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Two-fraction and th...
Two-fraction and three-fraction continuous simulated moving bed separation of nucleosides
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Abel, S (författare)
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- Bäbler, Matthäus (författare)
- ETH, Inst Chem & Bioengn, Dept Chem & Appl Biosci
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Arpagaus, C (författare)
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Mazzotti, M (författare)
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Stadler, J (författare)
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(creator_code:org_t)
- Elsevier BV, 2004
- 2004
- Engelska.
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Ingår i: Journal of Chromatography A. - : Elsevier BV. - 0021-9673 .- 1873-3778. ; 1043:2, s. 201-210
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- A new experimental set-up and a new simulated moving bed (SMB) operation are presented in this work. A desktop SMB unit developed as a modification of the commercial AKTA(TM) explorer working platform has been utilized for the separation of different mixtures of nucleosides. Both two fraction and three fraction SMB separations have been carried out, the latter made possible by the adoption of a new SMB configuration and operating mode (three fraction SMB, 3F-SMB, operation). Experiments demonstrate the feasibility of the 3F-SMB operation, and confirm the trends predicted based on considerations about retention of the components to be separated along the unit.
Ämnesord
- TEKNIK OCH TEKNOLOGIER -- Kemiteknik -- Kemiska processer (hsv//swe)
- ENGINEERING AND TECHNOLOGY -- Chemical Engineering -- Chemical Process Engineering (hsv//eng)
- TEKNIK OCH TEKNOLOGIER -- Kemiteknik -- Farmaceutisk synteskemi (hsv//swe)
- ENGINEERING AND TECHNOLOGY -- Chemical Engineering -- Pharmaceutical Chemistry (hsv//eng)
Nyckelord
- simulated moving bed
- preparative chromatography
- nucleosides
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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