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The impact of calci...
The impact of calcium volume and distribution in aortic root injury related to balloon-expandable transcatheter aortic valve replacement
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- Hansson, Nicolaj C. (författare)
- Aarhus University Hospital, Denmark
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- Norgaard, Bjarne L. (författare)
- Aarhus University Hospital, Denmark
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- Barbanti, Marco (författare)
- St Pauls Hospital, Canada; University of Catania, Italy
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- Nielsen, Niels Erik (författare)
- Linköpings universitet,Avdelningen för kardiovaskulär medicin,Hälsouniversitetet,Region Östergötland, Kardiologiska kliniken US
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- Yang, Tae-Hyun (författare)
- St Pauls Hospital, Canada; Inje University, South Korea
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- Tamburino, Corrado (författare)
- University of Catania, Italy
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- Dvir, Danny (författare)
- St Pauls Hospital, Canada
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- Jilaihawi, Hasan (författare)
- Cedars Sinai Heart Institute, CA USA
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- Blanke, Philip (författare)
- University Hospital Freiburg, Germany
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- Makkar, Raj R. (författare)
- Cedars Sinai Heart Institute, CA USA
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- Latib, Azeem (författare)
- EMO GVM Centre Cuore Columbus, Italy; Ist Science San Raffaele, Italy
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- Colombo, Antonio (författare)
- EMO GVM Centre Cuore Columbus, Italy; Ist Science San Raffaele, Italy
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- Tarantini, Giuseppe (författare)
- University of Padua, Italy
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- Raju, Rekha (författare)
- St Pauls Hospital, Canada
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- Wood, David (författare)
- St Pauls Hospital, Canada
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- Andersen, Henning R. (författare)
- Aarhus University Hospital, Denmark
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- Ribeiro, Henrique B. (författare)
- University of Laval, Canada
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- Kapadia, Samir (författare)
- Cleveland Clin, OH 44106 USA
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- Min, James (författare)
- Cedars Sinai Heart Institute, CA USA
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- Feuchtner, Gudrun (författare)
- Medical University of Innsbruck, Austria
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- Gurvitch, Ronen (författare)
- Royal Melbourne Hospital, Australia
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- Alqoofi, Faisal (författare)
- University of Calgary, Canada
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- Pelletier, Marc (författare)
- New Brunswick Heart Centre, Canada
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- Paolo Ussia, Gian (författare)
- University of Roma Tor Vergata, Italy
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- Napodano, Massimo (författare)
- EMO GVM Centre Cuore Columbus, Italy; Ist Science San Raffaele, Italy
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- de Brito, Fabio Sandoli Jr. (författare)
- Hospital Israelita Albert Einstein, Brazil
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- Kodali, Susheel (författare)
- Columbia University, NY USA
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- Pache, Gregor (författare)
- University Hospital Freiburg, Germany
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- Canovas, Sergio J. (författare)
- Arrixaca University Hospital, Spain
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- Berger, Adam (författare)
- St Pauls Hospital, Canada
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- Murphy, Darra (författare)
- St Pauls Hospital, Canada
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- Svensson, Lars G. (författare)
- Cleveland Clin, OH 44106 USA
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- Rodes-Cabau, Josep (författare)
- University of Laval, Canada
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- Leon, Martin B. (författare)
- Columbia University, NY USA
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- Webb, John G. (författare)
- St Pauls Hospital, Canada
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- Leipsic, Jonathon (författare)
- St Pauls Hospital, Canada
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(creator_code:org_t)
- ELSEVIER SCIENCE INC, 2015
- 2015
- Engelska.
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Ingår i: JOURNAL OF CARDIOVASCULAR COMPUTED TOMOGRAPHY. - : ELSEVIER SCIENCE INC. - 1934-5925. ; 9:5, s. 382-392
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Background: A detailed assessment of calcium within the aortic root may provide important additional information regarding the risk of aortic root injury during transcatheter heart valve replacement (TAVR). Objective: We sought to delineate the effect of calcium volume and distribution on aortic root injury during TAVR. Methods: Thirty-three patients experiencing aortic root injury during TAVR with a balloon-expandable valve were compared with a control group of 153 consecutive TAVR patients without aortic root injury (as assessed by post-TAVR multidetector CT). Using commercial software to analyze contrast-enhanced pre-TAVR CT scans, caltium volume was determined in 3 regions: (1) the overall left ventricular outflow tract (LVOT), extending 10 mm down from the aortic annulus plane; (2) the upper LVOT, extending 2 mm down from the annulus plane; and (3) the aortic valve region. Results: Calcium volumes in the upper LVOT (median, 29 vs 0 mm(3); P less than .0001) and overall LVOT (median, 74 vs 3 mm(3); P = .0001) were higher in patients who experienced aortic root injury compared with the control group. Calcium in the aortic valve region did not differ between groups. Upper LVOT calcium volume was more predictive of aortic root injury than overall LVOT calcium volume (area under receiver operating curve [AUG]; 0.78; 95% confidence interval, 0.69-0.86 vs AUC, 0.71; 95% confidence interval, 0.62-0.82; P = .010). Upper LVOT calcium below the noncoronary cusp was significantly more predictive of aortic root injury compared to calcium underneath the right coronary cusp or the left coronary cusp (AUC, 0.81 vs 0.68 vs 0.64). Prosthesis oversizing greater than20% (likelihood ratio test, P = .028) and redilatation (likelihood ratio test, P = .015) improved prediction of aortic root injury by upper LVOT calcium volume. Conclusion: Calcification of the LVOT, especially in the upper LVOT, located below the noncoronary cusp and extending from the annular region, is predictive of aortic root injury during TAVR with a balloon-expandable valve. (C) 2015 Society of Cardiovascular Computed Tomography. All rights reserved.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine (hsv//eng)
Nyckelord
- Aortic root calcification; Aortic root injury; Multidetector computed tomography; Transcatheter aortic valve replacement
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- Av författaren/redakt...
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Hansson, Nicolaj ...
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Norgaard, Bjarne ...
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Barbanti, Marco
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Nielsen, Niels E ...
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Yang, Tae-Hyun
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Tamburino, Corra ...
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visa fler...
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Dvir, Danny
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Jilaihawi, Hasan
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Blanke, Philip
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Makkar, Raj R.
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Latib, Azeem
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Colombo, Antonio
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Tarantini, Giuse ...
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Raju, Rekha
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Wood, David
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Andersen, Hennin ...
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Ribeiro, Henriqu ...
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Kapadia, Samir
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Min, James
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Feuchtner, Gudru ...
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Gurvitch, Ronen
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Alqoofi, Faisal
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Pelletier, Marc
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Paolo Ussia, Gia ...
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Napodano, Massim ...
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de Brito, Fabio ...
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Kodali, Susheel
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Pache, Gregor
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Canovas, Sergio ...
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Berger, Adam
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Murphy, Darra
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Svensson, Lars G ...
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Rodes-Cabau, Jos ...
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Leon, Martin B.
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Webb, John G.
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Leipsic, Jonatho ...
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