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Virus Antibody Surv...
Virus Antibody Survey in Different European Populations Indicates Risk Association Between Coxsackievirus B1 and Type 1 Diabetes
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- Oikarinen, Sami (författare)
- University of Tampere, Finland
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- Tauriainen, Sisko (författare)
- University of Tampere, Finland University of Turku, Finland
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- Hober, Didier (författare)
- University of Lille 2, France CHR, France
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- Lucas, Bernadette (författare)
- University of Lille 2, France CHR, France
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- Vazeou, Andriani (författare)
- National Technical University of Athens, Greece
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- Sioofy-Khojine, Amirbabak (författare)
- University of Tampere, Finland
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- Bozas, Evangelos (författare)
- National Technical University of Athens, Greece
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- Muir, Peter (författare)
- Kings Coll London, England
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- Honkanen, Hanna (författare)
- University of Tampere, Finland
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- Ilonen, Jorma (författare)
- University of Turku, Finland University of Eastern Finland, Finland
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- Knip, Mikael (författare)
- Folkhalsan Research Centre, Finland University of Helsinki, Finland Helsinki University of Central Hospital, Finland Tampere University Hospital, Finland University of Tampere, Finland University of Helsinki, Finland
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- Keskinen, Paivi (författare)
- Tampere University Hospital, Finland University of Tampere, Finland
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- Saha, Marja-Terttu (författare)
- Tampere University Hospital, Finland University of Tampere, Finland
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- Huhtala, Heini (författare)
- University of Tampere, Finland
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- Stanway, Glyn (författare)
- University of Essex, England
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- Bartsocas, Christos (författare)
- National Technical University of Athens, Greece
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- Ludvigsson, Johnny (författare)
- Östergötlands Läns Landsting,Linköpings universitet,Avdelningen för kliniska vetenskaper,Hälsouniversitetet,Barn- och ungdomskliniken i Linköping
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- Taylor, Keith (författare)
- Queen Mary University of London, England
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- Hyoty, Heikki (författare)
- University of Tampere, Finland Pirkanmaa Hospital Dist, Finland
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(creator_code:org_t)
- 2014-01-16
- 2014
- Engelska.
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Ingår i: Diabetes. - : American Diabetes Association. - 0012-1797 .- 1939-327X. ; 63:2, s. 655-662
- Relaterad länk:
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https://diabetes.dia...
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https://urn.kb.se/re...
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https://doi.org/10.2...
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Abstract
Ämnesord
Stäng
- Enteroviruses (EVs) have been connected to type 1 diabetes in various studies. The current study evaluates the association between specific EV subtypes and type 1 diabetes by measuring type-specific antibodies against the group B coxsackieviruses (CVBs), which have been linked to diabetes in previous surveys. Altogether, 249 children with newly diagnosed type 1 diabetes and 249 control children matched according to sampling time, sex, age, and country were recruited in Finland, Sweden, England, France, and Greece between 2001 and 2005 (mean age 9 years; 55% male). Antibodies against CVB1 were more frequent among diabetic children than among control children (odds ratio 1.7 [95% CI 1.0-2.9]), whereas other CVB types did not differ between the groups. CVB1-associated risk was not related to HLA genotype, age, or sex. Finnish children had a lower frequency of CVB antibodies than children in other countries. The results support previous studies that suggested an association between CVBs and type 1 diabetes, highlighting the possible role of CVB1 as a diabetogenic virus type.
Nyckelord
- MEDICINE
- MEDICIN
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Diabetes
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Oikarinen, Sami
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Tauriainen, Sisk ...
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Hober, Didier
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Lucas, Bernadett ...
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Vazeou, Andriani
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Sioofy-Khojine, ...
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Bozas, Evangelos
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Muir, Peter
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Honkanen, Hanna
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Ilonen, Jorma
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Knip, Mikael
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Keskinen, Paivi
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Saha, Marja-Tert ...
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Huhtala, Heini
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Stanway, Glyn
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Bartsocas, Chris ...
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Ludvigsson, John ...
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Taylor, Keith
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Hyoty, Heikki
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Linköpings universitet