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Tem grid preparatio...
Tem grid preparation with minimal user interaction
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- Hauser, Janosch (författare)
- KTH,Mikro- och nanosystemteknik
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Kylberg, G. (författare)
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- Stemme, Göran, 1958- (författare)
- KTH,Mikro- och nanosystemteknik
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visa fler...
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Sintorn, I. -M (författare)
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- Roxhed, Niclas (författare)
- KTH,Mikro- och nanosystemteknik
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visa färre...
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(creator_code:org_t)
- Chemical and Biological Microsystems Society, 2020
- 2020
- Engelska.
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Ingår i: MicroTAS 2020 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences. - : Chemical and Biological Microsystems Society. ; , s. 1081-1082
- Relaterad länk:
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https://urn.kb.se/re...
Abstract
Ämnesord
Stäng
- Transmission electron microscopy (TEM) allows to directly visualize and characterize small biological particles, such as viruses, making it an indispensable tool for development of vaccines and pharmaceuticals. However, the manual TEM grid preparation protocol strongly depends on the skill of the operator and affects the preparation consistency. Here, we present a capillary-driven microfluidic device for negative stain TEM (nsTEM) grid preparation with minimal user interaction. The presented device could make TEM grid preparations more consistent and provide non-specialists access to biological TEM investigations.
Ämnesord
- NATURVETENSKAP -- Kemi -- Fysikalisk kemi (hsv//swe)
- NATURAL SCIENCES -- Chemical Sciences -- Physical Chemistry (hsv//eng)
Nyckelord
- Capillary-driven
- Electron microscopy
- Sample preparation
- TEM
- Virus
- Viruses
- Biological particles
- Indispensable tools
- Micro-fluidic devices
- TEM grids
- User interaction
- High resolution transmission electron microscopy
Publikations- och innehållstyp
- ref (ämneskategori)
- kon (ämneskategori)