Sökning: onr:"swepub:oai:DiVA.org:kth-309550" >
Accessing Perfluoro...
Accessing Perfluoroaryl Sulfonimidamides and Sulfoximines via Photogenerated Perfluoroaryl Nitrenes : Synthesis and Application as a Chiral Auxiliary
-
- Proietti, Giampiero (författare)
- KTH,Organisk kemi
-
- Kuzmin, Julius (författare)
- KTH,Organisk kemi
-
- Temerdashev, Azamat Z. (författare)
- Kuban State Univ, Dept Analyt Chem, Krasnodar 350040, Russia.
-
visa fler...
-
- Dinér, Peter (författare)
- KTH,Organisk kemi
-
visa färre...
-
(creator_code:org_t)
- 2021-11-12
- 2021
- Engelska.
-
Ingår i: Journal of Organic Chemistry. - : American Chemical Society (ACS). - 0022-3263 .- 1520-6904. ; 86:23, s. 17119-17128
- Relaterad länk:
-
https://doi.org/10.1...
-
visa fler...
-
https://pubs.acs.org...
-
https://urn.kb.se/re...
-
https://doi.org/10.1...
-
visa färre...
Abstract
Ämnesord
Stäng
- Sulfonimidamides (SIAs) and sulfoximines (SOIs) have attracted attention due to their potential in agriculture and in medicinal chemistry as bioisosteres of biologically active compounds, and new synthetic methods are needed to access and explore these compounds. Herein, we present a light-promoted generation of perfluorinated aromatic nitrenes, from perfluorinated azides, that subsequently are allowed to react with sulfinamides and sulfoxides, generating achiral and chiral SIAs and SOIs. One of the enantiopure SIAs was evaluated as a novel chiral auxiliary in Grignard additions to the imines yielding the product in up to 96:4 diastereomeric ratio.
Ämnesord
- NATURVETENSKAP -- Kemi -- Organisk kemi (hsv//swe)
- NATURAL SCIENCES -- Chemical Sciences -- Organic Chemistry (hsv//eng)
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas