, Canary Islands, Spain.
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- Souto, Ricardo M. (författare)
- Univ La Laguna, Dept Chem, Avda Astrofis Francisco Sanchez S-N, E-38200 Tenerife, Canary Islands, Spain.;Univ La Laguna, Inst Mat Sci & Nanotechnol, POB 456, E-38200 Tenerife, Canary Islands, Spain.
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Ion Ionescu de la Brad Univ Agr Sci & Vet Med, Exact Sci Dept, Fac Hort, Str Aleea M Sadoveanu 3, Iasi 700490, Romania Ion Ionescu de la Brad Univ Agr Sci & Vet Med, Clin Dept, Fac Vet Med, Str Aleea M Sadoveanu 8, Iasi 700489, Romania. (creator_code:org_t)
- Elsevier BV, 2021
- 2021
- Engelska.
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Ingår i: Materials science & engineering. C, biomimetic materials, sensors and systems. - : Elsevier BV. - 0928-4931 .- 1873-0191. ; 118
- Relaterad länk:
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https://riull.ull.es...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- In vitro electrochemical characterization and in vivo implantation in an animal model were employed to evaluate the degradation behaviour and the biological activity of FeMnSi and FeMnSiCa alloys obtained using UltraCast (Ar atmosphere) melting. Electrochemical characterization was based on open circuit potential measurement, electrochemical impedance spectroscopy and potentiodynamic polarization techniques while the alloys were immersed in Ringer's solution at 37 degrees C for 7 days. Higher corrosion rates were measured for the Cacontaining material, resulting from inefficient passivation of the metal surface by oxy-hydroxide products. In vivo osseointegration was investigated on a tibia implant model in rabbits by referring to a standard control (AISI 316 L) stainless steel using standard biochemical, histological and radiological methods of investigation. Changes in the biochemical parameters were related to the main stages of the bone defect repair, whereas implantation of the alloys in rabbit's tibia provided the necessary mechanical support to the injured bone area and facilitated the growth of the newly connective tissue, as well as osteoid formation and mineralization, as revealed by either histological sections or computed tomography reconstructed images and validated by the bone morphometric indices. The present study highlighted that the FeMnSiCa alloy promotes better osteoinduction and osseconduction processes when compared to the base FeMnSi alloy or with AISI 316 L, and in vivo degradation rates correlate well with corrosion resistance measurements in Ringer's solution.
Nyckelord
- Biodegradable implant materials
- Surface characterization
- Corrosion resistance
- FeMnSiCa alloy
- FeMnSi alloy
- Osseointegration
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Trinca, Lucia Ca ...
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Burtan, Liviu
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Mareci, Daniel
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Fernandez-Perez, ...
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Stoleriu, Iulian
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Stanciu, Teodor
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Stanciu, Sergiu
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Solcan, Carmen
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Izquierdo, Javie ...
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Souto, Ricardo M ...
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