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On/off-switchable e...
On/off-switchable electrochemical sensor for folicacid based on molecularly imprinted technology.
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- Karimian, N (författare)
- Linköpings universitet,Biosensorer och bioelektronik,Tekniska högskolan
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- Zavar, M H A (författare)
- Department of Chemistry, Faculty of Sciences, Ferdowsi University of Mashhad, Mashhad, Iran
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- Chamsaz, M (författare)
- Department of Chemistry, Faculty of Sciences, Ferdowsi University of Mashhad, Mashhad, Iran
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- Turner, Anthony, 1950- (författare)
- Linköpings universitet,Biosensorer och bioelektronik,Tekniska högskolan,Biosensors & Bioelectronics
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- Tiwari, Ashutosh (författare)
- Linköpings universitet,Biosensorer och bioelektronik,Tekniska högskolan
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(creator_code:org_t)
- Elsevier BV, 2013
- 2013
- Engelska.
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Ingår i: Electrochemistry communications. - : Elsevier BV. - 1388-2481 .- 1873-1902. ; 36, s. 92-95
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- The combination of smart polymers with molecular imprinting offers a powerful tool to design more effective sensors and medical devices. In this study, a temperature sensitive amine-terminated poly(N-isopropylacrylamide) block with (N,N'-methylenebisacrylamide) cross-linker along with o-phenylenediamine was electropolymerised on a gold electrode in the presence of folic acid (FA) as template to produce an on/off-switchable molecularly imprinted polymer (MIP) affinity sensor for folic acid. Differential pulse voltammetry and cyclic voltammetry were used to characterise the FA-imprinted layer. Incubation of the MIP-modified electrode with FA resulted in a suppression of the ferro/ferricyanide redox process. The highest sensitivity of this temperature gated on/off-switchable folic acid sensor was achieved at 22 °C. Such switchable affinity materials offer considerable potential for the design of highly selective and controllable biosensors and immunoassays.
Ämnesord
- NATURVETENSKAP -- Kemi (hsv//swe)
- NATURAL SCIENCES -- Chemical Sciences (hsv//eng)
Nyckelord
- MIP
- Folic acid
- biosensor
- smart material
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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