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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 23212naa a2201825 4500 | |
| 001 | oai:DiVA.org:kth-330088 | |
| 003 | SwePub | |
| 008 | 230626s2023 | |||||||||||000 ||eng| | |
| 009 | oai:lup.lub.lu.se:13c6b992-22aa-4bcc-b353-dbd6f2f72642 | |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-3300882 URI |
| 024 | 7 | a https://doi.org/10.1038/s41587-022-01520-x2 DOI |
| 024 | 7 | a https://lup.lub.lu.se/record/13c6b992-22aa-4bcc-b353-dbd6f2f726422 URI |
| 040 | a (SwePub)kthd (SwePub)lu | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Allesøe, Rosa Lundbyeu Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Department of Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark; Copenhagen Research Centre for Mental Health, Mental Health Centre Copenhagen, Copenhagen University Hospital, Copenhagen, Denmark4 aut |
| 245 | 1 0 | a Discovery of drug–omics associations in type 2 diabetes with generative deep-learning models |
| 264 | c 2023-01-02 | |
| 264 | 1 | b Springer Nature,c 2023 |
| 338 | a print2 rdacarrier | |
| 500 | a Correction in DOI 10.1038/s41587-023-01805-9QC 20230626 | |
| 520 | a The application of multiple omics technologies in biomedical cohorts has the potential to reveal patient-level disease characteristics and individualized response to treatment. However, the scale and heterogeneous nature of multi-modal data makes integration and inference a non-trivial task. We developed a deep-learning-based framework, multi-omics variational autoencoders (MOVE), to integrate such data and applied it to a cohort of 789 people with newly diagnosed type 2 diabetes with deep multi-omics phenotyping from the DIRECT consortium. Using in silico perturbations, we identified drug–omics associations across the multi-modal datasets for the 20 most prevalent drugs given to people with type 2 diabetes with substantially higher sensitivity than univariate statistical tests. From these, we among others, identified novel associations between metformin and the gut microbiota as well as opposite molecular responses for the two statins, simvastatin and atorvastatin. We used the associations to quantify drug–drug similarities, assess the degree of polypharmacy and conclude that drug effects are distributed across the multi-omics modalities. | |
| 650 | 7 | a NATURVETENSKAPx Biologix Bioinformatik och systembiologi0 (SwePub)106102 hsv//swe |
| 650 | 7 | a NATURAL SCIENCESx Biological Sciencesx Bioinformatics and Systems Biology0 (SwePub)106102 hsv//eng |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Endokrinologi och diabetes0 (SwePub)302052 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Endocrinology and Diabetes0 (SwePub)302052 hsv//eng |
| 653 | a Deep learning | |
| 653 | a Learning systems | |
| 653 | a Patient treatment | |
| 653 | a 'omics' | |
| 653 | a Auto encoders | |
| 653 | a In-silico | |
| 653 | a Learning models | |
| 653 | a Multi-modal data | |
| 653 | a Multi-modal dataset | |
| 653 | a Non-trivial tasks | |
| 653 | a Omics technologies | |
| 653 | a Phenotyping | |
| 653 | a Type-2 diabetes | |
| 653 | a Modal analysis | |
| 700 | 1 | a Lundgaard, Agnete Troenu Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Department of Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark4 aut |
| 700 | 1 | a Hernández Medina, Ricardou Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark4 aut |
| 700 | 1 | a Aguayo-Orozco, Alejandrou Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Department of Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark4 aut |
| 700 | 1 | a Johansen, Joachimu Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Department of Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark4 aut |
| 700 | 1 | a Nissen, Jakob Nybou Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark4 aut |
| 700 | 1 | a Brorsson, Carolineu Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Department of Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark4 aut |
| 700 | 1 | a Mazzoni, Gianlucau Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Department of Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark4 aut |
| 700 | 1 | a Niu, Liliu Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark4 aut |
| 700 | 1 | a Biel, Jorge Hernansanzu Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Department of Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark4 aut |
| 700 | 1 | a Brasas, Valentasu Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark4 aut |
| 700 | 1 | a Webel, Henryu Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark4 aut |
| 700 | 1 | a Benros, Michael Eriksenu Copenhagen Research Centre for Mental Health, Mental Health Centre Copenhagen, Copenhagen University Hospital, Copenhagen, Denmark; Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark4 aut |
| 700 | 1 | a Pedersen, Anders Gormu Department of Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark4 aut |
| 700 | 1 | a Chmura, Piotr Jaroslawu Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Department of Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark4 aut |
| 700 | 1 | a Jacobsen, Ulrik Plesneru Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Department of Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark4 aut |
| 700 | 1 | a Mari, Andreau C.N.R. Institute of Neuroscience, Padova, Italy4 aut |
| 700 | 1 | a Koivula, Robertu Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK4 aut |
| 700 | 1 | a Mahajan, Anubhau Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK4 aut |
| 700 | 1 | a Vinuela, Anau Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland; Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle, UK4 aut |
| 700 | 1 | a Tajes, Juan Fernandezu Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK4 aut |
| 700 | 1 | a Sharma, Sapnau Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Bavaria, Germany, Bavaria; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Bavaria, Germany, Bavaria; Chair of Food Chemistry and Molecular and Sensory Science, Technical University of Munich, Freising, Germany4 aut |
| 700 | 1 | a Haid, Marku Metabolomics and Proteomics Core, Helmholtz Zentrum Muenchen, German Research Center for Environmental Health, Neuherberg, Germany4 aut |
| 700 | 1 | a Hong, Mun-Gwanu KTH,Science for Life Laboratory, SciLifeLab,Proteinvetenskap4 aut0 (Swepub:kth)u19gmsru |
| 700 | 1 | a Musholt, Petra B.u Research and Development Global Development, Translational Medicine and Clinical Pharmacology, Sanofi-Aventis Deutschland, Frankfurt, Germany4 aut |
| 700 | 1 | a De Masi, Federicou Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Department of Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark4 aut |
| 700 | 1 | a Vogt, Josefu Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark4 aut |
| 700 | 1 | a Pedersen, Helle Kroghu Department of Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark4 aut |
| 700 | 1 | a Gudmundsdottir, Valborgu Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Department of Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark4 aut |
| 700 | 1 | a Jones, Angusu University of Exeter Medical School, Exeter, UK4 aut |
| 700 | 1 | a Kennedy, Gwenu The Immunoassay Biomarker Core Laboratory, School of Medicine, University of Dundee, Dundee, UK4 aut |
| 700 | 1 | a Bell, Jimmyu Research Centre for Optimal Health, Department of Life Sciences, University of Westminster, London, UK4 aut |
| 700 | 1 | a Thomas, E. Louiseu Research Centre for Optimal Health, Department of Life Sciences, University of Westminster, London, UK4 aut |
| 700 | 1 | a Frost, Garyu Section for Nutrition Research, Faculty of Medicine, Imperial College London, London, UK4 aut |
| 700 | 1 | a Thomsen, Henriku Department of Radiology, Copenhagen University Hospital Herlev-Gentofte, Herlev, Denmark4 aut |
| 700 | 1 | a Hansen, Elizavetau Department of Radiology, Copenhagen University Hospital Herlev-Gentofte, Herlev, Denmark4 aut |
| 700 | 1 | a Hansen, Tue Haldoru Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark4 aut |
| 700 | 1 | a Vestergaard, Henriku Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark4 aut |
| 700 | 1 | a Ridderstråle, M.u Lund University,Lunds universitet,Genomik, diabetes och endokrinologi,Forskargrupper vid Lunds universitet,Genomics, Diabetes and Endocrinology,Lund University Research Groups4 aut0 (Swepub:lu)endo-mri |
| 700 | 1 | a Blom, Marieke T.u Department of General Practice, Amsterdam Public Health Research Institute, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands4 aut |
| 700 | 1 | a ‘t Hart, Leen M.u Department of Epidemiology and Data Science, Amsterdam Public Health Research Institute, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands; Department of Biomedical Data Science, Section Molecular Epidemiology, Leiden University Medical Center, Leiden, the Netherlands; Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, the Netherlands4 aut |
| 700 | 1 | a Pattou, Francoisu Inserm, Univ Lille, CHU Lille, Lille Pasteur Institute, EGID, Lille, France4 aut |
| 700 | 1 | a Raverdy, Violetau Inserm, Univ Lille, CHU Lille, Lille Pasteur Institute, EGID, Lille, France4 aut |
| 700 | 1 | a Brage, Sorenu MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK4 aut |
| 700 | 1 | a Kokkola, Tarjau Department of Medicine, University of Eastern Finland, Kuopio, Finland4 aut |
| 700 | 1 | a Heggie, Alisonu Institute of Cellular Medicine, Newcastle University, Newcastle, UK4 aut |
| 700 | 1 | a McEvoy, Donnau Diabetes Research Network, Royal Victoria Infirmary, Newcastle, UK4 aut |
| 700 | 1 | a Klintenberg, M.u Lund University,Lunds universitet,Genomik, diabetes och endokrinologi,Forskargrupper vid Lunds universitet,Genomics, Diabetes and Endocrinology,Lund University Research Groups4 aut0 (Swepub:lu)med-mk1 |
| 700 | 1 | a Kaye, Janeu Centre for Health, Law and Emerging Technologies (HeLEX), Faculty of Law, University of Oxford, Oxford, UK4 aut |
| 700 | 1 | a Hattersley, Andrewu University of Exeter Medical School, Exeter, UK4 aut |
| 700 | 1 | a McDonald, Timothyu University of Exeter Medical School, Exeter, UK4 aut |
| 700 | 1 | a Ridderstråle, Martinu Lund University Diabetes Centre, Department of Clinical Sciences, Lund University, Malmö, Sweden4 aut |
| 700 | 1 | a Walker, Marku Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle, UK4 aut |
| 700 | 1 | a Forgie, Ianu Division of Population Health & Genomics, School of Medicine, University of Dundee, Dundee, UK4 aut |
| 700 | 1 | a Giordano, G.N.u Lund University,Lunds universitet,Genetisk och molekylär epidemiologi,Forskargrupper vid Lunds universitet,Genetic and Molecular Epidemiology,Lund University Research Groups4 aut0 (Swepub:lu)med-geg |
| 700 | 1 | a Pavo, Imreu Eli Lilly Regional Operations, Vienna, Austria4 aut |
| 700 | 1 | a Ruetten, Hartmutu Research and Development Global Development, Translational Medicine and Clinical Pharmacology, Sanofi-Aventis Deutschland, Frankfurt, Germany4 aut |
| 700 | 1 | a Pedersen, Olufu Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark4 aut |
| 700 | 1 | a Hansen, Torbenu Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark4 aut |
| 700 | 1 | a Dermitzakis, Emmanouilu Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland4 aut |
| 700 | 1 | a Franks, P.W.u Lund University,Lunds universitet,Genetisk och molekylär epidemiologi,Forskargrupper vid Lunds universitet,Genetic and Molecular Epidemiology,Lund University Research Groups4 aut0 (Swepub:lu)med-plf |
| 700 | 1 | a Schwenk, Jochen M.u KTH,Science for Life Laboratory, SciLifeLab,Affinitets-proteomik4 aut0 (Swepub:kth)u1h7wtme |
| 700 | 1 | a Adamski, Jerzyu Institute of Experimental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore; Institute of Biochemistry, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia4 aut |
| 700 | 1 | a McCarthy, Mark I.u Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK; Genentech, South San Francisco, CA, USA4 aut |
| 700 | 1 | a Pearson, Ewanu Division of Population Health & Genomics, School of Medicine, University of Dundee, Dundee, UK4 aut |
| 700 | 1 | a Banasik, Karinau Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Department of Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark4 aut |
| 700 | 1 | a Rasmussen, Simonu Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark4 aut |
| 700 | 1 | a Brunak, Sørenu Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Department of Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark4 aut |
| 700 | 1 | a Froguel, Philippeu Inserm, Univ Lille, CHU Lille, Lille Pasteur Institute, EGID, Lille, France; Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK4 aut |
| 700 | 1 | a Thomas, Cecilia Engelu KTH,Affinitets-proteomik,Science for Life Laboratory, SciLifeLab,Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Department of Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark4 aut0 (Swepub:kth)u1ja1scu |
| 700 | 1 | a Häussler, Ragna S.u KTH,Affinitets-proteomik,Science for Life Laboratory, SciLifeLab4 aut0 (Swepub:kth)u1izv3pd |
| 700 | 1 | a Beulens, Jolineu Department of Epidemiology and Data Science, Amsterdam Public Health Research Institute, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands4 aut |
| 700 | 1 | a Rutters, Femkeu Department of Epidemiology and Data Science, Amsterdam Public Health Research Institute, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands4 aut |
| 700 | 1 | a Nijpels, Gielu Department of Epidemiology and Data Science, Amsterdam Public Health Research Institute, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands4 aut |
| 700 | 1 | a van Oort, Sabineu Department of Epidemiology and Data Science, Amsterdam Public Health Research Institute, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands4 aut |
| 700 | 1 | a Groeneveld, Lenkau Department of Epidemiology and Data Science, Amsterdam Public Health Research Institute, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands4 aut |
| 700 | 1 | a Elders, Petrau Department of General Practice, Amsterdam Public Health Research Institute, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands4 aut |
| 700 | 1 | a Giorgino, Toniu Biophysics Institute (IBF-CNR), National Research Council of Italy, Milan, Italy; Department of Biosciences, University of Milan, Milan, Italy4 aut |
| 700 | 1 | a Rodriquez, Marianneu Biotech & Biomarkers Research Department, Institut de Recherches Internationales Servier, Croissy sur Seine, France4 aut |
| 700 | 1 | a Nice, Rachelu Blood Sciences, Royal Devon and Exeter NHS Foundation Trust, Exeter, UK4 aut |
| 700 | 1 | a Perry, Mandyu Blood Sciences, Royal Devon and Exeter NHS Foundation Trust, Exeter, UK4 aut |
| 700 | 1 | a Bianzano, Susannau Boehringer Ingelheim International, Therapeutic Area CardioMetabolism and Respiratory Medicine, Ingelheim am Rhein, Germany4 aut |
| 700 | 1 | a Graefe-Mody, Ulrikeu Boehringer Ingelheim International, Therapeutic Area CNS, Retinopathies and Emerging Areas, Ingelheim am Rhein, Germany4 aut |
| 700 | 1 | a Hennige, Anitau Boehringer Ingelheim International, Medicine Cardiometabolism and Respiratory, Biberach an der Riss, Germany4 aut |
| 700 | 1 | a Grempler, Rolfu Boehringer Ingelheim International, Translational Medicine & Clinical Pharmacology, Biberach an der Riss, Germany4 aut |
| 700 | 1 | a Baum, Patricku Boehringer Ingelheim International, Translational Medicine & Clinical Pharmacology, Biberach an der Riss, Germany4 aut |
| 700 | 1 | a Stærfeldt, Hans Henriku Department of Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark4 aut |
| 700 | 1 | a Shah, Nishau Centre for Health, Law and Emerging Technologies (HeLEX), Faculty of Law, University of Oxford, Oxford, UK4 aut |
| 700 | 1 | a Teare, Harrietu Centre for Health, Law and Emerging Technologies (HeLEX), Faculty of Law, University of Oxford, Oxford, UK4 aut |
| 700 | 1 | a Ehrhardt, Beateu Centre for Mathematics and Algorithms for Data, University of Bath, Bath, UK4 aut |
| 700 | 1 | a Tillner, Joachimu Clinical Operations, Sanofi-Aventis Deutschland, Frankfurt, Germany4 aut |
| 700 | 1 | a Dings, Christianeu Clinical Pharmacy, Saarland University, Saarbrücken, Germany4 aut |
| 700 | 1 | a Lehr, Thorstenu Clinical Pharmacy, Saarland University, Saarbrücken, Germany4 aut |
| 700 | 1 | a Scherer, Ninau Clinical Pharmacy, Saarland University, Saarbrücken, Germany4 aut |
| 700 | 1 | a Sihinevich, Irynau Clinical Pharmacy, Saarland University, Saarbrücken, Germany4 aut |
| 700 | 1 | a Cabrelli, Louiseu Clinical Research Centre, Ninewells Hospital and Medical School, University of Dundee, Dundee, Scotland, UK, Scotland4 aut |
| 700 | 1 | a Loftus, Heatheru Clinical Research Centre, Ninewells Hospital and Medical School, University of Dundee, Dundee, Scotland, UK, Scotland4 aut |
| 700 | 1 | a Bizzotto, Robertou C.N.R. Institute of Neuroscience, Padova, Italy4 aut |
| 700 | 1 | a Tura, Andreau C.N.R. Institute of Neuroscience, Padova, Italy4 aut |
| 700 | 1 | a Dekkers, Koenu Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, the Netherlands4 aut |
| 700 | 1 | a Groop, L.u Lund University,Lunds universitet,Genomik, diabetes och endokrinologi,Forskargrupper vid Lunds universitet,Genomics, Diabetes and Endocrinology,Lund University Research Groups4 aut0 (Swepub:lu)endo-lgr |
| 700 | 1 | a Pasdar, N.A.4 aut |
| 700 | 1 | a Fitipaldi, H.u Lund University,Lunds universitet,Genetisk och molekylär epidemiologi,Forskargrupper vid Lunds universitet,Genetic and Molecular Epidemiology,Lund University Research Groups4 aut0 (Swepub:lu)hu3745fi |
| 700 | 1 | a Kurbasic, A.u Lund University,Lunds universitet,Genetisk och molekylär epidemiologi,Forskargrupper vid Lunds universitet,Genetic and Molecular Epidemiology,Lund University Research Groups4 aut0 (Swepub:lu)mats-aku |
| 700 | 1 | a Mutie, P.u Lund University,Lunds universitet,Genetisk och molekylär epidemiologi,Forskargrupper vid Lunds universitet,Genetic and Molecular Epidemiology,Lund University Research Groups4 aut0 (Swepub:lu)pa4264mu |
| 700 | 1 | a Pomares-Millan, H.u Lund University,Lunds universitet,Genetisk och molekylär epidemiologi,Forskargrupper vid Lunds universitet,Genetic and Molecular Epidemiology,Lund University Research Groups4 aut0 (Swepub:lu)hu7454po |
| 700 | 1 | a Abdalla, M.u University of Oxford4 aut |
| 710 | 2 | a Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Department of Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark; Copenhagen Research Centre for Mental Health, Mental Health Centre Copenhagen, Copenhagen University Hospital, Copenhagen, Denmarkb Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Department of Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark4 org |
| 773 | 0 | t Nature Biotechnologyd : Springer Natureg 41:3, s. 399-408q 41:3<399-408x 1087-0156x 1546-1696 |
| 856 | 4 | u https://doi.org/10.1038/s41587-022-01520-xy Fulltext |
| 856 | 4 | u http://dx.doi.org/10.1038/s41587-022-01520-xx freey FULLTEXT |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-330088 |
| 856 | 4 8 | u https://doi.org/10.1038/s41587-022-01520-x |
| 856 | 4 8 | u https://lup.lub.lu.se/record/13c6b992-22aa-4bcc-b353-dbd6f2f72642 |
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