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An automated microf...
An automated microfluidic diagnostics pipeline for infectious disease detection in low resource settings
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- Urrutia Iturritza, Miren (författare)
- KTH,Science for Life Laboratory, SciLifeLab,Nanobioteknologi
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- Gaudenzi, Giulia (författare)
- KTH,Nanobioteknologi,Science for Life Laboratory, SciLifeLab
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- Akhtar, Ahmad Saleem (författare)
- KTH,Nanobioteknologi,Science for Life Laboratory, SciLifeLab
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visa fler...
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- Pinto, Ines Fernandes (författare)
- KTH,Nanobioteknologi,Science for Life Laboratory, SciLifeLab
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- Lapins, Noa (författare)
- KTH,Nanobioteknologi
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- Russom, Aman, Prof. 1976- (författare)
- KTH,Science for Life Laboratory, SciLifeLab,Nanobioteknologi
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- Jönsson, Håkan, PhD, 1979- (författare)
- KTH,Science for Life Laboratory, SciLifeLab,Proteinvetenskap
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visa färre...
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(creator_code:org_t)
- Chemical and Biological Microsystems Society, 2020
- 2020
- Engelska.
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Ingår i: MicroTAS 2020 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences. - : Chemical and Biological Microsystems Society. ; , s. 1197-1198
- Relaterad länk:
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https://urn.kb.se/re...
Abstract
Ämnesord
Stäng
- While diagnostics are critical for accurate and timely diagnosis, gold-standard diagnostic tests are commonly high- performance laboratory-based tests that require multi-step protocols for complex sample processing and highly trained personnel, both scarce in low-resource settings. Here, we address the need for an easy-to-use, rapid and reliable diagnostic testing pipeline by presenting a solution combining open-source modular automation and automation compatible microfluidics, easily adaptable to a pipeline for infectious diseases diagnosis. We demonstrate an automation compatible microfluidics pipeline for Neisseria meningitidis diagnosis by on-chip nucleic acids isolation and isothermal amplification, as well as pathogen detection on a paper-based microarray.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Infektionsmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Infectious Medicine (hsv//eng)
Nyckelord
- Automation
- Diagnostics
- Global health
- Infectious diseases
- Microfluidics
- Modular robotics
- Diseases
- Nucleic acids
- Pipelines
- Diagnostic testing
- Diagnostic tests
- Infectious disease
- Isothermal amplifications
- Low-resource settings
- Multi step protocols
- Neisseria meningitidis
- Pathogen detection
- Diagnosis
Publikations- och innehållstyp
- ref (ämneskategori)
- kon (ämneskategori)