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Sökning: onr:"swepub:oai:DiVA.org:kth-305700" > Multivalent glycoco...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00006592naa a2200709 4500
001oai:DiVA.org:kth-305700
003SwePub
008211206s2013 | |||||||||||000 ||eng|
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-3057002 URI
0247 a https://doi.org/10.1039/c2cs35408j2 DOI
040 a (SwePub)kth
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a for2 swepub-publicationtype
1001 a Bernardi, Annau Univ Milan, Dipartimento Chim Organ & Ind, I-20133 Milan, Italy.;Univ Milan, Ctr Eccellenza CISI, I-20133 Milan, Italy.4 aut
2451 0a Multivalent glycoconjugates as anti-pathogenic agents
264 c 2013
264 1b Royal Society of Chemistry (RSC),c 2013
338 a print2 rdacarrier
500 a QC 20211206
520 a Multivalency plays a major role in biological processes and particularly in the relationship between pathogenic microorganisms and their host that involves protein-glycan recognition. These interactions occur during the first steps of infection, for specific recognition between host and bacteria, but also at different stages of the immune response. The search for high-affinity ligands for studying such interactions involves the combination of carbohydrate head groups with different scaffolds and linkers generating multivalent glycocompounds with controlled spatial and topology parameters. By interfering with pathogen adhesion, such glycocompounds including glycopolymers, glycoclusters, glycodendrimers and glyconanoparticles have the potential to improve or replace antibiotic treatments that are now subverted by resistance. Multivalent glycoconjugates have also been used for stimulating the innate and adaptive immune systems, for example with carbohydrate-based vaccines. Bacteria present on their surfaces natural multivalent glycoconjugates such as lipopolysaccharides and S-layers that can also be exploited or targeted in anti-infectious strategies.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Mikrobiologi inom det medicinska området0 (SwePub)301092 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Microbiology in the medical area0 (SwePub)301092 hsv//eng
7001 a Jimenez-Barbero, Jesusu CSIC, Ctr Invest Biol, Madrid 28040, Spain.4 aut
7001 a Casnati, Alessandrou Univ Parma, Dipartimento Chim, I-43100 Parma, Italy.4 aut
7001 a De Castro, Cristinau Univ Naples Federico II, Dept Chem Sci, I-80126 Naples, Italy.4 aut
7001 a Darbre, Tamisu Univ Bern, Dept Chem & Biochem, CH-3012 Bern, Switzerland.4 aut
7001 a Fieschi, Francku Inst Biol Struct, F-38027 Grenoble 1, France.4 aut
7001 a Finne, Jukkau Univ Helsinki, Dept Biosci, FI-00014 Helsinki, Finland.4 aut
7001 a Funken, Horstu Univ Dusseldorf, Forschungszentrum Julich, Inst Mol Enzyme Technol, D-42425 Julich, Germany.4 aut
7001 a Jaeger, Karl-Erichu Univ Dusseldorf, Forschungszentrum Julich, Inst Mol Enzyme Technol, D-42425 Julich, Germany.4 aut
7001 a Lahmann, Martinau Bangor Univ, Sch Chem, Bangor LL57 2UW, Gwynedd, Wales.4 aut0 (Swepub:kth)u190mcjj
7001 a Lindhorst, Thisbe K.u Univ Kiel, Otto Diels Inst Organ Chem, D-24098 Kiel, Germany.4 aut
7001 a Marradi, Marcou CIC BiomaGUNE, Lab GlycoNanotechnol, San Sebastian 20009, Spain.;CIBER BBN, San Sebastian 20009, Spain.4 aut
7001 a Messner, Paulu Univ Nat Resources & Life Sci, NanoGlycobiol Unit, Dept NanoBiotechnol, A-1190 Vienna, Austria.4 aut
7001 a Molinaro, Antoniou Univ Naples Federico II, Dept Chem Sci, I-80126 Naples, Italy.4 aut
7001 a Murphy, Paul V.u Natl Univ Ireland, Sch Chem, Galway, Ireland.4 aut
7001 a Nativi, Cristinau Univ Florence, Dipartimento Chim, I-50019 Sesto Fiorentino, Italy.4 aut
7001 a Oscarson, Stefanu Univ Coll Dublin, UCD Sch Chem & Chem Biol, Ctr Synth & Chem Biol, Dublin 4, Ireland.4 aut
7001 a Penades, Soledadu CIC BiomaGUNE, Lab GlycoNanotechnol, San Sebastian 20009, Spain.;CIBER BBN, San Sebastian 20009, Spain.4 aut
7001 a Peri, Francescou Univ Milano Bicocca, I-20126 Milan, Italy.4 aut
7001 a Pieters, Roland J.u Univ Utrecht, Utrecht Inst Pharmaceut Sci, Dept Med Chem & Chem Biol, NL-3508 TB Utrecht, Netherlands.4 aut
7001 a Renaudet, Olivieru Univ Grenoble 1, UMR CNRS 5250, Dept Chim Mol, F-38041 Grenoble, France.;Univ Grenoble 1, ICMG FR 2607, F-38041 Grenoble, France.4 aut
7001 a Reymond, Jean-Louisu Univ Bern, Dept Chem & Biochem, CH-3012 Bern, Switzerland.4 aut
7001 a Richichi, Barbarau Univ Florence, Dipartimento Chim, I-50019 Sesto Fiorentino, Italy.4 aut
7001 a Rojo, Javieru Univ Seville, CSIC, Inst Invest Quim, Glycosyst Lab, Seville 41092, Spain.4 aut
7001 a Sansone, Francescou Univ Parma, Dipartimento Chim, I-43100 Parma, Italy.4 aut
7001 a Schaeffer, Christinau Univ Nat Resources & Life Sci, NanoGlycobiol Unit, Dept NanoBiotechnol, A-1190 Vienna, Austria.4 aut
7001 a Turnbull, W. Bruceu Univ Leeds, Sch Chem, Leeds LS2 9JT, W Yorkshire, England.;Univ Leeds, Astbury Ctr Struct Mol Biol, Leeds LS2 9JT, W Yorkshire, England.4 aut
7001 a Velasco-Torrijos, Trinidadu Natl Univ Ireland, Dept Chem, Maynooth, Kildare, Ireland.4 aut
7001 a Vidal, Sebastienu Univ Lyon 1, CNRS, Inst Chim & Biochim Mol & Supramol UMR 5246, F-69622 Villeurbanne, France.;Univ Namur FUNDP, Dept Chim, Chim Bioorgan Lab, B-5000 Namur, Belgium.4 aut
7001 a Vincent, Stephane4 aut
7001 a Wennekes, Tomu Wageningen Univ, Organ Chem Lab, NL-6703 HB Wageningen, Netherlands.4 aut
7001 a Zuilhof, Hanu Wageningen Univ, Organ Chem Lab, NL-6703 HB Wageningen, Netherlands.;King Abdulaziz Univ, Dept Chem & Mat Engn, Jeddah 21413, Saudi Arabia.4 aut
7001 a Imberty, Anneu Univ Grenoble, Ctr Rech Macromol Vegetales CERMAV CNRS, F-38041 Grenoble, France.4 aut
7102 a Univ Milan, Dipartimento Chim Organ & Ind, I-20133 Milan, Italy.;Univ Milan, Ctr Eccellenza CISI, I-20133 Milan, Italy.b CSIC, Ctr Invest Biol, Madrid 28040, Spain.4 org
7730 t Chemical Society Reviewsd : Royal Society of Chemistry (RSC)g 42:11, s. 4709-4727q 42:11<4709-4727x 0306-0012x 1460-4744
8564 u https://doi.org/10.1039/c2cs35408jy Fulltext
8564 u https://pubs.rsc.org/en/content/articlepdf/2013/cs/c2cs35408j
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-305700
8564 8u https://doi.org/10.1039/c2cs35408j

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