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Contrast-enhanced d...
Contrast-enhanced dual-energy subtraction imaging using electronic spectrum-splitting and multi-prism x-ray lenses
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- Fredenberg, Erik, PhD, 1979- (författare)
- KTH,Medicinsk bildfysik
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- Cederström, Björn (författare)
- KTH,Medicinsk bildfysik
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Lundqvist, Mats (författare)
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- Ribbing, Carolina (författare)
- Uppsala universitet,Fasta tillståndets elektronik
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Åslund, Magnus (författare)
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- Diekmann, Felix (författare)
- Charité - Univ. Hospital (Germany)
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- Nishikawa, Robert (författare)
- Univ. of Chicago (United States)
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- Danielsson, Mats (författare)
- KTH,Medicinsk bildfysik
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(creator_code:org_t)
- San Diego, CA, USA : SPIE, 2008
- 2008
- Engelska.
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Serie: Proceedings of the Society of Photo-Optical Instrumentation Engineers, 0277-786X ; 6913
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Ingår i: Medical Imaging 2008 - Physics of Medical Imaging. - San Diego, CA, USA : SPIE. - 9780819470973 ; , s. 91310-91310
- Relaterad länk:
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https://kth.diva-por... (primary) (Raw object)
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http://arxiv.org/pdf...
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http://link.aip.org/...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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Abstract
Ämnesord
Stäng
- Dual-energy subtraction imaging (DES) is a method to improve the detectability of contrast agents over a lumpy background. Two images, acquired at x-ray energies above and below an absorption edge of the agent material, are logarithmically subtracted, resulting in suppression of the signal from the tissue background and a relative enhancement of the signal from the agent. Although promising, DES is still not widely used in clinical practice. One reason may be the need for two distinctly separated x-ray spectra that are still close to the absorption edge, realized through dual exposures which may introduce motion unsharpness. In this study, electronic spectrum-splitting with a silicon-strip detector is theoretically and experimentally investigated for a mammography model with iodinated contrast agent. Comparisons are made to absorption imaging and a near-ideal detector using a signal-to-noise ratio that includes both statistical and structural noise. Similar to previous studies, heavy absorption filtration was needed to narrow the spectra at the expense of a large reduction in x-ray flux. Therefore, potential improvements using a chromatic multi-prism x-ray lens (MPL) for filtering were evaluated theoretically. The MPL offers a narrow tunable spectrum, and we show that the image quality can be improved compared to conventional filtering methods.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinsk bioteknologi -- Biomedicinsk laboratorievetenskap/teknologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Medical Biotechnology -- Biomedical Laboratory Science/Technology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Radiologi och bildbehandling (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Radiology, Nuclear Medicine and Medical Imaging (hsv//eng)
Nyckelord
- mammography
- contrast-enhanced
- dual-energy subtraction
- x-ray optics
- multi-prism lens
- energy filtering
- Medical technology
- Medicinsk teknik
- TECHNOLOGY
Publikations- och innehållstyp
- ref (ämneskategori)
- kon (ämneskategori)
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