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Microalbuminuria an...
Microalbuminuria and Left Ventricular Functions in Type 2 Diabetes : A Quantitative Assessment by Stress Echocardiography in the Myocardial Doppler in Diabetes (MYDID) Study III
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- Govind, Satish C. (författare)
- BMJ Heart Center, Bangalore, India
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- Brodin, Lars-Åke (författare)
- Karolinska Institutet,KTH,Medicinsk teknik
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- Nowak, J. (författare)
- Karolinska Institutet
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- Arvind, S. R. (författare)
- Karolinska Institutet
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- Ramesh, S. S. (författare)
- BMJ Heart Center, Bangalore, India
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- Netyö, A. (författare)
- Karolinska Institute, Department of Clinical Physiology, Karolinska University Hospital at Huddinge, Stockholm, Sweden
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- Prasad, K.Y.M. (författare)
- BMJ Heart Center, Bangalore, India
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- Saha, S. (författare)
- Karolinska Institute, Department of Clinical Physiology, Karolinska University Hospital at Huddinge, Stockholm, Sweden
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(creator_code:org_t)
- 2009-07-12
- 2007
- Engelska.
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Ingår i: International Journal of Cardiology. - : Informa UK Limited. - 0167-5273 .- 1874-1754. ; 41:6, s. 363-369
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- Background. Left ventricular (LV) function might be altered in type 2 diabetes (DM) and microalbuminuria (MA) may accentuate the abnormalities. We sought to investigate whether additional LV dysfunction could be unmasked using tissue Doppler (TVE)-enhanced dobutamine stress echocardiography (TVE-DSE) in patients with DM+MA. Methods. Twenty seven DM subjects with MA, (DM+MA), 31 DM subjects without MA (DM-MA), and 13 Controls were evaluated using TVE-DSE. LV basal peak systolic (PSV), early (E') and late (A') diastolic velocities (cm/sec) at rest and peak stress were post-processed. LV filling pressure was assessed using E/E'ratio. Results. PSV and E'velocity at peak stress in the respective three groups were 13.7±1.0, 10.1±1.1, 10.0±1.2 for PSV; and 10.0±1.6, 5.0±1.4, 4.8±1.4 for E' (p < 0.001 for controls vs. both groups). E/E' at rest was 7.9±0.7 in the controls, 10.8±2.4 in DM-MA, and 11.0±2.2 in DM+MA (p < 0.01 Controls vs. both the DM groups). Conclusions. Patients with DM+MA do not have additional LV regional systolic and diastolic dysfunctions compared with DM-MA, as revealed by TVE-DSE, when controlled for glycemia levels, lipids, and treatment strategies.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Endokrinologi och diabetes (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Endocrinology and Diabetes (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Nyckelord
- Left ventricular function; Microalbuminuria; Tissue velocity echocardiography; Type 2 diabetes
- Diabetology
- Diabetologi
- Cardiology
- Kardiologi
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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